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Research progress on the relationship between vitamin D and pediatric sepsis

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):699-706.
2479 times 552 times

ZHU Liran XIA Wenwen WANG Zhen CUI Wei CAI Ming LIU Haipeng

Pediatric sepsis Vitamin D 25-hydroxyvitamin D3 Immune regulation Inflammatory response Clinical outcomey
Details
Research progress on the hepatoprotective effects and safety evaluation of sophocarpine

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):692-698.
2166 times 531 times

JIANG Jingjing WANG Changlin SONG Chunhong LI Yanan

Sophocarpine Hepatoprotective effect Safety evaluation Lipid metabolism An-ti-fibrosis Anti-inflammatory Anti-tumor Hepatotoxicity Acute toxicity
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Research progress on therapeutic strategies and mechanisms of action of traditional Chinese medicines with “medicine-food homology” in the prevention and treatment of chemo-therapy-induced myelosuppression

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):679-691.
3019 times 644 times

CHEN Weishi LI Jing LI Jing HAN Tao

Chemotherapy-induced myelosuppression Medicine-food homology Etiology and pathogenesis Treatment strategies Characteristics of traditional Chinese medicine Active ingredients Mechanism of action Medullary hematopoiesis
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Research progress on chemical components and pharmacological effects of Anisi Stellati Fructus

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):668-678.
3046 times 691 times

YU Ran DI Qing SUN Guyue ZHAO Xiangxuan

Anisi Stellati Fructus Chemical components Pharmacological effect Immune regulation Antioxidation Flavonoids Antibacterial Antitumor
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Investigation and analysis on the current status of high-alert medications management and pharmacists’ cognition in medical institutions in Hubei Province

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):657-667.
2349 times 554 times

RONG Xinyi LI Wei ZHANG Chengliang YU Zaoqin

High-alert medications Pharmacist Management status Cognitive level Influencing factors
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Adverse event signal mining and analysis of tucatinib based on the FAERS database

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):649-656.
2568 times 643 times

ZHAO Jun ZHAO Zhenying WANG Meisa LI Weiya JIANG Yuan YANG Fengkun

Tucatinib Breast cancer HER2 inhibitor FAERS database Adverse event Disproportionality method
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Visualization analysis on research progress and trends of Radix Bupleuri

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):639-648.
3020 times 663 times

ZHANG Xiuna FANG Jing TIAN Hui ZHAO Chaoyue YANG Yidi QU Fanna

Chinese medicinal materials Radix Bupleuri Bibliometrics Visualization analysis CiteSpace Network pharmacology Quality control
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Study on differences in inorganic element contents between raw and processed Rubia cordifolia

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):632-638.
2475 times 652 times

ZHAO Duanwei ZHANG Mingtong LIU Zhirong

Rubia cordifolia Processed products Multivariate statistical analysis Inorganic elements Hierarchical clustering analysis Principal component analysis Orthogonal partial least squares-discriminant analysis Inductively coupled plasma mass spectrometry
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Optimization of extraction process for total polyphenols from Uyghur medicinal material Ocimum basilicum L. seeds and evaluation of its in vitro antioxidant activity

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):624-631.
2853 times 685 times

WANG Lei WANG Fanhong CHEN Mo LI Zhen

Ocimum basilicum L. seeds Total polyphenols Ultrasonic-assisted extraction Orthogonal experiment Single-factor test DPPH ABTS Antioxidant activity
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Correlation study of ferulic acid and ligustilide levels with plant growth regulator residues in Angelica sinensis

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):613-623.
3109 times 710 times

ZHANG Shengjie MA Yantao ZHAO Shangyi JIA Jinru MA Xiao LI Donghua

Angelica sinensis Ferulic acid Ligustilide Plant growth regulator Residues Dose-effect relationship
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Analysis and evaluation of inorganic elements in Rhododendron anthopogonoides Maxim. from different regions

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):603-612.
2530 times 638 times

XU Sisi ZHANG Rui WANG Kefeng FAN Minxia TIAN Yongqiang

Rhododendron anthopogonoides Maxim. Inorganic elements ICP-AES ICP-MS FAAS
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Comparative study of the pharmacokinetics of Abelmoschus manihot (L.) Medic. flowers in directly taken decoction pieces and traditional decoction pieces of hyperoside in normal and nephrotic syndrome rats

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):595-602.
2612 times 648 times

NIU Kailin LUO Heng ZHOU Jing BAI Xiaolu WEN Qing CHEN Chu WU Yan ZHANG Hong MENG Huix-in ZHANG Lei

Abelmoschus manihot (L.) Medic. Hyperoside Nephrotic syndrome Directly taken decoction pieces Traditional decoction pieces HPLC-QqQ/MS Pharmacokinetics Drug metabolism Rats
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Study on the material basis and mechanism of Gualou Xiebai Banxia decoction in promoting mitophagy to ameliorate myocardial hypoxia/reoxygenation injury

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):584-594.
2820 times 702 times

ZHU Jiaxuan SONG Xiansheng YANG Ziqi XIAN Leyao ZHOU Hua HE Fan HUANG Yufeng

Gualou Xiebai Banxia decoction Chrysoeriol Hypoxia/reoxygenation myocardial cell injury Mitophagy Apoptosis Caspase-3 Parkin FUNDC1
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Mechanism of bisphenol A regulating the immune microenvironment of atopic dermatitis through the BPA/HRH1 axis

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):575-583.
2544 times 578 times

LI Chunhua LIANG Qinghua FU Qinqin ZHAO Kaizheng LU Jun

Bisphenol A Atopic dermatitis Endocrine disruptor Immune microenvironment Histamine receptor H1 Lymphocyte-specific protein tyrosine kinase Platelet-activating factor receptor
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Target screening and efficacy evaluation of lotusine against pancreatic cancer: prediction based on network pharmacology and validation by animal experiments

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):566-574.
2630 times 777 times

QI Fei CHEN Qi

Lotusine Pancreatic cancer Network pharmacology Therapeutic targets Molecular docking Animal experiment GO functional enrichment analysis KEGG pathway enrichment analysis
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Mechanism of Gualou Xiebai decoction in treating myocardial infarction based on UPLC-Orbitrap-MS/MS and network pharmacology

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):555-565.
3033 times 769 times

YAN Muxian LAN Yikun ZHOU Yaliang TAN Wanchuang LIN Junjie

Gualou Xiebai decoction Myocardial infarction Network pharmacology Ul-tra-performance liquid chromatography-orbitrap tandem mass spectrometry Mechanism of action Active components Target prediction
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Mechanism of formulas containing the Astragali Radix-Anemarrhenae Rhizoma herb pair in treating chronic heart failure based on Apriori algorithm, network pharmacology, and molecular docking

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):541-554.
3304 times 767 times

ZHANG Mengqian PANG Jianying WANG Chaohui HOU Jiahao ZHANG Yajing LI Jing SONG Yongxing MA Donglai

Chronic heart failure Astragali Radix-Anemarrhenae Rhizoma Herb pair Apriori algorithm Network pharmacology Molecular docking
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Exploration and reflection on evidence-based medicine teaching for practical training of research capacity in medical undergraduates under the "five-dimensional" paradigm

Published on New Medicine 2026,36(4):479-486.
3740 times 778 times

LI Zhenxin WU Junru ZHUANG Quan YUAN Hong LU Yao CAI Jingjing

Clinical medicine undergraduates Evidence-based medicine Educational reform Research capability development Teaching model
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Research advances in metabolic reprogramming-mediated macrophage polarization in gout

Published on New Medicine 2026,36(4):471-478.
2846 times 787 times

LIU Xinru YAN Jin MA Jing LI Chunlei MAN Dafu LI Huilin DA Gula ZHAO Jing WANG Jing LI Hongbin HOU Yunxia WANG Yong

Gout Metabolic reprogramming Macrophage polarization Glycolysis
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Research advances in targeted protein degradation technologies

Published on New Medicine 2026,36(4):464-470.
3197 times 798 times

PI Chuan HAO Xuanrun XIAO Haiting LUO Xing ZHANG Qixiong

Targeted protein degradation Proteolysis targeting chimera Molecular glue Lysosome-targeting chimera Autophagy-targeting chimera Autophagosome-tethering compound
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