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The effect of JAK2 rs10119004 genetic polymorphism and C-reactive protein on voriconazole serum trough concentration in patients with invasive fungal disease

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1914-1920.
6170 times 1096 times

CHEN Jing ZENG Ying LU Hong SHI Qunzhi YAN Pan MAO Yanmei

Voriconazole C-reactive protein Inflammation JAK2 gene polymorphism Therapeutic drug monitoring Invasive fungal infection Administration route Individualized administration Pulmonary infection
Details
Application of valsartan in combination with amlodipine in adverse reactions in elderly patients with hypertension

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1906-1913.
7955 times 1375 times

ZHOU Yan SU Fei ZHU Junjun LYU Xiongsheng

Valsartan Amlodipine Hypertension Elderly FAERS database Adverse drug event Rational drug use Signal mining
Details
Analysis of adverse reaction signals of denosumab combined with vitamin D based on the FAERS database

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1898-1905.
7152 times 1297 times

SHEN Yang CHEN Jihang

Denosumab Vitamin D FAERS database Adverse drug events Osteoporosis Signal mining Off-label use Benign giant cell tumor of bone Myalgia
Details
Research on clinical application data mining of Rhizoma Alismatis and salt-processed Rhizoma Alismatis

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1887-1897.
8256 times 1345 times

ZHANG Lu ZHU Cong XU Lifang

Rhizoma Alismatis Salt-processed Rhizoma Alismatis Traditional Chinese medicine processing Clinical application Data mining Damp-heat patterns Spleen-kidney deficiency patterns
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Construction and application of the prescription review center in county-level medical community based on the central pharmacy model

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1871-1877.
9999 times 1641 times

LIU Lihui WU Jiyong REN Xiudong GAO Tiantian

Prescription review center County-level medical community Central pharmacy Pre-prescription review Homogeneity of pharmaceutical care Rational use
Details
Comparison of the therapeutic effects of iron sucrose and iron polysaccharide in hemodialysis patients and construction of an infection risk model based on dynamic iron

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1863-1870.
7074 times 1147 times

LIU Chengcheng ZHOU Hui JIA Liyue

Renal dialysis Iron sucrose iron Iron polysaccharide Iron metabolism disorders Infectious complications Risk model Chronic kidney disease Risk factors Nomogram
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MCUB as a novel biomarker for prognosis and its molecular characterization in cancer

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1853-1862.
6438 times 1088 times

LYU Xiaodan LIU Pingyu

Mitochondrial calcium uniporter dominant negative subunit beta Pan-cancer analysis Prognostic biomarker Immune infiltration Drug sensitivity Protein-protein interaction The cancer genome atlas
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Optimization of ginger charcoal processing technology by analytic hierarchy process-entropy weight method combined with Box-Behnken response surface methodology

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1838-1845.
6966 times 1242 times

QIAN Yuhang YE Xide FENG Xiaolong BU Junwen WU Yu ZHONG Lingyun PENG Lingzhen

Dry ginger Charred ginger Analytic hierarchy process Entropy weight method Box-Behnken response surface methodology 6-Gingerol 8-Gingerol 10-Gingerol Gingerone
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Optimization of the decoction process for Epimedium koreanum Nakai. boiled powder based on analytic hierarchy process-entropy weighting method combined with Box-Behnken design-response surface method

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1830-1837.
7145 times 1282 times

FAN Hua ZHANG Wei DONG Yufeng ZHANG Xiuyun XUE Jiannan QI Bin LIU Li

Epimedium koreanum Nakai. Boiled powder Crushing particle size Boiling process Analytic hierarchy process-entropy weight method Box-Behnken response surface methodology High-performance liquidchromatography Ultravioletvisible spectrophotometry
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The action mechanism of Shaoyao decoction in the treatment of knee osteoarthritis based on network pharmacology and Mendelian randomization

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1821-1829.
7592 times 1237 times

SONG Yang XU Fei LIU Hansen ZHANG Houjian

Shaoyao decoction Knee osteoarthritis Network pharmacology Mendelian randomization Protein-protein interaction Genome-wide association studies Single nucleotide polymorphisms Signaling pathway
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Exploring the potential mechanism of Codonopsis pilosula in treating myocardial injury based on network pharmacology and molecular docking

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1811-1820.
7915 times 1337 times

ZHENG Huanqin SHI Xiaodong SHI Wenyin CHENG Shuai

Codonopsis pilosula Myocardial injury Network pharmacology Molecular docking Protein-protein interaction Signaling pathways Inflammation Apoptosis Metabolic homeostasis
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Exploring the anti-uterine fibroids mechanism of Rubia yunnanensis based on network pharmacology and molecular docking technology

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1801-1810.
7226 times 1291 times

WANG Hong LI Yanhua

Rubia yunnanensis Uterine fibroids Network pharmacology Molecular docking type Action mechanism Target Protein-protein interaction Signaling pathways
Details
Two-dimensional analysis and collaborative governance of the “mentor-student contradiction” in medical postgraduate education: an empirical study based on the structure-process model

Published on Journal of Mathematical Medicine 2025,38(11):873-882.
7884 times 1254 times

LIU Yanquan SHEN Jianzhen NI Jindong HE Honghua ZHONG Zhihong CHEN Xiaojun HUANG Jinlong WANG Yili HONG Xiaomei LIAO Linying ZHANG Jingdong

Medical postgraduate students Mentor-student contradiction Structure-process model Two-dimensional analysis Collaborative governance Empirical research
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Exfoliative esophagitis associated with the effects of multiple medications: a case report

Published on Journal of Mathematical Medicine 2025,38(11):868-872.
6450 times 1208 times

CHEN Kun LYU Fei DING Xiangwu

Polypharmacy Exfoliative esophagitis Gastrointestinal tract Complication Medication management
Details
Research progress on the neuromodulation mechanisms of acupuncture and moxibustion analgesia based on functional magnetic resonance imaging

Published on Journal of Mathematical Medicine 2025,38(11):860-867.
8358 times 1420 times

ZHONG Huagui TIAN Lu XIE Hongwu LIN Shangxun LIAN Tiansheng

Functional magnetic resonance imaging Neuromodulation Acupuncture Moxibustion
Details
The incidence of behavioral and psychological symptoms of dementia and various symptom types among dementia patients in China: a Meta-analysis

Published on Journal of Mathematical Medicine 2025,38(11):846-859.
8672 times 1467 times

DING Ling YAO Qian SUN Hongqiong JIANG Shengfeng

Dementia Behavioral and psychiatric symptoms Incidence China Meta-analysis
Details
Analysis of learning curve and clinical efficacy of percutaneous vertebroplasty for osteoporotic vertebral compression fracture

Published on Journal of Mathematical Medicine 2025,38(11):839-845.
6576 times 1196 times

ZHAN Dongdong ZHANG Xiaoran ZHANG Lutong LI Jing

Osteoporotic vertebral compression fracture Percutaneous vertebroplasty Cumulative summation method Learning curve Clinical efficacy
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The mechanism of Fuzhisan in the treatment of Alzheimer's disease based on network pharmacology and molecular docking technology

Published on Journal of Mathematical Medicine 2025,38(11):825-838.
7391 times 1465 times

CHEN Fuping TIAN Ruoshi YANG Yan HE Xirui

Alzheimer's disease Fuzhisan Network pharmacology Molecular docking Mechanism
Details
Analysis of knowledge graphs related to cardiovascular and cerebrovascular diseases such as coronary heart disease and stroke based on Web of Science database

Published on Journal of Mathematical Medicine 2025,38(11):811-824.
7276 times 1399 times

LI Jiayu ZHOU Shuang ZHAO Yijia CAI Wenjun ZHOU Ying

Coronary heart disease Stroke Cardiovascular and cerebrovascular diseases Web of Science Knowledge graph Bibliometrics Visual analysis
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Analysis and prediction of disease burden of ischemic stroke in China and globally from 1990 to 2021

Published on Journal of Mathematical Medicine 2025,38(11):800-810.
11553 times 1754 times

ZHU Yanping HE Wangsheng YANG Wenming LI Mengmeng LONG Shizhen

Ischemic stroke Disease burden Incidence Mortality Disability-adjusted life years
Details