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Identification of safety signals for antiepileptic drug-associated thrombocytopenia in minor population utilizing the FAERS database

Published on Frontiers in Pharmaceutical Sciences 2026,30(7):1196-1204.
2107 times 520 times

DUAN Difan CHEN Yan LIN Gaoyang QIAN Mengying SHAN Qing GUO Jinmin

Thrombocytopenia Antiepileptic drugs Minor population Food and Drug Administration Adverse Event Reporting System Adverse drug event Signal mining
Details
Simultaneous determination of 4 anti-infective drug concentrations in human plasma by LC-MS/MS

Published on Frontiers in Pharmaceutical Sciences 2026,30(7):1187-1195.
1997 times 498 times

FU Yao QIAN Zhengyue AO Hui CAO Jianfeng LI Jing

Liquid chromatography-tandem mass spectrometry Plasma drug concentration Imipenem Meropenem Posaconazole Colistin E Therapeutic drug monitoring
Details
Assessment of the impact of continuous renal replacement therapy on imipenem pharmacokinetics and clinical efficacy in critically ill patients via therapeutic drug monitoring

Published on Frontiers in Pharmaceutical Sciences 2026,30(7):1178-1186.
2290 times 554 times

ZHANG Li CHEN Yuan HU Miao WAN Panting LIU Pingyu

Imipenem Continuous renal replacement therapy Therapeutic drug monitoring Pharmacokinetics/pharmacodynamics Individualized dosing
Details
Validation of virus inactivation/removal efficacy in production process of transfer factor solution

Published on Frontiers in Pharmaceutical Sciences 2026,30(7):1170-1177.
2055 times 510 times

XUE Meiling GUO Weizhen WANG Hongxin WANG Chuanli CHEN Meihong WEI Xiaoliang

Transfer factor solution Virus inactivation Virus removal Pasteurization Ultrafiltration membrane filtration method
Details
Determination of 6 components in compound asiatic moonseed, paracetamol, and chlorphenamine maleate tablets by SPE-HPLC

Published on Frontiers in Pharmaceutical Sciences 2026,30(7):1163-1169.
2042 times 554 times

QIAN Yujuan XIAO Honghua YUN Xiaofei HAN Feng ZHANG Yanxia YAN Zeman

Solid-phase extraction HPLC Compound asiatic moonseed paracetamol and chlorphenamine maleate tablets Quality control
Details
Stability analysis of compound menthol nasal drops under different packaging materials and storage conditions

Published on Frontiers in Pharmaceutical Sciences 2026,30(7):1155-1162.
2066 times 544 times

WANG Qiulan HAN Hong CAI Yue XIONG Wei XIE Xuejia

Compound menthol nasal drops Packaging materials Storage conditions Gas chromatography Camphor Menthol Statistical analysis
Details
Mechanistic study on chitosan-mediated adsorption for regulating the migration of lead and cadmium in an eczema external wash formula

Published on Frontiers in Pharmaceutical Sciences 2026,30(7):1147-1154.
2005 times 575 times

ZHI Hui WANG Zhonghua LIU Xixian

Eczema external wash formula Heavy metals Pb Cd Adsorption Removal Migration
Details
Optimization of integrated processing technology for Acorus tatarinowii production area based on Box-Behnken response surface methodology combined with CRITIC method

Published on Frontiers in Pharmaceutical Sciences 2026,30(7):1139-1146.
2224 times 607 times

WU Shengzhen ZHANG Yu WU Xiangwei SONG Lifang WU Suzhen

Acorus tatarinowii Integrated production and processing Processing CRITIC method Box-Behnken design-response surface methodology
Details
Determination of multiple mutagenic impurities in rotigotine by LC-MS/MS and GC-MS

Published on Frontiers in Pharmaceutical Sciences 2026,30(7):1132-1138.
2077 times 574 times

WANG Weijiao TANG Haozheng TIAN Jialin CHEN Hongyu

Rotigotine Mutagenic impurities p-toluenesulfonate esters 1-iodopropane LC-MS/MS GC-MS
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Establishment of a UPLC fingerprint and multi-component quantitation method for Lycii Fructus

Published on Frontiers in Pharmaceutical Sciences 2026,30(7):1123-1131.
2199 times 651 times

LUO Qun JIN Hongyu LI Wei WANG Ying LIN Yongqiang

Lycii Fructus Fingerprint Content determination Rutin Kaempferol-3-O-rutinoside Narcissin Principal component analysis Hierarchical cluster analysis
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Optimization of flavonoid extraction conditions from Polygonatum cyrtonema by orthogonal test combined with particle swarm optimization and distribution patterns in different organs

Published on Frontiers in Pharmaceutical Sciences 2026,30(7):1112-1122.
2163 times 600 times

SHEN Yuan LIANG Qiao PAN Wenyun LI Chunxiao LI Keying ZHANG Xianwen ZHONG Junfang FAN Baolei

Polygonatum cyrtonema Flavonoids Particle swarm optimization algorithm HPLC Principal component analysis Cluster analysis Spearman correlation analysis
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Effects of decitabine and DNMT1 silencing on the expression and methylation of LINC00472 in osteosarcoma MG-63 cells

Published on Frontiers in Pharmaceutical Sciences 2026,30(7):1102-1111.
2050 times 609 times

ZOU Qiong YANG Yanming REN Danyang TU Caixia SHEN Jianling GAO Lihui LI Fashuang ZHANG Lilin LI Huiying

LINC00472 Decitabine DNMT1 Methylation Osteosarcoma MG-63 cells
Details
Preliminary analysis of the multi-index components determination and antitussive mechanism of Kelu oral liquid by HPLC and network pharmacology

Published on Frontiers in Pharmaceutical Sciences 2026,30(7):1092-1101.
2278 times 623 times

HE Jingxia XU Gang ZHANG Xiaoxiao GONG Deling LIU Yangyang WANG Xiaomei

Kelu oral liquid Network pharmacology Antitussive Multi-index components HPLC Mechanism
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Mechanism study of glycyrrhizin in the treatment of oral squamous cell carcinoma based on network pharmacology and in vitro cell experiments

Published on Frontiers in Pharmaceutical Sciences 2026,30(7):1081-1091.
2221 times 700 times

TIAN Zhongjia LEI Yintao LI Junfu WANG Qian

Glycyrrhizin Oral squamous cell carcinoma Network pharmacology Molecular docking Notch signaling pathway
Details
Construction and practice of AI-enabled online medical humanities courses: a case study of the national first-class undergraduate course "doctor-patient communication"

Published on New Medicine 2026,36(7):834-840.
1821 times 487 times

ZHU Binghua JIANG Zhenzhen CHEN Xiao HU Yingying

Artificial intelligence Medical humanities education Online course Doctor-patient communication Course construction Teaching reform
Details
Implementation of a mind map-driven flipped classroom approach in "physical diagnostics" instruction for the biological engineering major

Published on New Medicine 2026,36(7):827-833.
1360 times 433 times

ZHANG Zhongying YANG Wei WEI Zhanyun ZHANG Li LUO Hongyu ZHANG Shengdian

Mind map Flipped classroom Medical education Physical diagnostics
Details
The application progress of DNA methylation detection in cervical cancer screening

Published on New Medicine 2026,36(7):821-826.
1879 times 481 times

YI Siyu WANG Fen

Cervical cancer DNA methylation Human papilloma virus screening Risk triage Cervical intraepithelial neoplasia
Details
Recent advances in the diagnosis and treatment of neovascular glaucoma

Published on New Medicine 2026,36(7):814-820.
2665 times 492 times

YE Zhouyang ZHENG Tian LIANG Ruyu JIANG Mengyu CHEN Xiaomin KE Min

Neovascular glaucoma Anti-vascular endothelial growth factor Panretinal photocoagnlation Treatment
Details
Evaluation of methodological quality of clinical practice guidelines on female urinary incontinence

Published on New Medicine 2026,36(7):806-813.
1535 times 458 times

LIU Lu WANG Moran CHEN Chuanrong LI Yahui HE Bolin SHEN Lingyu

Female urinary incontinence Clinical practice guidelines Appraisal of Guidelines for Research and Evaluation Ⅱ Quality evaluation
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Influencing factors of motor function recovery in patients with traumatic brain injury: a Meta-analysis

Published on New Medicine 2026,36(7):798-805.
2048 times 458 times

LI Yujie JIA Yao ZHANG Lating LI Sitong JIANG Xue

Traumatic brain injury Brain injury Motor function Influencing factors Meta-analysis
Details