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Advances in pharmacists’ prescription management: intervention and analysis in antimicrobial use

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):887-893.
6230 times 990 times

WANG Weijuan GU Lijia ZHU Yanyan GAO Hongrui

Pharmacist intervention Antimicrobial management Prescription review Intelligent alert system Rational drug use
Details
Research progress of antibody-drug conjugates and analysis of their current application status in gastric cancer patients

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):877-886.
6071 times 908 times

ZHU Wenbing GUO Chao DAI Yujie QIN Yue ZHOU Jiangping ZHU Wenjing

Antibody-drug conjugates Targeted therapy Gastric cancer patients Research progress Application Status
Details
Research progress on decolorization methods of saponins

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):868-876.
8915 times 1093 times

LIAO Binbin ZHANG Jianying ZHANG Xinjian WANG Hongyun CAI Qunhu ZUO Aixue

Saponins Extraction Decolorization method Oxidative decolorization Reduction decolorization Adsorption decolorization Process decolorization Research progress
Details
Research of progress medicinal components and quality control of Sambucus L. plants

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):859-867.
7065 times 1092 times

YANG Liu ZHAO Chenxi CHEN Anxin WANG Dongna WANG Meihua LI Tingting

Sambucus L. Application Chemical constituents Pharmacological effects Quality standard
Details
Research progress on the structural modification and anti-lung cancer activity of natural product erianin

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):849-858.
6911 times 901 times

LIU Jing ZHANG Na LI Xiaolu ZHAO Bin

Erianin Structural modification Anti-lung cancer Molecular mechanisms Research progress
Details
Research progress on the hepatoprotective mechanism of Berberis and its active components

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):832-848.
6582 times 1066 times

YANG Guibin GUI Mingan GUO Hao ZHUOMA Dongzhi YUAN Ruiying

Berberis Active ingredient Liver disease Hepatoprotective effect
Details
Research progress on toxicological evaluation and pharmacological effects of Sweet potato (Ipomaea batatas L.) leaves

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):816-831.
8794 times 1070 times

LYU Haihua HUANG Chenchen TANG Qiuyan LIANG Sen QIN Linfeng FENG Junzhou GAO Xingxin

Sweet potato leaves Toxicological evaluation Pharmacological effects Research progress Development and utilization
Details
Exploration of the pharmacological activities and medicinal values of different parts of Sea buckthorn

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):802-815.
9225 times 1257 times

LIU Qiuyue ZHANG Zhendong LIU Shumin LU Fang

Sea buckthorn fruit Sea buckthorn leaves Sea buckthorn seeds Pharmacological effects Development and utilization
Details
Placebo effect in children with acute upper respiratory infection: a systematic review and Meta-analysis

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):794-801.
6488 times 951 times

YANG Jinyu NIU Liqing CAI Qiuhan XU Yaqian CHEN Lulu HU Siyuan

Children Upper respiratory infection Placebo effect Systematic review Meta-analysis
Details
Analysis of influencing factors and construction of risk prediction model for adverse bleeding reactions in patients with acute cerebral infarction treated with alteplase

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):787-793.
6043 times 915 times

LIN Qiao YANG Jingying ZHOU Yayan ZHOU Weibin MA Xiaotong

Acute cerebral infarction Alteplase Thrombolysis Bleeding Risk factors Risk prediction model
Details
Comparison of the efficacy of different fluid resuscitation regimens on traumatic hemorrhagic shock

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):779-786.
6402 times 926 times

HE Mengxi PAN Aidi CHEN Linglong YE Ru

Fluid resuscitation Therapeutic hypothermia Traumatic hemorrhagic shock
Details
The clinical efficacy of piperacillin-tazobactam sodium combined with budesonide in the treatment of patients with AECOPD

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):772-778.
6506 times 897 times

WANG Xiaofang WU Yueming PAN Liuhua

Piperacillin-tazobactam sodium Budesonide Acute exacerbation of chronic obstructive pulmonary disease Inflammatory factors
Details
Effect of GnRH antagonist combined with rLH on IVF outcomes in patients with low LH levels

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):764-771.
6017 times 877 times

CHEN Mei YANG Lihua WANG Rong

Gonadotropin-releasing hormone antagonist Recombinant luteinizing hormone Low luteinizing hormone Ovarian responsiveness In vitro fertilization pregnancy
Details
Feasibility study on mercury-free green testing of hydrochloride salt drugs in the Chinese Pharmacopoeia

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):756-763.
6191 times 961 times

LIU Huiying LI Shangying HUANG Hai XU Wankui

Hydrochloride drugs Method substitution Mercury salt elimination Green drug testing Quality control
Details
Optimization of the matrix formulation of Shangjin Zhitong gel patch by Box-Behnken response surface methodology

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):747-755.
6686 times 912 times

LONG Zechun LIU Yang SHI Qiongzhi LIU Hui XIONG Chengjie HU Hua

Shangjin Zhitong gel Gel patch Formulation optimization Box-Behnken response surface methodology
Details
Protection mechanism of myocardial tissues of Wnt/β-catenin signaling inhibition by GAS5 in rats with coronary artery disease

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):739-746.
6855 times 891 times

WANG Qunye LI Chunhong XU Lu

Growth arrest-specific 5 Wnt/β-catenin signaling pathway Coronary heart disease Myocardial injury Myocardial enzymes Apoptosis
Details
Mechanism of Xianju Xiaozhen decoction in treating atopic dermatitis based on network pharmacology and molecular docking

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):730-738.
5973 times 931 times

CHEN Wendong ZHOU Chao XU Xinchang FENG Shuhang GUAN Jiaqi WANG Lei ZHA Weifeng

Xianju Xiaozhen decoction Atopic dermatitis Molecular mechanism Network pharmacology Molecular docking
Details
The effect of butylphthalein regulating the PI3K/Akt/CREB signaling pathway on cisplatin-induced inflammation and apoptosis in PC12 cells

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):721-729.
5819 times 945 times

YAO Mengyuan WEN Min HUANG Zhengyuan CHEN Peng ZHOU Benhong

Butylphthalide Neuroprotection Apoptosis Chemotherapy-related cognitive impairment PC12 cells
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Analysis of a case of 5-hydroxytryptamine syndrome caused by oxycodone hydrochloride sustained-release tablets

Published on Chinese Journal of Pharmacoepidemiology 2025,34(6):715-719.
10423 times 3123 times

ZHANG Mengyu XING Xiaomin WANG Jikai LI Jinfeng ZHANG Yuan JING Fanbo

Oxycodone hydrochloride sustained-release tablets 5-Hydroxytryptamine Syndrome Morphine sulfate sustained-release tablets Adverse drug reaction
Details
Subcutaneous hematoma complicated with rhabdomyolysis caused by sudden overdose of warfarin: a case report

Published on Chinese Journal of Pharmacoepidemiology 2025,34(6):720-724.
9511 times 3115 times

ZHAO Yinping ZHAO Xiuping QIN Xialing HE Haihua DAI Tao

Warfarin Subcutaneous hematoma Rhabdomyolysis Medication errors
Details