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Exploration of the molecular mechanism of Guizhi Tang’s regulation on liver lipid metabolism based on multi-omics analysis

Published on Frontiers in Pharmaceutical Sciences 2026,30(1):30-41.
2948 times 644 times

SONG Haijin SONG Qi DOU Baokai ZHANG Huanhuan HUO Hairu SUI Feng

Guizhi Tang Transcriptomics Lipidomics Lipid metabolism Pungent-warm medicinal property Molecular mechanism Liver Protein-protein interaction
Details
The mechanism of action of Cassiae Semen for constipation based on network pharmacology analysis

Published on Frontiers in Pharmaceutical Sciences 2026,30(1):23-29.
3147 times 576 times

SUN Qiqi MAO Weiru WANG Yuheng YUAN Meng WU Xinyu YAN Hailong WANG Kun

Cassiae Semen Constipation Network pharmacology Molecular docking Molecular dynamics simulation Prostaglandin-endoperoxide synthase 2 Tumor necrosis factor
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Comprehensive analysis of quality markers for Xiaoding ointment based on multi-dimensional feature fusion

Published on Frontiers in Pharmaceutical Sciences 2026,30(1):12-22.
3258 times 680 times

CHANG Dengxi LI Wenxia DAI Haoen ZHANG Yan CHANG Chengdong

Xiaoding ointment Multi-dimensional feature network Quality marker Component analysis Molecular docking Quality control Pharmacological effects
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Exploring the in vitro anti-tumor effect and mechanism of Rumex chalepensis based on network pharmacology

Published on Frontiers in Pharmaceutical Sciences 2026,30(1):2-11.
2797 times 600 times

GUO Changhong YAN Guangjun MIAO Qing LIU Limei XU Jing LIU Chong WANG Yejing XIANG Caiqiong

Rumex chalepensis Network pharmacology Gastric cancer PI3K/Akt signaling pathway Apoptosis Cell cycle arrest Multi-target action Natural anti-tumor drug
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Analysis of disease burden and future trends of chronic hepatitis C among individuals aged ≥50 years in China and globally from 1990 to 2021

Published on Chinese Journal of Pharmacoepidemiology 2026,35(2):164-172.
3379 times 816 times

CHEN Si CHEN Guannan CHEN Qian ZHAO Wei

Chronic hepatitis C Disease burden Incidence Disability-adjusted life years
Details
Efficacy of Tangganjian pills and semaglutide on patients with type 2 diabetes and obesity and its impacts on intestinal mucosal barrier function and serum kisspeptin

Published on Chinese Journal of Pharmacoepidemiology 2026,35(2):133-139.
3420 times 799 times

HU Lijuan ZHU Hao WAN Jing

Tangganjian pill Semaglutide Type 2 diabetes Obesity Intestinal mucosal barrier function Kisspeptin
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A case report of rhabdomyolysis, liver and kidney dysfunction induced by capecitabine tablets

Published on Chinese Journal of Pharmacoepidemiology 2026,35(2):237-240.
3583 times 796 times

YANG Saicheng XIA Xiuyuan

Capecitabine Rhabdomyolysis Liver dysfunction Kidney dysfunction Adverse drug reactions
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Adverse drug event signal mining of ezetimibe monotherapy and compound preparations based on the FAERS database

Published on Chinese Journal of Pharmacoepidemiology 2026,35(2):156-163.
4013 times 906 times

HUANG Yan YU Yang

Ezetimibe Single tablet compound preparation containing ezetimibe Combination therapy Adverse drug event Signal mining Pharmacovigilance
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Rhabdomyolysis induced by concomitant voriconazole and trimethoprim-sulfamethoxazole in a patient with pulmonary fungal infection: a case report

Published on Chinese Journal of Pharmacoepidemiology 2026,35(2):221-226.
3186 times 723 times

ZHANG Jiajun WANG Zhen ZHOU Ying ZHANG Peng GONG Xuepeng

Voriconazole Trimethoprim-sulfamethoxazole Rhabdomyolysis Adverse drug reaction
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A survey of the current status of tetanus passive immunization agent application in children's hospitals

Published on Chinese Journal of Pharmacoepidemiology 2026,35(2):147-155.
4941 times 854 times

LIN Jinxiang CHEN Yushuang KE Huichao WANG Jing ZHANG Qingchi

Tetanus Children Tetanus antitoxin Human tetanus immunoglobulin Immunoprophylaxis Potentially unnecessary use
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Application of transformative learning theory in hysteroscopy teaching and training to trainee physicians

Published on Journal of Mathematical Medicine 2026,39(1):75-80.
2914 times 709 times

WANG Jing SONG Dongmei ZHOU Qiaoyun XIA Enlan HUO Jing ZHANG Xin JIN Shengyang ]HUANG Xiaowu

Transformative learning theory Trainee physicians Hysteroscopy Teaching Critical reflection
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Challenges and system construction of reproductive medicine ethics education

Published on Journal of Mathematical Medicine 2026,39(1):68-74.
3382 times 790 times

FAN Qigang KANG Jiawei ZHANG Yuanzhen WANG Mei

Reproductive medicine Medical ethics Ethical education Artificial intelligence Clinical practice
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Analysis of the evidence mapping of clinical studies on the treatment of osteoporosis with Chinese patent medicines

Published on Journal of Mathematical Medicine 2026,39(1):58-67.
4668 times 840 times

CHEN Tianxin ZHU Yuqi ZHANG Shuai YANG Shengping

Osteoporosis Chinese patent medicines Clinical studies Systematic review Meta-analysis Evidence mapping
Details
Exploring the potential pathway of puerarin in the treatment of oral submucous fibrosis based on bioinformatics methods and cell experiments

Published on Journal of Mathematical Medicine 2026,39(1):45-57.
3450 times 837 times

LU Ruqing GUO Sheng PENG Jiamei LI Yijie LIU Gen

Puerarin Oral submucous fibrosis Bioinformatics Network pharmacology Molecular docking Molecular dynamics simulation Cell experiments
Details
Visual analysis of research hotspots and trends in the association between senile sarcopenia and mitochondria based on Web of Science database

Published on Journal of Mathematical Medicine 2026,39(1):34-44.
5081 times 749 times

YU Ruoru FENG Cheng ZHENG Shuyu WU Lei YONG Rulin

Senile sarcopenia Mitochondria Web of Science Bibliometrics Visual analysis
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Epidemiological characteristics, influencing factors, and prevention and control effects of hand, foot and mouth disease in Enshi prefecture from 2010 to 2020

Published on Journal of Mathematical Medicine 2026,39(1):24-33.
3197 times 729 times

SU Yanwen WU Yun SUN Qiu GUO Caihong WANG Lianwen

Hand foot and mouth disease Bayesian spatiotemporal model SARIMA model Spatiotemporal characteristics Influencing factors
Details
Analysis and prediction of the changing trend of the disease burden of tension-type headache in China from 1990 to 2021

Published on Journal of Mathematical Medicine 2026,39(1):12-23.
3905 times 831 times

XU Xinyu LIU Yuquan REN Peihua ZHANG Yuxuan YUN Zixuan YUAN Yanning SHI Wenyan LUO Qiaoshan ZHANG Kun XING Juanli

Tension-type headache Disease burden Incidence Prevalence Disability-adjusted life year Joinpoint regression analysis Bayesian age-period-cohort model
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Search strategies for systematic review and Meta-analysis: from PICO to large language models

Published on Journal of Mathematical Medicine 2026,39(1):2-11.
3812 times 837 times

HUANG Sidie CUI Nuan ZHANG Wen ZENG Yidi LI Lin LI Jinxia LIANG Hao

Systematic review Meta-analysis Retrieval strategy PICO Large language models
Details
Message from the editors-in-chief

Published on Chinese Journal of Pharmacoepidemiology 2026,35(1):1.
2737 times 661 times

ZHAN Siyan XIN Huawen ZHAI Suodi

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Immune-related hyperglycemia accompanied by optic neuritis in extensive-stage small cell lung cancer: a case report and pharmaceutical management

Published on Chinese Journal of Pharmacoepidemiology 2026,35(1):114-120.
3187 times 722 times

ZHENG Xinyi XU Xin WANG Xiaohang SU Yingjie

Extensive-stage small cell lung cancer Serplulimab Immune-related hyperglycemia Immune-related optic neuritis Immune-related adverse events
Details