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Efficacy evaluation and quality of life analysis of cadonilimab combined with bevacizumab biosimilar and chemotherapy in the treatment of metastatic colorectal cancer

Published on Frontiers in Pharmaceutical Sciences 2026,30(9):1538-1548.
648 times 167 times

ZHANG Xiaoqing LIU Shuai ZHANG Kai HE Jing WANG Yuchao ZHANG Juan LUAN Wei

Cadonilimab Bevacizumab Metastatic colorectal cancer Efficacy evaluation RAS-mutated Progression-free survival Objective response rate Disease control rate
Details
Simultaneous determination of principal component and disodium edetate in azelastine hydrochloride nasal spray by dual-wavelength HPLC

Published on Frontiers in Pharmaceutical Sciences 2026,30(9):1532-1537.
628 times 189 times

LUO Xiaolei LI Yitong QIN Li

HPLC Nasal spray Azelastine hydrochloride Disodium edetate Content determination
Details
Determination of related substances and enantiomer in active pharmaceutical ingredient of rotigotine by HPLC

Published on Frontiers in Pharmaceutical Sciences 2026,30(9):1523-1531.
639 times 158 times

WANG Weijiao CHEN Hongyu TANG Haozheng TIAN Jialin ZHAO Shiye TONG Ming

HPLC Rotigotine Related substances Enantiomer Method validation
Details
Qualitative and quantitative analysis of chemical constituents of Mori Cortex and its adulterant Mori Cathayanae Cortex

Published on Frontiers in Pharmaceutical Sciences 2026,30(9):1514-1522.
646 times 167 times

LYU Pan ZHANG Fei LI Lin HOU Junjie XIAO Ling

Mori Cortex Mori Cathayanae Cortex Chemical constituents UPLC-Q-TOF-MS/MS UPLC-QqQ-MS/MS
Details
Comparative analysis of metabolite differences in Rehmannia glutinosa and Helianthus tuberosus before and after steaming based on widely targeted metabolomics

Published on Frontiers in Pharmaceutical Sciences 2026,30(9):1502-1513.
681 times 212 times

SHEN Guoxi LI Chao LI Mengzhi ZHANG Chaoyun

Rehmannia glutinosa Helianthus tuberosus Steaming Widely targeted metabolomics Metabolites
Details
Study on the preparation of liposomal thermosensitive gel of leech extract

Published on Frontiers in Pharmaceutical Sciences 2026,30(9):1492-1501.
637 times 175 times

ZHAO Shuqi WU Jinhao YANG Sinan JIANG Qiwen LIU Huashi

Leech extract Liposome Thermosensitive gel Film dispersion method Orthogonal test Lecithin Cholesterol
Details
Study on acute toxicity of Huangqi Yangxue Tiaojing formula in SD rats

Published on Frontiers in Pharmaceutical Sciences 2026,30(9):1484-1491.
671 times 178 times

ZHAO Cui YUE Bin WU Quansheng CHEN Yuanhuan CHU Cuijun LI Minglan XU Xiaojuan

Huangqi Yangxue Tiaojing formula Rats Acute toxicity test Maximum tolerated dose
Details
Exploration of the potential mechanism of Zhuling decoction in the intervention of diabetic kidney disease based on network pharmacology, molecular docking and molecular dynamics simulation

Published on Frontiers in Pharmaceutical Sciences 2026,30(9):1469-1483.
686 times 186 times

CHEN Jiaqi WU Binxin LING Kai'en

Zhuling decoction Diabetic kidney disease Network pharmacology PI3K-Akt signaling pathway
Details
Study on the action mechanism of Herba Verbenae-Campsis Flos herb pair in treating thyroid nodules based on network pharmacology and molecular docking

Published on Frontiers in Pharmaceutical Sciences 2026,30(9):1457-1468.
732 times 210 times

LI Chang GAO Shuchang HAN Danrui DUAN Xuhong

Thyroid nodules Herba Verbenae-Campsis Flos herb pair Network pharmacology Molecular docking Signaling pathway Mechanism of action
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Exploring the molecular mechanisms ofScutellaria radixin treating lung cancer based on network pharmacology and molecular docking

Published on Frontiers in Pharmaceutical Sciences 2026,30(9):1445-1456.
3514 times 465 times

QU Jianwen ZHAO Xiangxuan XU Shu

Scutellaria radix Network pharmacology Network targets Lung cancer Mechanism of action Molecular docking
Details
Application of self-organised learning environments integrated with generative artificial intelligence teaching mode in the standardized training of residents

Published on Journal of Mathematical Medicine 2026,39(9):701-706.
613 times 160 times

LUO Haiping FENG Wenle YU Hongmin

Self-organised learning environments Generative artificial intelligence Standardized training of residents Digital literacy Teaching effectiveness Satisfaction
Details
Construction and practice of "Pharmaceutical Analysis" AI curriculum based on knowledge map

Published on Journal of Mathematical Medicine 2026,39(9):693-700.
664 times 220 times

LIU Zheng DENG Tao YANG Bin ZHENG Zhaoguang LUO Wenhui XU Dongsheng SUN Pinghua GUO Jialiang ZENG Xuxin

Pharmaceutical analysis Knowledge map Artificial intelligence Pharmacy Course construction
Details
Recurrent giant retroperitoneal liposarcoma: a case report

Published on Journal of Mathematical Medicine 2026,39(9):686-692.
557 times 200 times

GUO Xionghao XIAO Fei

Retroperitoneal liposarcoma Local recurrence Diagnosis Pathological characteristics Treatment Neurological dysfunction
Details
Advances in the application of digital intelligence technology in nutritional management for patients with hypertension

Published on Journal of Mathematical Medicine 2026,39(9):679-685.
564 times 146 times

WANG Zeyu GAO Xiaoyun LIU Siyu SUN Junyi FENG Huiling

Digital intelligence technology Hypertension Nutritional management Review Nursing
Details
Research progress of neutrophil extracellular traps in ischemic heart disease

Published on Journal of Mathematical Medicine 2026,39(9):670-678.
614 times 212 times

ZHOU Yuqing GAO Jin GUO Jing CHEN Hao

Neutrophil extracellular traps Ischemic heart disease Myocardial infarction Inflammation Immunothrombosis
Details
Analysis of the current status of awareness and weak links of clinical nurses' knowledge on artificial liver vascular access maintenance

Published on Journal of Mathematical Medicine 2026,39(9):664-669.
605 times 198 times

CHENG Xuebing ZHENG Jing GAO Haibing

Artificial liver Vascular access Awareness Nurse Cross-sectional study
Details
Exploring the impact of benzo[a]pyrene exposure on allergic asthma based on network toxicology and molecular docking

Published on Journal of Mathematical Medicine 2026,39(9):654-663.
582 times 228 times

LI Daoyuan HUANG Yuli WANG Zhen REN Cailing

Benzo[a]pyrene Allergic asthma Network toxicology Molecular docking Respiratory toxicity
Details
Bibliometric analysis of immunotherapy resistance in colorectal cancer based on Web of Science database

Published on Journal of Mathematical Medicine 2026,39(9):645-653.
612 times 218 times

LI Jianwen LIU Jinxin WEI Zhaoyi

Colorectal Cancer Immunotherapy Resistance Bibliometrics Web of Science CiteSpace VOSviewer Visualization analysis
Details
Data mining on the minocycline-related pigmentation adverse events based on the FAERS database

Published on Journal of Mathematical Medicine 2026,39(9):637-644.
620 times 192 times

ZHANG Weiwei ZHAO Xin TIAN Wei LIU Nannan

Minocycline Adverse drug event Pigmentation FAERS database Data mining Reporting odds ratio method
Details
Analysis of the unqualified items in the quality management system of Wuhu Blood Center from 2021 to 2025

Published on Journal of Mathematical Medicine 2026,39(9):629-636.
613 times 206 times

YANG Xu CHEN Chiyu WU Jie HUANG Hui CHEN Xiulan JIANG Qingqing CAO Shiyi

Blood Center Quality management system Unqualified items Health management
Details