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Research on influencing factors of cognitive function in the middle-aged and elderly people: an empirical analysis based on CHARLS

Published on Journal of Mathematical Medicine 2026,39(5):319-327.
2930 times 691 times

ZHU Xinya FENG Jiayun YE Sha SHEN Jie MAI Yiyi RONG Fen

Middle-aged and elderly people Cognitive function Influencing factors Logistic regression model Random forest model
Details
Environmental chemical exposure and antidepressant efficacy: mechanisms and advances in precision pharmacology prediction models

Published on Chinese Journal of Pharmacoepidemiology 2026,35(5): 579-588.
2120 times 462 times

WANG Pei CHEN Wanying SHANG Nan ZHANG Ruifen

Antidepressants Environmental exposure Blood-brain barrier Drug efficacy Envir-onmental chemical pollutants Precision pharmacology
Details
Research progress in pharmacological treatment of mitral regurgitation

Published on Chinese Journal of Pharmacoepidemiology 2026,35(5):571-578.
2363 times 509 times

LU Qianhong LYU Junxing WU Yongjian XU Haiyan

Mitral regurgitation Pharmacological treatment Valvular heart disease Guideline-directed medical therapy Prognosis
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Visualization analysis of off-label drug use of Chinese patent medicine based on CiteSpace software

Published on Chinese Journal of Pharmacoepidemiology 2026,35(5):563-570.
2094 times 585 times

SONG Yifei WANG Hui YANG Wenbao CHEN Xin JIA Shengwei ZHANG Huiyue

Chinese patent medicine Off-label use Bibliometrics Visual analysis Rational drug use
Details
Cost-effectiveness analysis of sacituzumab tirumotecan versus platinum-based chemotherapy as second-line treatment for progressed EGFR-mutant non-small-cell lung cancer

Published on Chinese Journal of Pharmacoepidemiology 2026,35(5):553-562.
2818 times 580 times

JIN Lijun ZHANG Lele HAN Lu LYU Zhenye

Sacituzumab tirumotecan Non-small cell lung cancer EGFR mutation Quality adiusted life year Incremental Cost-effectiveness ratio Cost-effectiveness analysis Scenaio analysis
Details
Signal mining and analysis of adverse events associated with the use of beta-1 blockers in children based on the FAERS database

Published on Chinese Journal of Pharmacoepidemiology 2026,35(5):542-552.
2067 times 559 times

CHANG Qiuyue SHANG Shenglan ZHAO Yan YU Mengchen YU Airong

Metoprolol Bisoprolol Atenolol Esmolol Adverse drug events Signal mining Pharmacovigilance
Details
Experimental study on the protective effect and safety of different doses of quercetin on the intestinal barrier in sepsis

Published on Chinese Journal of Pharmacoepidemiology 2026,35(5):517-525.
2140 times 576 times

FENG Mingzhi SUN Yan ZHANG Jun

Quercetin Sepsis Intestinal epithelial barrier Anti-inflammatory Infection
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Expert consensus for off-label drug use of rare diseases (2026 edition)

Published on Chinese Journal of Pharmacoepidemiology 2026,35(5):493-507.
3290 times 952 times

DUAN Yuehan CHEN Chaoyang ZHANG Yu CUI Yi-min WANG Shengfeng DING Jie Working Group of the Expert Consensus for Off-Label Drug Use of Rare Diseases

Rare disease Off-label drug use Expert consensus Thomson evidence grading system
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Guide on Methodological Standards in Pharmacoepidemiology (2nd edition) and their series interpretation (17): application of predictive models in drug effectiveness and safety evaluation

Published on Chinese Journal of Pharmacoepidemiology 2026,35(5):481-492.
2724 times 657 times

NIE Xiaolu WU Yunxiao ZHAO Houyu ZHAN Siyan SUN Feng

Predictive models Pharmacoepidemiology Precision Medicine Ef-fectiveness evaluation Safety evaluation Heterogeneity of treatment effects Biomarkers
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Klinefelter syndrome with diabetes ketoacidosis as the first manifestation: a case report and literature analysis

Published on Journal of Mathematical Medicine 2026,39(4):314-318.
3442 times 948 times

LIU Xiaoyu YANG Fan WU Jing YIN Wanling

Klinefelter syndrome Hypogonadism Gynecomastia Diabetic ketoacidosis Osteoporosis
Details
Fertility-sparing treatment for ovarian yolk sac tumor in a woman of childbearing age: a case report

Published on Journal of Mathematical Medicine 2026,39(4):307-313.
5066 times 851 times

HE Li CHEN Yuyan WEI Yi ZHANG Fan

Ovarian yolk sac tumor Ovarian malignant germ cell tumor Childbearing age Fertility-sparing treatment
Details
Hemostatic management during the perioperative period in a patient with severe hemophilia A and high-titer FⅧ inhibitors: a case report

Published on Journal of Mathematical Medicine 2026,39(4):301-306.
3255 times 879 times

WANG Ziqing ZHANG Xian

Hemophilia A Factor Ⅷ inhibitor Recombinant activated factor Ⅶ Os-teofascial Compartment syndrome
Details
Research progress of traditional Chinese medicine on the regulation of Notch signaling pathway in the treatment of rheumatoid arthritis

Published on Journal of Mathematical Medicine 2026,39(4):294-300.
4048 times 837 times

LI Mingxia CHEN Junlong HE Bianqiang HE Wenkui GAO Wanpeng

Rheumatoid arthritis Notch signaling pathway Traditional Chinese medicine Mechanism
Details
Influencing factors of healthcare-seeking delay for pulmonary tuberculosis pa-tients in China from 2014 to 2024: a Meta-analysis

Published on Journal of Mathematical Medicine 2026,39(4):282-293.
3599 times 746 times

HUANG Chen AN Xuemei YANG Tingyu HONG Zhongxi LUO Yongyuan XIONG Xiya ZHOU Xianyu

Tuberculosis Healthcare-seeking delay Influencing factors Meta-analysis
Details
Efficacy analysis of extended curettage combined with denosumab adjuvant therapy for giant cell tumor of the bone

Published on Journal of Mathematical Medicine 2026,39(4):273-281.
3533 times 801 times

WEN Riyou LE Guoping

Giant cell tumor of the bone Extended curettage Denosumab Relapse rate
Details
A study on the mechanisms regulation of BIRC5 expression in prostate cancer and its potential targeted therapy

Published on Journal of Mathematical Medicine 2026,39(4):263-272.
3010 times 771 times

YE Junjie CHEN Yunyi HUANG Yingxin LI Yanliang WANG Huifeng

Carcinoma of prostate BIRC5 gene Targeted therapy Mechanism
Details
SERPINE1 affects the metastasis of colon cancer by regulating MMP-9 and MMP-2

Published on Journal of Mathematical Medicine 2026,39(4):252-262.
2903 times 711 times

CHEN Dehe DING Pengpeng LI Wending LI Hongtao

Colon cancer SERPINE1 MMP-9 MMP-2 Metastasis
Details
Bibliometric analysis of the research status, hotspots and trends in the field of prescription comment in China

Published on Journal of Mathematical Medicine 2026,39(4):241-251.
3471 times 876 times

YUAN Jiachen YU Lu CHEN Yuqin

Prescription comment Bibliometrics CiteSpace VOSviewer Hotspots Trends
Details
Discussion on the field practice teaching mode of medicinal botany based on the orientation of scientific research innovation practice

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):715-720.
2351 times 453 times

CHEN Peng PENG Yansong CHEN Fuchao HE Jingsheng ZOU Youquan TANG Jun LIU Gang ZHOU Benhong

Medicinal botany Field practice Innovative practice Digital intelligence technology Ethnic medicine Teaching assessment Talent cultivation
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Design and application scenarios of digital monitoring model for online drug sales——based on Shanghai online drug circulation supervision system

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):707-714.
2498 times 589 times

ZHUANG Wenyi ZHAO Yuxiang FENG Xiao SHEN Kan WANG Haibo GUO Aiwei ZHOU Fengwu WANG Guangping

Drug Online Circulation Digitalization Monitoring Robotic process automation Case Investigation and Handling Database
Details