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Klinefelter syndrome with diabetes ketoacidosis as the first manifestation: a case report and literature analysis

Published on Journal of Mathematical Medicine 2026,39(4):314-318.
772 times 173 times

LIU Xiaoyu YANG Fan WU Jing YIN Wanling

Klinefelter syndrome Hypogonadism Gynecomastia Diabetic ketoacidosis Osteoporosis
Details
Fertility-sparing treatment for ovarian yolk sac tumor in a woman of childbearing age: a case report

Published on Journal of Mathematical Medicine 2026,39(4):307-313.
801 times 185 times

HE Li CHEN Yuyan WEI Yi ZHANG Fan

Ovarian yolk sac tumor Ovarian malignant germ cell tumor Childbearing age Fertility-sparing treatment
Details
Hemostatic management during the perioperative period in a patient with severe hemophilia A and high-titer FⅧ inhibitors: a case report

Published on Journal of Mathematical Medicine 2026,39(4):301-306.
783 times 165 times

WANG Ziqing ZHANG Xian

Hemophilia A Factor Ⅷ inhibitor Recombinant activated factor Ⅶ Os-teofascial Compartment syndrome
Details
Research progress of traditional Chinese medicine on the regulation of Notch signaling pathway in the treatment of rheumatoid arthritis

Published on Journal of Mathematical Medicine 2026,39(4):294-300.
984 times 199 times

LI Mingxia CHEN Junlong HE Bianqiang HE Wenkui GAO Wanpeng

Rheumatoid arthritis Notch signaling pathway Traditional Chinese medicine Mechanism
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Influencing factors of healthcare-seeking delay for pulmonary tuberculosis pa-tients in China from 2014 to 2024: a Meta-analysis

Published on Journal of Mathematical Medicine 2026,39(4):282-293.
983 times 187 times

HUANG Chen AN Xuemei YANG Tingyu HONG Zhongxi LUO Yongyuan XIONG Xiya ZHOU Xianyu

Tuberculosis Healthcare-seeking delay Influencing factors Meta-analysis
Details
Efficacy analysis of extended curettage combined with denosumab adjuvant therapy for giant cell tumor of the bone

Published on Journal of Mathematical Medicine 2026,39(4):273-281.
838 times 157 times

WEN Riyou LE Guoping

Giant cell tumor of the bone Extended curettage Denosumab Relapse rate
Details
A study on the mechanisms regulation of BIRC5 expression in prostate cancer and its potential targeted therapy

Published on Journal of Mathematical Medicine 2026,39(4):263-272.
812 times 207 times

YE Junjie CHEN Yunyi HUANG Yingxin LI Yanliang WANG Huifeng

Carcinoma of prostate BIRC5 gene Targeted therapy Mechanism
Details
SERPINE1 affects the metastasis of colon cancer by regulating MMP-9 and MMP-2

Published on Journal of Mathematical Medicine 2026,39(4):252-262.
788 times 171 times

CHEN Dehe DING Pengpeng LI Wending LI Hongtao

Colon cancer SERPINE1 MMP-9 MMP-2 Metastasis
Details
Bibliometric analysis of the research status, hotspots and trends in the field of prescription comment in China

Published on Journal of Mathematical Medicine 2026,39(4):241-251.
969 times 208 times

YUAN Jiachen YU Lu CHEN Yuqin

Prescription comment Bibliometrics CiteSpace VOSviewer Hotspots Trends
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Discussion on the field practice teaching mode of medicinal botany based on the orientation of scientific research innovation practice

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):715-720.
847 times 166 times

CHEN Peng PENG Yansong CHEN Fuchao HE Jingsheng ZOU Youquan TANG Jun LIU Gang ZHOU Benhong

Medicinal botany Field practice Innovative practice Digital intelligence technology Ethnic medicine Teaching assessment Talent cultivation
Details
Design and application scenarios of digital monitoring model for online drug sales——based on Shanghai online drug circulation supervision system

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):707-714.
887 times 191 times

ZHUANG Wenyi ZHAO Yuxiang FENG Xiao SHEN Kan WANG Haibo GUO Aiwei ZHOU Fengwu WANG Guangping

Drug Online Circulation Digitalization Monitoring Robotic process automation Case Investigation and Handling Database
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Research progress on the relationship between vitamin D and pediatric sepsis

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):699-706.
809 times 161 times

ZHU Liran XIA Wenwen WANG Zhen CUI Wei CAI Ming LIU Haipeng

Pediatric sepsis Vitamin D 25-hydroxyvitamin D3 Immune regulation Inflammatory response Clinical outcomey
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Research progress on the hepatoprotective effects and safety evaluation of sophocarpine

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):692-698.
775 times 140 times

JIANG Jingjing WANG Changlin SONG Chunhong LI Yanan

Sophocarpine Hepatoprotective effect Safety evaluation Lipid metabolism An-ti-fibrosis Anti-inflammatory Anti-tumor Hepatotoxicity Acute toxicity
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Research progress on therapeutic strategies and mechanisms of action of traditional Chinese medicines with “medicine-food homology” in the prevention and treatment of chemo-therapy-induced myelosuppression

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):679-691.
1017 times 203 times

CHEN Weishi LI Jing LI Jing HAN Tao

Chemotherapy-induced myelosuppression Medicine-food homology Etiology and pathogenesis Treatment strategies Characteristics of traditional Chinese medicine Active ingredients Mechanism of action Medullary hematopoiesis
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Research progress on chemical components and pharmacological effects of Anisi Stellati Fructus

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):668-678.
909 times 172 times

YU Ran DI Qing SUN Guyue ZHAO Xiangxuan

Anisi Stellati Fructus Chemical components Pharmacological effect Immune regulation Antioxidation Flavonoids Antibacterial Antitumor
Details
Investigation and analysis on the current status of high-alert medications management and pharmacists’ cognition in medical institutions in Hubei Province

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):657-667.
740 times 177 times

RONG Xinyi LI Wei ZHANG Chengliang YU Zaoqin

High-alert medications Pharmacist Management status Cognitive level Influencing factors
Details
Adverse event signal mining and analysis of tucatinib based on the FAERS database

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):649-656.
849 times 188 times

ZHAO Jun ZHAO Zhenying WANG Meisa LI Weiya JIANG Yuan YANG Fengkun

Tucatinib Breast cancer HER2 inhibitor FAERS database Adverse event Disproportionality method
Details
Visualization analysis on research progress and trends of Radix Bupleuri

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):639-648.
979 times 202 times

ZHANG Xiuna FANG Jing TIAN Hui ZHAO Chaoyue YANG Yidi QU Fanna

Chinese medicinal materials Radix Bupleuri Bibliometrics Visualization analysis CiteSpace Network pharmacology Quality control
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Study on differences in inorganic element contents between raw and processed Rubia cordifolia

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):632-638.
842 times 209 times

ZHAO Duanwei ZHANG Mingtong LIU Zhirong

Rubia cordifolia Processed products Multivariate statistical analysis Inorganic elements Hierarchical clustering analysis Principal component analysis Orthogonal partial least squares-discriminant analysis Inductively coupled plasma mass spectrometry
Details
Optimization of extraction process for total polyphenols from Uyghur medicinal material Ocimum basilicum L. seeds and evaluation of its in vitro antioxidant activity

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):624-631.
930 times 233 times

WANG Lei WANG Fanhong CHEN Mo LI Zhen

Ocimum basilicum L. seeds Total polyphenols Ultrasonic-assisted extraction Orthogonal experiment Single-factor test DPPH ABTS Antioxidant activity
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