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Signals mining and analysis of deucravacitinib adverse drug events based on FAERS database

Published on Chinese Journal of Pharmacoepidemiology 2025,34(4):419-427.
9445 times 2874 times

HU Ye GONG Qineng ZHANG Linlin WANG Aming QI Wang MIAO Yang

Deucravacitinib Adverse drug events FAERS database Psoriasis Signal mining Pharmacovigilance
Details
Clinical characteristics of liver injury induced by different types of drugs and Logistic analysis of the influencing factors on the prognosis

Published on Chinese Journal of Pharmacoepidemiology 2025,34(4):410-418.
9830 times 3239 times

ZHANG Yafei CAO Yi WANG Zhihao WANG Yuanyuan

Drug-induced liver injury Clinical characteristics Medication history Prognosis analysis Influencing factors
Details
Exploration on medication pattern of traditional Chinese medicine treatment for non-small cell lung cancer based on real world data

Published on Chinese Journal of Pharmacoepidemiology 2025,34(4):398-409.
12210 times 2949 times

LI Junya SHI Yanglin YANG Jianya LI Ya LI Suyun

Non-small cell lung cancer Traditional Chinese medicine Real-word data Latent structure model Association rule Medication pattern
Details
Study on the prevention of sufentanil-induced cough reflex during general anesthesia induction of breast mass resection by auricular point bean embedding

Published on Chinese Journal of Pharmacoepidemiology 2025,34(4):391-397.
9124 times 1910 times

LUO Rui LI Yao WU Yongli WANG Weiwei

Auricular point bean embedding Sufentanil Breast mass resection Coughing response Prevention Generalized eneralized estimation equation
Details
Effect of dexmedetomidine on the median effective concentration of ropivacaine during sciatic nerve block combined with femoral nerve block in patients undergoing lower extremity surgery

Published on Chinese Journal of Pharmacoepidemiology 2025,34(4):380-390.
8552 times 1866 times

CHEN Zuquan GU Xiaoping ZOU Wenjun HE Fuqiang

Dexmedetomidine Ropivacaine Sciatic nerve block Femoral nerve block Median effective concentration
Details
Effect of flurbiprofen axetil on postoperative catheter-related bladder discomfort: a randomized, controlled, double-blind trial

Published on Chinese Journal of Pharmacoepidemiology 2025,34(4):373-379.
10257 times 2772 times

LIU Zhidan SONG Bo LI Liping GUO Yinhao HE Hongxia XU Suihan ZHANG Yonghong LI Jun

Flurbiprofen axetil Transurethral resection of the prostate Catheter-related bladder discomfort Randomized controlled trial
Details
Guide on Methodological Standards in Pharmacoepidemiology in China (2nd edition) and their series interpretation (4): sources of research question and study protocol development in pharmacoepidemiological research

Published on Chinese Journal of Pharmacoepidemiology 2025,34(4):365-372.
8911 times 2717 times

CHENG Yinchu HE Na YAN Yingying ZHAN Siyan SUN Feng

Pharmacoepidemiology Methodology Guidelines Research question Study protocol
Details
Constructing a predictive model for mild cognitive impairment in elderly individuals with coexisting multiple diseases based on machine learning algorithms

Published on New Medicine 2025,35(4):409-418.
6131 times 1308 times

ZHANG Lei HU Xintao CHEN Wei XIANG Xuan ZOU Ting MIAO Haijun WU Ruikai ZHOU Xiaohui

Mild cognitive impairment Coexistence of multiple illnesses Machine learning Predictive model Shapley addition explantation algorithm
Details
Predictive value of preoperative clinical parameters for early recurrence after radical resection of colorectal cancer liver metastases

Published on New Medicine 2025,35(4):419-429.
5028 times 1035 times

MA Ruidong LI Jiawei LUO Shiqiao

Colorectal cancer liver metastases Early recurrence Radical resection Prediction model Nomogram
Details
Application of innovative nanoprobes for targeted inhibition of clear cell renal cell carcinoma via MN receptors

Published on New Medicine 2025,35(4):386-393.
4518 times 1064 times

ZHU Hanwen YAN Yishuo QI Xin LI Cong WANG Ziqi

Clear cell renal cell carcinoma Tumor imaging Nanomaterials Targeted inhibition MN receptor
Details
Causal association between ceramide and salt sensitive hypertension based on plasma metabolomics

Published on New Medicine 2025,35(4):367-375.
4627 times 1059 times

YANG Xiaojun ZHANG Bowen LI Boya WEN Fuyuan QU Aibin YAO Xinyue ZHANG Ling

Plasma metabolites Salt sensitive hypertension Metabolomics Mendelian randomization
Details
Development and future prospect of project-based learning in medical education from interdisciplinary perspective: taking the teaching practice of Sichuan University as an example

Published on New Medicine 2025,35(4):483-490.
5307 times 1266 times

WEI Chuzhong DENG Linghui ZHOU Xianghong ZOU Xiaoli YUE Jirong ZHAN Yu QIU Yang CHEN Sujun LYU Xiaojun YANG Lu QIU Shi

Interdisciplinary integration Project-based learning Medical education Education reform Intelligent teaching platform
Details
Research progress on mechanisms of endocrine therapy resistance in prostate cancer

Published on New Medicine 2025,35(4):452-460.
5959 times 1162 times

QI Zihao WANG Leijie WU Linjie BAI Xiaojie FAN Jiuming WANG Tiankun HAN Yutong YU Ying GUO Zhongqiang ZENG Xiantao

Prostate cancer Androgen receptor Androgen deprivation therapy Castration resistance Drug resistance mechanism
Details
Adamantinoma of long bones combined with giant cell tumor of bone: a case report and literature review

Published on New Medicine 2025,35(4):476-482.
4201 times 1057 times

ZHU Yali FAN Meng WU Juan YANG Guifang

Adamantinoma of long bones Giant cell tumor of bone Pathologic diagnosis Bone tumors
Details
Effect of T lymphocyte on hepatic stellate cell activation in liver fibrosis

Published on New Medicine 2025,35(4):469-475.
4676 times 974 times

GONG Xiaoqian WEI Yehuang WANG Rongrong LIU Xudong

T lymphocyte Liver fibrosis Hepatic stellate cells Immune microenvironment
Details
Efficacy and safety of Tislelizumab combined with chemotherapy in the treatment of non-small cell lung cancer: a Meta-analysis

Published on New Medicine 2025,35(4):442-451.
4812 times 1116 times

WANG Kuan TAN Xiao GUO Yanni

Non-small cell lung cancer Tislelizumab Chemotherapy Effectiveness Safety Meta-analysis
Details
The regulatory mechanism of deferoxamine spray in promoting the healing of chronic wounds in third-degree burns

Published on New Medicine 2025,35(4):394-401.
5351 times 1075 times

CHAI Langjie LI Qin GUO Liang HUANG Jianglong

Deferoxamine Third-degree burns Chronic wound healing Ferroptosis
Details
Early identification and treatment of macrolide-resistant severe Mycoplasmal pneumoniae pneumonia in children

Published on New Medicine 2025,35(4):461-468.
4997 times 1289 times

YU Man YE Leping

Mycoplasma pneumoniae Macrolide antibiotics Drug resistance Severe pneumonia Early identification Treatment
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The effect of subhealth on aggressive behavior among middle school students in a district of Chongqing

Published on New Medicine 2025,35(4):402-408.
4270 times 986 times

YE Siyan WANG Lin XI Xuan LIU Qin

Aggressive behavior Physical-mental subhealth Physical subhealth Mental subhealth Middle school students
Details
Analysis of influencing factors on hospitalization time for mild ischemic colitis

Published on New Medicine 2025,35(4):436-441.
4893 times 927 times

FANG Lisha LI Huan LONG Hui WU Qingming

Ischemic colitis Hospitalization duration Influencing factors
Details