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Determination of three components in lysine vitamin B12 granules based on two-dimensional HPLC-MS

Published on Frontiers in Pharmaceutical Sciences 2026,30(6):996-1000.
3122 times 886 times

WANG Xiaohui LIU Yiqing YANG Chun GOU Qiongxin SHAN Rumeng WU Qi

Two-dimensional high-performance liquid chromatography-triple quadrupole mass spectrometry method Vitamin B12 Lysine hydrochloride Inositol Content determination
Details
Study on critical quality attributes of carboxymethylcellulose sodium and their effects on the release behavior of nimesulide sustained-release tablets

Published on Frontiers in Pharmaceutical Sciences 2026,30(6):989-995.
3097 times 875 times

TIAN Tian TAN Jingling JIANG Yan BI Yong LIU Yanyun

Carboxymethylcellulose sodium Particle size Viscosity Molecular weight Dissolution and release Model drug
Details
Safety investigation on elemental impurities based on packaging material replacement of Xiao'er Xiaoji Zhike oral liquid

Published on Frontiers in Pharmaceutical Sciences 2026,30(6):981-988.
2940 times 832 times

JIANG Mingyue WANG Yonggang CAO Jixiang ZHANG Wei FAN Jianwei SU Ruiqiang

Xiao'er Xiaoji Zhike oral liquid Content determination Medicinal composite film Elemental impurities Packaging material replacement
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Study on quality evaluation of Galium aparine L. from different producing areas based on UPLC characteristic fingerprint and content determination

Published on Frontiers in Pharmaceutical Sciences 2026,30(6):974-980.
3299 times 942 times

HE Jiaying PAN Liye LIN Han PAN Lishan LIANG Yongxin LI Guowei CHEN Xiangdong SUN Dongmei

Galium aparine L. UPLC characteristic fingerprint Content determination Quality evaluation PCA OPLS-DA
Details
Analysis of the changes in volatile components of different processed products of Cuscutae Semen based on electronic nose and GC-MS

Published on Frontiers in Pharmaceutical Sciences 2026,30(6):965-973.
3003 times 740 times

LI Xiaoyu XUE Jiannan WANG Teng TANG Siyang QI Bin

Cuscutae Semen Processed products Gas chromatography-mass spectrometry Electronic nose Volatile components
Details
Optimization of the preparation process for Jianpi Tiaotang pills based on the CRITIC method combined with Box-Behnken response surface methodology

Published on Frontiers in Pharmaceutical Sciences 2026,30(6):957-964.
3081 times 718 times

FU Rong SHI Wanwan DONG Lihua

Jianpi Tiaotang pills Preparation process CRITIC method Box-Behnken response surface methodology
Details
Study on the separation, purification and hematopoietic activity of Pelodiscus sinensis peptides

Published on Frontiers in Pharmaceutical Sciences 2026,30(6):951-956.
3294 times 759 times

LI Yizhen LIU Yanxin ZHANG Jinhua LIU Fei CHEN Lei DIAO Mengqi ZHANG Linjun ZHANG Yanyan

Pelodiscus sinensis peptides Separation Purification Hematopoietic activity
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Preliminary study on the chemical constituents and anti-gastric cancer activity of the underground parts of Ferula songarica Pall. ex Schult.

Published on Frontiers in Pharmaceutical Sciences 2026,30(6):942-950.
2877 times 713 times

CHANG Xiaotong ZHAO Yaqin QING Degang SHI Leiling PENG Dongge WANG Guoping LU Ning

Ferula songarica Pall. ex Schult. Chemical composition Spectral identification HGC-27 cells Anti-proliferative activity
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Improvement of skin lesions in DNFB-induced atopic dermatitis mice by downregulating Th2 immune response through topical application of propolis

Published on Frontiers in Pharmaceutical Sciences 2026,30(6):934-941.
3005 times 735 times

TANG Liu HUANG Xiao FANG Shasha

Atopic dermatitis Propolis Topical application Th2 immune response Skin barrier
Details
Anti‑fatigue effect of Hibiscus manihot L. and its potential mechanism based on network pharmacology

Published on Frontiers in Pharmaceutical Sciences 2026,30(6):920-933.
2986 times 773 times

DU Junxia ZHU Xiumin LIU Hualiang

Hibiscus manihot L. Anti-fatigue Weight loaded swimming test Network pharmacology Molecular docking Inflammatory response AKT1 HSP90AA1
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Study on the mechanism of action of the Shengjiang powder plus Huanglian decoction in diabetes based on network pharmacology and animal experiments

Published on Frontiers in Pharmaceutical Sciences 2026,30(6):910-919.
3228 times 832 times

LAN Xinjian DING Tao LIU Bo WANG Xin CHEN Biao QIN Jia FU Shuang

Shengjiang powder plus Huanglian decoction Network pharmacology Molecular docking Diabetes Tumor necrosis factor Epidermal growth factor receptor
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Study on the effect and mechanism of Polygoni Orientalis Fructus on nonalcoholic fatty liver disease based on network pharmacology and experimental validation

Published on Frontiers in Pharmaceutical Sciences 2026,30(6):901-909.
3125 times 868 times

GAO Shuchang HAN Danrui MA Donglai WANG Xiaona DUAN Xuhong

Polygoni Orientalis Fructus NAFLD Network pharmacology Molecular docking Signaling pathway Mechanism of action Zebrafish model Lipid metabolism
Details
SWOT analysis of artificial intelligence applied to standardized residency training and teaching in the department of stomatology

Published on Journal of Mathematical Medicine 2026,39(6):464-470.
2431 times 677 times

CHEN Zhijie HUANG Suying NONG Xiaolin

Artificial intelligence Standardized residency training Department of stomatology SWOT analysis
Details
Treatment of a patient with EGFR R776C and L858R compound mutation lung adenocarcinoma: a case report

Published on Journal of Mathematical Medicine 2026,39(6):458-463.
2663 times 750 times

MA Yanran HU Jing XIE Conghua

EGFR R776C mutation EGFR L858R mutation Non-small cell lung cancer Osimertinib Amivantamab
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Multiple sclerosis with isolated vertigo and nystagmus as the initial manifestation: a case report

Published on Journal of Mathematical Medicine 2026,39(6):454-457.
2457 times 631 times

LIANG Yun ZENG Xiaoyun ZHOU Jie XU Peng FENG Yufei

Multiple sclerosis Isolated vertigo Nystagmus Vestibular function test Clinically isolated syndrome
Details
The mechanism of silybin in treating against gastric cancer based on systematic network pharmacology analysis

Published on Journal of Mathematical Medicine 2026,39(6):445-453.
2193 times 740 times

MI Jiali SHI Lei WANG Lina WU Chaocai

Silybin Gastric cancer Network pharmacology PI3K/AKT signaling pathway Cell proliferation Cell migration Mechanism
Details
Bibliometric analysis of PIK3CA gene mutations in metastatic colorectal cancer research based on the Web of Science database

Published on Journal of Mathematical Medicine 2026,39(6):436-444.
2382 times 689 times

LI Jianwen LIU Gang HAO Liang

Metastatic colorectal cancer PIK3CA CiteSpace Web of Science Bibliometrics Visualization analysis
Details
The mechanism of Huanglian Jiedu Decoction in the treatment of acute mastitis with blazing heat-toxin pattern based on network pharmacology and molecular docking

Published on Journal of Mathematical Medicine 2026,39(6):426-435.
2680 times 773 times

WANG Lingling ZHANG Shengliang FENG Xuan ZHAO Changwei LI Yantao

Huanglian Jiedu Decoction Acute mastitis Blazing heat-toxin pattern Network pharmacology Molecular docking Mechanism
Details
Visual analysis of hotspots and trends in vascular parkinsonism based on CiteSpace

Published on Journal of Mathematical Medicine 2026,39(6):417-425.
2239 times 681 times

YU Ziru ZHANG Peng XU Junfeng

Vascular parkinsonism CiteSpace Visual analysis Bibliometrics
Details
Bibliometric analysis of the association between lipid metabolism and non-alcoholic fatty liver disease

Published on Journal of Mathematical Medicine 2026,39(6):406-416.
2409 times 738 times

LUO Yue PENG Yuanjun AO Na LI Zhihang XIAO Tingfen CAO Jun FU Liying WANG Zhiqi XU Fei

Lipid metabolism Non-alcoholic fatty liver disease CiteSpace VOSviewer Bibliometrics
Details