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Study on the antianxiety effect of xanthohumol by inhibiting FKBP51 in the brain

Published on Frontiers in Pharmaceutical Sciences 2026,30(1):42-51.
3832 times 1012 times

SHAO Qi ZHANG Jing MA Shanbo ZHANG Kun CHONG Ye

Xanthohumol FKBP51 Anxiety disorder Brain-derived neurotrophic factor Adeno-associated virus Molecular docking Open field test Elevated plus-maze
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Exploration of the molecular mechanism of Guizhi Tang’s regulation on liver lipid metabolism based on multi-omics analysis

Published on Frontiers in Pharmaceutical Sciences 2026,30(1):30-41.
4772 times 1151 times

SONG Haijin SONG Qi DOU Baokai ZHANG Huanhuan HUO Hairu SUI Feng

Guizhi Tang Transcriptomics Lipidomics Lipid metabolism Pungent-warm medicinal property Molecular mechanism Liver Protein-protein interaction
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The mechanism of action of Cassiae Semen for constipation based on network pharmacology analysis

Published on Frontiers in Pharmaceutical Sciences 2026,30(1):23-29.
4977 times 1236 times

SUN Qiqi MAO Weiru WANG Yuheng YUAN Meng WU Xinyu YAN Hailong WANG Kun

Cassiae Semen Constipation Network pharmacology Molecular docking Molecular dynamics simulation Prostaglandin-endoperoxide synthase 2 Tumor necrosis factor
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Comprehensive analysis of quality markers for Xiaoding ointment based on multi-dimensional feature fusion

Published on Frontiers in Pharmaceutical Sciences 2026,30(1):12-22.
5170 times 1236 times

CHANG Dengxi LI Wenxia DAI Haoen ZHANG Yan CHANG Chengdong

Xiaoding ointment Multi-dimensional feature network Quality marker Component analysis Molecular docking Quality control Pharmacological effects
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Exploring the in vitro anti-tumor effect and mechanism of Rumex chalepensis based on network pharmacology

Published on Frontiers in Pharmaceutical Sciences 2026,30(1):2-11.
4406 times 1141 times

GUO Changhong YAN Guangjun MIAO Qing LIU Limei XU Jing LIU Chong WANG Yejing XIANG Caiqiong

Rumex chalepensis Network pharmacology Gastric cancer PI3K/Akt signaling pathway Apoptosis Cell cycle arrest Multi-target action Natural anti-tumor drug
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Analysis of disease burden and future trends of chronic hepatitis C among individuals aged ≥50 years in China and globally from 1990 to 2021

Published on Chinese Journal of Pharmacoepidemiology 2026,35(2):164-172.
5700 times 1453 times

CHEN Si CHEN Guannan CHEN Qian ZHAO Wei

Chronic hepatitis C Disease burden Incidence Disability-adjusted life years
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Efficacy of Tangganjian pills and semaglutide on patients with type 2 diabetes and obesity and its impacts on intestinal mucosal barrier function and serum kisspeptin

Published on Chinese Journal of Pharmacoepidemiology 2026,35(2):133-139.
5700 times 1456 times

HU Lijuan ZHU Hao WAN Jing

Tangganjian pill Semaglutide Type 2 diabetes Obesity Intestinal mucosal barrier function Kisspeptin
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A case report of rhabdomyolysis, liver and kidney dysfunction induced by capecitabine tablets

Published on Chinese Journal of Pharmacoepidemiology 2026,35(2):237-240.
6161 times 1446 times

YANG Saicheng XIA Xiuyuan

Capecitabine Rhabdomyolysis Liver dysfunction Kidney dysfunction Adverse drug reactions
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Adverse drug event signal mining of ezetimibe monotherapy and compound preparations based on the FAERS database

Published on Chinese Journal of Pharmacoepidemiology 2026,35(2):156-163.
7131 times 1720 times

HUANG Yan YU Yang

Ezetimibe Single tablet compound preparation containing ezetimibe Combination therapy Adverse drug event Signal mining Pharmacovigilance
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Rhabdomyolysis induced by concomitant voriconazole and trimethoprim-sulfamethoxazole in a patient with pulmonary fungal infection: a case report

Published on Chinese Journal of Pharmacoepidemiology 2026,35(2):221-226.
5679 times 1410 times

ZHANG Jiajun WANG Zhen ZHOU Ying ZHANG Peng GONG Xuepeng

Voriconazole Trimethoprim-sulfamethoxazole Rhabdomyolysis Adverse drug reaction
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A survey of the current status of tetanus passive immunization agent application in children's hospitals

Published on Chinese Journal of Pharmacoepidemiology 2026,35(2):147-155.
8493 times 1590 times

LIN Jinxiang CHEN Yushuang KE Huichao WANG Jing ZHANG Qingchi

Tetanus Children Tetanus antitoxin Human tetanus immunoglobulin Immunoprophylaxis Potentially unnecessary use
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Application of transformative learning theory in hysteroscopy teaching and training to trainee physicians

Published on Journal of Mathematical Medicine 2026,39(1):75-80.
4071 times 1061 times

WANG Jing SONG Dongmei ZHOU Qiaoyun XIA Enlan HUO Jing ZHANG Xin JIN Shengyang ]HUANG Xiaowu

Transformative learning theory Trainee physicians Hysteroscopy Teaching Critical reflection
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Challenges and system construction of reproductive medicine ethics education

Published on Journal of Mathematical Medicine 2026,39(1):68-74.
4932 times 1176 times

FAN Qigang KANG Jiawei ZHANG Yuanzhen WANG Mei

Reproductive medicine Medical ethics Ethical education Artificial intelligence Clinical practice
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Analysis of the evidence mapping of clinical studies on the treatment of osteoporosis with Chinese patent medicines

Published on Journal of Mathematical Medicine 2026,39(1):58-67.
7127 times 1261 times

CHEN Tianxin ZHU Yuqi ZHANG Shuai YANG Shengping

Osteoporosis Chinese patent medicines Clinical studies Systematic review Meta-analysis Evidence mapping
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Exploring the potential pathway of puerarin in the treatment of oral submucous fibrosis based on bioinformatics methods and cell experiments

Published on Journal of Mathematical Medicine 2026,39(1):45-57.
4976 times 1246 times

LU Ruqing GUO Sheng PENG Jiamei LI Yijie LIU Gen

Puerarin Oral submucous fibrosis Bioinformatics Network pharmacology Molecular docking Molecular dynamics simulation Cell experiments
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Visual analysis of research hotspots and trends in the association between senile sarcopenia and mitochondria based on Web of Science database

Published on Journal of Mathematical Medicine 2026,39(1):34-44.
6639 times 1145 times

YU Ruoru FENG Cheng ZHENG Shuyu WU Lei YONG Rulin

Senile sarcopenia Mitochondria Web of Science Bibliometrics Visual analysis
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Epidemiological characteristics, influencing factors, and prevention and control effects of hand, foot and mouth disease in Enshi prefecture from 2010 to 2020

Published on Journal of Mathematical Medicine 2026,39(1):24-33.
4522 times 1094 times

SU Yanwen WU Yun SUN Qiu GUO Caihong WANG Lianwen

Hand foot and mouth disease Bayesian spatiotemporal model SARIMA model Spatiotemporal characteristics Influencing factors
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Analysis and prediction of the changing trend of the disease burden of tension-type headache in China from 1990 to 2021

Published on Journal of Mathematical Medicine 2026,39(1):12-23.
5627 times 1249 times

XU Xinyu LIU Yuquan REN Peihua ZHANG Yuxuan YUN Zixuan YUAN Yanning SHI Wenyan LUO Qiaoshan ZHANG Kun XING Juanli

Tension-type headache Disease burden Incidence Prevalence Disability-adjusted life year Joinpoint regression analysis Bayesian age-period-cohort model
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Search strategies for systematic review and Meta-analysis: from PICO to large language models

Published on Journal of Mathematical Medicine 2026,39(1):2-11.
6260 times 1574 times

HUANG Sidie CUI Nuan ZHANG Wen ZENG Yidi LI Lin LI Jinxia LIANG Hao

Systematic review Meta-analysis Retrieval strategy PICO Large language models
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Message from the editors-in-chief

Published on Chinese Journal of Pharmacoepidemiology 2026,35(1):1.
4035 times 1108 times

ZHAN Siyan XIN Huawen ZHAI Suodi

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