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Optimization of extraction process for total polyphenols from Uyghur medicinal material Ocimum basilicum L. seeds and evaluation of its in vitro antioxidant activity

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):624-631.
1992 times 433 times

WANG Lei WANG Fanhong CHEN Mo LI Zhen

Ocimum basilicum L. seeds Total polyphenols Ultrasonic-assisted extraction Orthogonal experiment Single-factor test DPPH ABTS Antioxidant activity
Details
Correlation study of ferulic acid and ligustilide levels with plant growth regulator residues in Angelica sinensis

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):613-623.
2020 times 417 times

ZHANG Shengjie MA Yantao ZHAO Shangyi JIA Jinru MA Xiao LI Donghua

Angelica sinensis Ferulic acid Ligustilide Plant growth regulator Residues Dose-effect relationship
Details
Analysis and evaluation of inorganic elements in Rhododendron anthopogonoides Maxim. from different regions

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):603-612.
1786 times 384 times

XU Sisi ZHANG Rui WANG Kefeng FAN Minxia TIAN Yongqiang

Rhododendron anthopogonoides Maxim. Inorganic elements ICP-AES ICP-MS FAAS
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Comparative study of the pharmacokinetics of Abelmoschus manihot (L.) Medic. flowers in directly taken decoction pieces and traditional decoction pieces of hyperoside in normal and nephrotic syndrome rats

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):595-602.
1818 times 396 times

NIU Kailin LUO Heng ZHOU Jing BAI Xiaolu WEN Qing CHEN Chu WU Yan ZHANG Hong MENG Huix-in ZHANG Lei

Abelmoschus manihot (L.) Medic. Hyperoside Nephrotic syndrome Directly taken decoction pieces Traditional decoction pieces HPLC-QqQ/MS Pharmacokinetics Drug metabolism Rats
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Study on the material basis and mechanism of Gualou Xiebai Banxia decoction in promoting mitophagy to ameliorate myocardial hypoxia/reoxygenation injury

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):584-594.
1972 times 451 times

ZHU Jiaxuan SONG Xiansheng YANG Ziqi XIAN Leyao ZHOU Hua HE Fan HUANG Yufeng

Gualou Xiebai Banxia decoction Chrysoeriol Hypoxia/reoxygenation myocardial cell injury Mitophagy Apoptosis Caspase-3 Parkin FUNDC1
Details
Mechanism of bisphenol A regulating the immune microenvironment of atopic dermatitis through the BPA/HRH1 axis

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):575-583.
1780 times 392 times

LI Chunhua LIANG Qinghua FU Qinqin ZHAO Kaizheng LU Jun

Bisphenol A Atopic dermatitis Endocrine disruptor Immune microenvironment Histamine receptor H1 Lymphocyte-specific protein tyrosine kinase Platelet-activating factor receptor
Details
Target screening and efficacy evaluation of lotusine against pancreatic cancer: prediction based on network pharmacology and validation by animal experiments

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):566-574.
1777 times 491 times

QI Fei CHEN Qi

Lotusine Pancreatic cancer Network pharmacology Therapeutic targets Molecular docking Animal experiment GO functional enrichment analysis KEGG pathway enrichment analysis
Details
Mechanism of Gualou Xiebai decoction in treating myocardial infarction based on UPLC-Orbitrap-MS/MS and network pharmacology

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):555-565.
2017 times 521 times

YAN Muxian LAN Yikun ZHOU Yaliang TAN Wanchuang LIN Junjie

Gualou Xiebai decoction Myocardial infarction Network pharmacology Ul-tra-performance liquid chromatography-orbitrap tandem mass spectrometry Mechanism of action Active components Target prediction
Details
Mechanism of formulas containing the Astragali Radix-Anemarrhenae Rhizoma herb pair in treating chronic heart failure based on Apriori algorithm, network pharmacology, and molecular docking

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):541-554.
2310 times 526 times

ZHANG Mengqian PANG Jianying WANG Chaohui HOU Jiahao ZHANG Yajing LI Jing SONG Yongxing MA Donglai

Chronic heart failure Astragali Radix-Anemarrhenae Rhizoma Herb pair Apriori algorithm Network pharmacology Molecular docking
Details
Exploration and reflection on evidence-based medicine teaching for practical training of research capacity in medical undergraduates under the "five-dimensional" paradigm

Published on New Medicine 2026,36(4):479-486.
2814 times 483 times

LI Zhenxin WU Junru ZHUANG Quan YUAN Hong LU Yao CAI Jingjing

Clinical medicine undergraduates Evidence-based medicine Educational reform Research capability development Teaching model
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Research advances in metabolic reprogramming-mediated macrophage polarization in gout

Published on New Medicine 2026,36(4):471-478.
1758 times 494 times

LIU Xinru YAN Jin MA Jing LI Chunlei MAN Dafu LI Huilin DA Gula ZHAO Jing WANG Jing LI Hongbin HOU Yunxia WANG Yong

Gout Metabolic reprogramming Macrophage polarization Glycolysis
Details
Research advances in targeted protein degradation technologies

Published on New Medicine 2026,36(4):464-470.
1747 times 483 times

PI Chuan HAO Xuanrun XIAO Haiting LUO Xing ZHANG Qixiong

Targeted protein degradation Proteolysis targeting chimera Molecular glue Lysosome-targeting chimera Autophagy-targeting chimera Autophagosome-tethering compound
Details
Association between oxygenation status and pressure injury in intensive care unit patients: a Meta-analysis

Published on New Medicine 2026,36(4):457-463.
1358 times 452 times

DONG Pingping LIU Fangfang CAO Hunan

Pressure injury Intensive care unit Arterial partial pressure of oxygen Meta-Analysis
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Recurrence rate and influencing factors of benign paroxy-smal positional vertigo after repositioning of otolith: a Meta-analysis

Published on New Medicine 2026,36(4):448-456.
2818 times 529 times

WANG Rongrong MU Shuyue WANG Xiangnan ZHUANG Yaqi QIU Wenling QU Guiyu

Benign paroxy-smal positional vertigo Otolith Recurrence Influencing factor Meta-analysis
Details
Single-nucleus transcriptomics reveals subtypes-specific cellular and molecular features of cardiomyopathy

Published on New Medicine 2026,36(4):438-447.
1466 times 562 times

JU Yingjiao YAO Jingyi ZHANG Song MIN Li

Cardiomyopathy Hypertrophic cardiomyopathy Dilated cardiomyopathy Ar-rhythmogenic cardiomyopathy Single-nucleus RNA sequencing
Details
Disease burden of metabolic dysfunction-associated steatotic liver disease in the elderly population globally and in China from 1990 to 2021

Published on New Medicine 2026,36(4):428-437.
1815 times 559 times

ZHANG Qiang ZHAO Xiaoxiao WANG Haibo XU Peng WANG Yaxing ZHAO Xinke LIU Fan LI Jiali HE Tao CHEN Zhengtao Ding Yunhan KE Lixin LI Jieyun XUN Yangqin LU Cuncun

Metabolic dysfunction-associated steatotic liver disease Non-alcoholic fatty liver disease Older adult Disease burden Prediction model
Details
The effect of TRIM7 on lipid accumulation in foam cells in atherosclerosis

Published on New Medicine 2026,36(4):421-427.
1318 times 548 times

ZHAO Yilin HOU Bowen CAI Zeming YANG Yi ZHU Lihua

Foam cells E3 ubiquitin-protein ligase TRIM7 Atherosclerosis
Details
Application of intelligent information management in the efficiency of referral for abnormal physical examination results

Published on New Medicine 2026,36(4):414-420.
1779 times 607 times

LI Jianqi TANG Biao LI Xin CHEN Jun JIANG Jie

Intelligent information management Physical examination Important abnormal results Timely referral rate Medical quality
Details
Construction of a predictive model for asymptomatic venous thromboembolism in patients with ovarian clear cell carcinoma after surgery

Published on New Medicine 2026,36(4):407-413.
1430 times 598 times

REN Hang WANG Hua CAI Hongbing

Ovarian clear cell carcinoma Venous thromboembolism Nomograms Prognosis
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Construction of a risk prediction model for fertility anxiety in female thyroid cancer patients of reproductive age

Published on New Medicine 2026,36(4):399-406.
1624 times 638 times

PENG Jingjun PENG Yuxia ZHANG Wenling HONG Xiaoting LI Yuyu

Reproductive age Thyroid cancer Fertility anxiety Risk prediction model
Details