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Recent advances of non-viral vectors in DNA drug delivery field

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):520-529.
2936 times 523 times

LIU Hanxiao YANG Xuehua LIU Zhengping MAO Kaifan XUE Song LI Dawei TANG Xuan

Non-viral vectors DNA drugs Delivery systems Targeted delivery Nanocarriers Biocompatibility Gene therapy Clinical translation
Details
Overview of the mechanism and application of traditional Chinese medicine for soothing the liver and relieving depression in the prevention and treatment of obesity

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):512-519.
3074 times 592 times

DOU Xia LI Yingmei LIU Wenrong XU Meng YANG Xinrong JIN Ziming

Obesity Traditional Chinese medicine for soothing the liver and relieving depressio Mechanism of action Lipid metabolism Insulin resistance Chronic inflammation
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Research progress on the function of FKBP5 and its role in neuropsychiatric disorders

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):502-511.
2643 times 580 times

XING Jiaxin ZHAO Mingyi SONG Rui LI Hong

FK506 binding protein 5 Neuropsychiatric disorders Protein structure Molecular function Expression regulation Therapeutic target Drug research Clinical application prospects
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Analysis of chemical components and pharmacological effects of Zingiberis rhizoma

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):491-501.
3939 times 648 times

DUAN Xiaonan DI Qing YU Ran SUN Cuige ZHENG Xiaonan SUN Guyue ZHAO Xiangxuan

Zingiberis rhizoma Chemical composition Pharmacological effect Diphenylheptanes Flavonoids Anti-tumor Antioxidant Lowering blood sugar
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Systematic review and Meta-analysis of traditional Chinese medicine in the treatment of mild cognitive impairment

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):477-490.
3880 times 520 times

ZENG Baoqi TANG Chunbian DOU Lin SHENG Feng SUN Feng

Traditional Chinese medicine Cognitive function Mild cognitive impairment Activities of daily living Meta-analysis Randomized controlled trial Adverse reaction Safety
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Patent technology analysis of angiotensin receptor-neprilysin inhibitor sacubitril valsartan

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):466-476.
3409 times 578 times

GAN Yu SHI Xiaorong

Sacubitril valsartan Entresto Co-crystals Patent technology analysis Patent layout
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Analysis of the safety profile of zavegepant based on the FAERS database and comparison with CGRP-targeted drugs

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):455-465.
2876 times 570 times

XIE Jinlian WANG Qing ZHANG Xingfei ZHANG Yaxin WU Qian MA Junlong KUANG Yun GUO Chengxian

Calcitonin gene-related peptide-targeted medication Zavegepant FAERS database Signal mining Disproportionality analysis Bayesian confidence propagation neural network Adverse events Pharmacovigilance
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Visualization of research hotspots and trends in traditional Chinese medicine treatment for liver cancer from 2006 to 2025

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):442-454.
3480 times 539 times

ZANG Guojie HUO Lina WU Meiyuan WANG Jian LIU Jinwei

Bibliometrics Traditional Chinese medicine Liver cancer Visual analytics CiteSpace VOSviewer Network pharmacology Molecular docking Cinobufagin Matrine Quercetin Flavonoids
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Visualization analysis of chemical components and pharmacological effects of Angelica sinensis based on VOSviewer and CiteSpace

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):430-441.
3529 times 543 times

MA Yantao ZHANG Shengjie ZHU Yajun LI Min ZHANG Juanhong LI Donghua

Angelica sinensis Chemical composition Pharmacological action VOSviewer CiteSpace Visualization analysis
Details
Quality evaluation of Serissa serissoides based on UPLC fingerprint and multi-index constituents

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):423-429.
2543 times 489 times

CHEN Qing ZHU Xuan SHAN Shengnan ZUO Chengbin WANG Mengjia ZHANG Xia

Serissa serissoides Fingerprint Content determination Ultra-performance liquid chromatography Quality evaluation Multivariate statistical analysis Common peaks Component differences
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Analysis of inorganic elements in Aconitum vilmorinianum Kom. by ICP-MS combined with chemometric methods

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):412-422.
2655 times 666 times

ZHANG Yanming LIU Yingying LIU Yi LIU Chengya HUANG Lijia PU Lianxin LI Zhiyuan

Aconitum vilmorinianum Kom. Inorganic elements Microwave digestion Inductively coupled plasma mass spectrometry Chemometrics Content determination Analysis Geographical origin
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Quality evaluation of Imperata cylindrica Rhizome and its carbonized product based on fingerprint chromatography and multi-component quantification combined with chemometrics

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):403-411.
2489 times 496 times

LI Jiaoyan LIU Xiaoxia ZHENG Ronghui DENG Congyou HUANG Lisha LUO Yijing SU Chunzhi ZHANG Yuai ZHOU Lin SUN Dongmei

Imperata cylindrica Rhizome Imperata cylindrica Carbonisata Ultra performance liquid chromatography Fingerprints Content determination Cluster analysis Principal component analysis Orthogonal partial least squares-discriminant analysis
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Optimization of preparation and evaluation of Angelica sinensis volatile oil inclusion complex based on orthogonal experiment combined with BP neural network

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):394-402.
2564 times 479 times

QIU Dawei HUANG Mengqiu LI Yanfang ZHANG Yulong LIU Zihao ZHANG Wei WANG Yannian

Angelica sinensis volatile oil Inclusion technology Orthogonal experiment Back-propagation neural network Fingerprint Entropy weight method β-cyclodextrin
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Predicting the differential efficacy of vitiligo between Tripterygium wilfordii and Tripterygium hypoglaucum and screening for candidate key microRNAs based on their main triterpene components

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):383-393.
2461 times 460 times

ZHAO Jiangyi ZENG Qin CAI Beilei LIU Qiancheng LI Yongjun ZHAO Jianquan WANG Jiangrui

Tripterygium wilfordii Tripterygium hypoglaucum Network pharmacology Molecular docking Triterpene components Vitiligo Pharmacological differences microRNA
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Optimization of the extraction process of damp-removing weight loss paste based on network pharmacology and Box-Behnken response surface methodology

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):371-382.
2803 times 655 times

LIU Shanshan WANG Wanru CHENG Manru XIAO Yutong CHENG Jiangxue GUO Dongyan ZHAI Bingtao

Damp-removing weight loss paste Network pharmacology Analytic hierarchy process Entropy weight method Box-Behnken response surface methodology Extraction process Single-factor experiments
Details
Integrating network pharmacology and molecular docking to elucidate the therapeutic mechanisms of Foeniculum vulgare against hepatocellular carcinoma

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):361-370.
3155 times 576 times

DENG Xiaying ZHAO Xiangxuan

Foeniculum vulgare Network pharmacology Network targets Hepatocellular carcinoma Mechanism of action Molecular docking Targeted therapy Natural products
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Analysis of the clinical efficacy and safety of single-port versus three-port totally extraperitoneal repair in the treatment of inguinal hernia

Published on New Medicine 2026,36(3):355-360.
2612 times 722 times

WANG Keyi WU Chong GUO Xingpei LIU Hansong GAO Lei

Inguinal hernia Single-port laparoscopic totally extraperitoneal repair Three-port laparoscopic totally extraperitoneal repair Clinical efficacy
Details
Research progress of nuclear receptor-binding SET domain protein 2 in colorectal cancer

Published on New Medicine 2026,36(3):348-354.
2202 times 695 times

REN Peng LIU Caixia

Nuclear receptor-binding SET domain protein 2 Colorectal cancer Epigenetics Histone methylation
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Role and related mechanisms of Porphyromonas gingivalis in the occurrence and development of digestive system tumors

Published on New Medicine 2026,36(3):342-347.
2289 times 669 times

LI Jingya SUN Jiachun KONG Jinyu GAO Shegan

Porphyromonas gingivalis Digestive system Tumor pathogenesis and progression Molecular mechanism
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Biomechanical perspective of prostate cancer: pathological mechanism, diagnostic innovation and targeted intervention

Published on New Medicine 2026,36(3):335-341.
2279 times 756 times

GAO Jin GUO Jing MI Zishuo CHEN Hao

Prostate cancer Biomechanics Tumor microenvironment Tissue stiffness Extracellular matrix remodeling Elastography Fluid shear stress
Details