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Wuhan University
Zhongnan Hospital of Wuhan University
Center for Evidence-Based and Translational Medicine of Wuhan University
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Literature
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Latest literature
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Study on the antianxiety effect of xanthohumol by inhibiting FKBP51 in the brain
Published on
Frontiers in Pharmaceutical Sciences
2026,30(1):42-51.
1326 times
271 times
SHAO Qi
ZHANG Jing
MA Shanbo
ZHANG Kun
CHONG Ye
Xanthohumol
FKBP51
Anxiety disorder
Brain-derived neurotrophic factor
Adeno-associated virus
Molecular docking
Open field test
Elevated plus-maze
Details
Exploration of the molecular mechanism of Guizhi Tang’s regulation on liver lipid metabolism based on multi-omics analysis
Published on
Frontiers in Pharmaceutical Sciences
2026,30(1):30-41.
1514 times
299 times
SONG Haijin
SONG Qi
DOU Baokai
ZHANG Huanhuan
HUO Hairu
SUI Feng
Guizhi Tang
Transcriptomics
Lipidomics
Lipid metabolism
Pungent-warm medicinal property
Molecular mechanism
Liver
Protein-protein interaction
Details
The mechanism of action of Cassiae Semen for constipation based on network pharmacology analysis
Published on
Frontiers in Pharmaceutical Sciences
2026,30(1):23-29.
1650 times
293 times
SUN Qiqi
MAO Weiru
WANG Yuheng
YUAN Meng
WU Xinyu
YAN Hailong
WANG Kun
Cassiae Semen
Constipation
Network pharmacology
Molecular docking
Molecular dynamics simulation
Prostaglandin-endoperoxide synthase 2
Tumor necrosis factor
Details
Comprehensive analysis of quality markers for Xiaoding ointment based on multi-dimensional feature fusion
Published on
Frontiers in Pharmaceutical Sciences
2026,30(1):12-22.
1662 times
323 times
CHANG Dengxi
LI Wenxia
DAI Haoen
ZHANG Yan
CHANG Chengdong
Xiaoding ointment
Multi-dimensional feature network
Quality marker
Component analysis
Molecular docking
Quality control
Pharmacological effects
Details
Exploring the in vitro anti-tumor effect and mechanism of Rumex chalepensis based on network pharmacology
Published on
Frontiers in Pharmaceutical Sciences
2026,30(1):2-11.
1541 times
342 times
GUO Changhong
YAN Guangjun
MIAO Qing
LIU Limei
XU Jing
LIU Chong
WANG Yejing
XIANG Caiqiong
Rumex chalepensis
Network pharmacology
Gastric cancer
PI3K/Akt signaling pathway
Apoptosis
Cell cycle arrest
Multi-target action
Natural anti-tumor drug
Details
Analysis of disease burden and future trends of chronic hepatitis C among individuals aged ≥50 years in China and globally from 1990 to 2021
Published on
Chinese Journal of Pharmacoepidemiology
2026,35(2):164-172.
1597 times
446 times
CHEN Si
CHEN Guannan
CHEN Qian
ZHAO Wei
Chronic hepatitis C
Disease burden
Incidence
Disability-adjusted life years
Details
Efficacy of Tangganjian pills and semaglutide on patients with type 2 diabetes and obesity and its impacts on intestinal mucosal barrier function and serum kisspeptin
Published on
Chinese Journal of Pharmacoepidemiology
2026,35(2):133-139.
1550 times
414 times
HU Lijuan
ZHU Hao
WAN Jing
Tangganjian pill
Semaglutide
Type 2 diabetes
Obesity
Intestinal mucosal barrier function
Kisspeptin
Details
A case report of rhabdomyolysis, liver and kidney dysfunction induced by capecitabine tablets
Published on
Chinese Journal of Pharmacoepidemiology
2026,35(2):237-240.
1561 times
387 times
YANG Saicheng
XIA Xiuyuan
Capecitabine
Rhabdomyolysis
Liver dysfunction
Kidney dysfunction
Adverse drug reactions
Details
Adverse drug event signal mining of ezetimibe monotherapy and compound preparations based on the FAERS database
Published on
Chinese Journal of Pharmacoepidemiology
2026,35(2):156-163.
1817 times
424 times
HUANG Yan
YU Yang
Ezetimibe
Single tablet compound preparation containing ezetimibe
Combination therapy
Adverse drug event
Signal mining
Pharmacovigilance
Details
Rhabdomyolysis induced by concomitant voriconazole and trimethoprim-sulfamethoxazole in a patient with pulmonary fungal infection: a case report
Published on
Chinese Journal of Pharmacoepidemiology
2026,35(2):221-226.
1447 times
370 times
ZHANG Jiajun
WANG Zhen
ZHOU Ying
ZHANG Peng
GONG Xuepeng
Voriconazole
Trimethoprim-sulfamethoxazole
Rhabdomyolysis
Adverse drug reaction
Details
A survey of the current status of tetanus passive immunization agent application in children's hospitals
Published on
Chinese Journal of Pharmacoepidemiology
2026,35(2):147-155.
1816 times
431 times
LIN Jinxiang
CHEN Yushuang
KE Huichao
WANG Jing
ZHANG Qingchi
Tetanus
Children
Tetanus antitoxin
Human tetanus immunoglobulin
Immunoprophylaxis
Potentially unnecessary use
Details
Application of transformative learning theory in hysteroscopy teaching and training to trainee physicians
Published on
Journal of Mathematical Medicine
2026,39(1):75-80.
1284 times
308 times
WANG Jing
SONG Dongmei
ZHOU Qiaoyun
XIA Enlan
HUO Jing
ZHANG Xin
JIN Shengyang
]HUANG Xiaowu
Transformative learning theory
Trainee physicians
Hysteroscopy
Teaching
Critical reflection
Details
Challenges and system construction of reproductive medicine ethics education
Published on
Journal of Mathematical Medicine
2026,39(1):68-74.
1335 times
317 times
FAN Qigang
KANG Jiawei
ZHANG Yuanzhen
WANG Mei
Reproductive medicine
Medical ethics
Ethical education
Artificial intelligence
Clinical practice
Details
Analysis of the evidence mapping of clinical studies on the treatment of osteoporosis with Chinese patent medicines
Published on
Journal of Mathematical Medicine
2026,39(1):58-67.
1987 times
372 times
CHEN Tianxin
ZHU Yuqi
ZHANG Shuai
YANG Shengping
Osteoporosis
Chinese patent medicines
Clinical studies
Systematic review
Meta-analysis
Evidence mapping
Details
Exploring the potential pathway of puerarin in the treatment of oral submucous fibrosis based on bioinformatics methods and cell experiments
Published on
Journal of Mathematical Medicine
2026,39(1):45-57.
1578 times
385 times
LU Ruqing
GUO Sheng
PENG Jiamei
LI Yijie
LIU Gen
Puerarin
Oral submucous fibrosis
Bioinformatics
Network pharmacology
Molecular docking
Molecular dynamics simulation
Cell experiments
Details
Visual analysis of research hotspots and trends in the association between senile sarcopenia and mitochondria based on Web of Science database
Published on
Journal of Mathematical Medicine
2026,39(1):34-44.
2742 times
324 times
YU Ruoru
FENG Cheng
ZHENG Shuyu
WU Lei
YONG Rulin
Senile sarcopenia
Mitochondria
Web of Science
Bibliometrics
Visual analysis
Details
Epidemiological characteristics, influencing factors, and prevention and control effects of hand, foot and mouth disease in Enshi prefecture from 2010 to 2020
Published on
Journal of Mathematical Medicine
2026,39(1):24-33.
1376 times
323 times
SU Yanwen
WU Yun
SUN Qiu
GUO Caihong
WANG Lianwen
Hand
foot and mouth disease
Bayesian spatiotemporal model
SARIMA model
Spatiotemporal characteristics
Influencing factors
Details
Analysis and prediction of the changing trend of the disease burden of tension-type headache in China from 1990 to 2021
Published on
Journal of Mathematical Medicine
2026,39(1):12-23.
1779 times
395 times
XU Xinyu
LIU Yuquan
REN Peihua
ZHANG Yuxuan
YUN Zixuan
YUAN Yanning
SHI Wenyan
LUO Qiaoshan
ZHANG Kun
XING Juanli
Tension-type headache
Disease burden
Incidence
Prevalence
Disability-adjusted life year
Joinpoint regression analysis
Bayesian age-period-cohort model
Details
Search strategies for systematic review and Meta-analysis: from PICO to large language models
Published on
Journal of Mathematical Medicine
2026,39(1):2-11.
1630 times
363 times
HUANG Sidie
CUI Nuan
ZHANG Wen
ZENG Yidi
LI Lin
LI Jinxia
LIANG Hao
Systematic review
Meta-analysis
Retrieval strategy
PICO
Large language models
Details
Message from the editors-in-chief
Published on
Chinese Journal of Pharmacoepidemiology
2026,35(1):1.
1304 times
333 times
ZHAN Siyan
XIN Huawen
ZHAI Suodi
Details
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