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Bleeding risk prediction models for non-valvular atrial fibrillation patients taking new oral anticoagulants: a systematic review

Published on Chinese Journal of Pharmacoepidemiology 2025,34(12):1413-1422.
2234 times 484 times

ZHANG Huichao YAN Shenghua TIAN Bei

Non-valvular atrial fibrillation New oral anticoagulants Bleeding Prediction model Systematic review
Details
Sophoricoside inhibits hepatic ischemia-reperfusion injury by promoting AMPK activation

Published on Chinese Journal of Pharmacoepidemiology 2025,34(12):1399-1412.
2126 times 482 times

LI Xinyan ZHANG Yonghui DONG Xinran ZHANG Xiaojing LI Kun

Hepatic ischemia-reperfusion injury Sophoricoside AMP-activated protein kinase Inflammation Apoptosis
Details
Retrospective analysis of immune checkpoint inhibitor-induced colitis

Published on Chinese Journal of Pharmacoepidemiology 2025,34(12):1390-1398.
2293 times 470 times

SONG Jialin WU Lei WANG Yiting

Immune checkpoint inhibitors Drug-induced colitis Immunotherapy toxicity Risk factors Retrospective analysis
Details
Effects of statins on sepsis-associated delirium in critically ill patients:

Published on Chinese Journal of Pharmacoepidemiology 2025,34(12):1373-1381.
2075 times 494 times

a retrospective cohort study based on the MIMIC-IV database

Statin Sepsis Delirium Critical care MIMIC-IV database
Details
A multicenter, phase IV, randomized controlled trial of Relinqing granules in treating female acute uncomplicated urinary tract infection (damp heat in the lower jiao pattern)

Published on Chinese Journal of Pharmacoepidemiology 2025,34(12):1363-1372.
2516 times 650 times

XIE Weiji GAO Zhan HUANG Ling ZHANG Liyan

Relinqing granules Uncomplicated urinary tract infection Damp heat in the lower jiao pattern Ciprofloxacin hydrochloride Randomized controlled trial Non-inferiority clinical trial
Details
Guide on Methodological Standards in Pharmacoepidemiology (2nd edition) and their series interpretation (12): applications of negative control methods and case analysis

Published on Chinese Journal of Pharmacoepidemiology 2025,34(12):1353-1362.
2228 times 558 times

JIANG Baoyuan ZHAN Siyan SUN Feng YANG Zhirong WU Shanshan

Pharmacoepidemiology Methodology Guidelines Negative controls Unmeasured confounding
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Development and reliability evaluation of a medication safety literacy scale for elderly patients with chronic conditions

Published on Chinese Journal of Pharmacoepidemiology 2026,35(1):75-82.
3081 times 653 times

WANG Fang WANG Fengjuan WANG Wenbo LIU Huijuan

Medication safety literacy Chronic diseases Elderly patients Reliability Validity Scale
Details
Signal mining and analysis of drug-related thrombocytopenia based on FAERS database

Published on Chinese Journal of Pharmacoepidemiology 2025,34(12):1382-1389.
2813 times 569 times

ZHOU Guowei ZHANG Hongyan JIAO Yanyan QUAN Xianghua

Thrombocytopenia Adverse drug events FAERS database Pharmacovigilance Signal mining
Details
Research progress on the pharmacological mechanism of kidney-tonifying formulas in the treatment of postmenopausal osteoporosis

Published on Frontiers in Pharmaceutical Sciences 2026,30(1):150-161.
4626 times 612 times

ZHAO Xuechen SUN Yuting XIE Fan LIU Wenjing WANG Piaopiao LI Wenyan

Postmenopausal osteoporosis Kidney-tonifying formulas Pharmacological mechanism Research progress
Details
Study on the pathogenesis of osteoarthritis and the preventive and therapeutic mechanism of small molecules of traditional Chinese medicine

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1965-1974.
4127 times 578 times

ZHANG Hongwei DANG Wenfei JIN Ziming DOU Xia

Osteoarthritis Pathogenesis Small molecule of traditional Chinese medicine Mechanism Apoptosis Inflammation Oxidative stress Ferroptosis
Details
Prediction and analysis of quality markers of Codonopsis Radix pharmacopoeia varieties based on the research progress of chemical constituents and pharmacological effects

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1942-1953.
4570 times 615 times

ZHANG Kaixian LI Na HU Man

Codonopsis Radix Codonopsis pilosula Nannf. var. modesta (Nannf.) L.T.Shen Codonopsis tangshen Oliv. Variety Chemical composition Pharmacological effects Quality markers Atractylenolide II Codotubulosine A
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Efficacy and safety of celecoxib for preemptive analgesia in patients undergoing orthopedic surgery: a Meta-analysis

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1931-1941.
3304 times 501 times

WANG Xiaojie ZHANG Chunxia BAI Feng DONG Zhiqiang QIN Ruili

Celecoxib Preemptive analgesia Preventive analgesia Orthopedic surgery Visual analogue Scale Meta-analysis
Details
Research progress and hotspots in Sophorae tonkinensis toxicity: a visual analysis based on CiteSpace and VOSviewer

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1921-1930.
3440 times 567 times

LI Jinsha PEI Jingnan LI Qian WEI Cailiu HOU Ling ZHANG Hongping DENG Jiagang

Sophorae tonkinensis Toxicity Bibliometrics Visual analysis CiteSpace VOSviewer Rational drug use Metabonomics
Details
The effect of JAK2 rs10119004 genetic polymorphism and C-reactive protein on voriconazole serum trough concentration in patients with invasive fungal disease

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1914-1920.
2842 times 468 times

CHEN Jing ZENG Ying LU Hong SHI Qunzhi YAN Pan MAO Yanmei

Voriconazole C-reactive protein Inflammation JAK2 gene polymorphism Therapeutic drug monitoring Invasive fungal infection Administration route Individualized administration Pulmonary infection
Details
Application of valsartan in combination with amlodipine in adverse reactions in elderly patients with hypertension

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1906-1913.
3637 times 634 times

ZHOU Yan SU Fei ZHU Junjun LYU Xiongsheng

Valsartan Amlodipine Hypertension Elderly FAERS database Adverse drug event Rational drug use Signal mining
Details
Analysis of adverse reaction signals of denosumab combined with vitamin D based on the FAERS database

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1898-1905.
3480 times 606 times

SHEN Yang CHEN Jihang

Denosumab Vitamin D FAERS database Adverse drug events Osteoporosis Signal mining Off-label use Benign giant cell tumor of bone Myalgia
Details
Research on clinical application data mining of Rhizoma Alismatis and salt-processed Rhizoma Alismatis

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1887-1897.
3697 times 573 times

ZHANG Lu ZHU Cong XU Lifang

Rhizoma Alismatis Salt-processed Rhizoma Alismatis Traditional Chinese medicine processing Clinical application Data mining Damp-heat patterns Spleen-kidney deficiency patterns
Details
Construction and application of the prescription review center in county-level medical community based on the central pharmacy model

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1871-1877.
4332 times 669 times

LIU Lihui WU Jiyong REN Xiudong GAO Tiantian

Prescription review center County-level medical community Central pharmacy Pre-prescription review Homogeneity of pharmaceutical care Rational use
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Comparison of the therapeutic effects of iron sucrose and iron polysaccharide in hemodialysis patients and construction of an infection risk model based on dynamic iron

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1863-1870.
3272 times 487 times

LIU Chengcheng ZHOU Hui JIA Liyue

Renal dialysis Iron sucrose iron Iron polysaccharide Iron metabolism disorders Infectious complications Risk model Chronic kidney disease Risk factors Nomogram
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MCUB as a novel biomarker for prognosis and its molecular characterization in cancer

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1853-1862.
3129 times 512 times

LYU Xiaodan LIU Pingyu

Mitochondrial calcium uniporter dominant negative subunit beta Pan-cancer analysis Prognostic biomarker Immune infiltration Drug sensitivity Protein-protein interaction The cancer genome atlas
Details