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Research progress on the chemical constituents and pharmacological effects of Chinese yam

Published on Frontiers in Pharmaceutical Sciences 2025,29(12):2098-2111.
8808 times 1443 times

ZHENG Xiaonan SUN Cuige DI Qing HU Liping ZHAO Xiangxuan

Chinese yam Chemical composition Pharmacological effects Chronic atrophic gastritis Drug target Network pharmacology Targeted drugs Natural products
Details
Research on quality management, responsibilities and regulatory measures of the domestic responsible person for drugs

Published on Frontiers in Pharmaceutical Sciences 2025,29(12):2088-2097.
4840 times 919 times

WANG Ying WANG Guangping

Imported drugs Domestic responsible entity Overseas marketing authorization holders Quality management responsibility Responsible entity Obligation Challenge Supervision
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Artificial intelligence reshapes hospital pharmacy practice: advances in application and real-world challenges

Published on Frontiers in Pharmaceutical Sciences 2025,29(12):2080-2087.
8042 times 1374 times

FANG Haiyan HE Qing

Artificial intelligence Hospital pharmacy Machine learning Natural language processing Deep learning Big data Rational use of drug Drug administration
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Thoughts on future smart shared traditional Chinese medicine pharmacy based on the construction practice of regional shared traditional Chinese medicine pharmacy in Hangzhou

Published on Frontiers in Pharmaceutical Sciences 2025,29(12):2072-2079.
4493 times 924 times

YANG Fanlin LIU Guoxiu SUN Qianqian LI Chunjin CHEN Hongmei GUO Junping ZHAI Huaqiang

Regional shared traditional Chinese medicine pharmacy Hangzhou Construction practice Smart shared traditional Chinese medicine pharmacy Traditional Chinese medicine service Questionnaire survey Pharmaceutical administration
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Analysis of the impact of international research on dose rounding of anti-tumor drugs on the cost of anti-tumor drugs in China

Published on Frontiers in Pharmaceutical Sciences 2025,29(12):2065-2071.
3848 times 913 times

REN Lingzhi YU Wenhao WANG Ting TANG Min ZHOU Ziyuan TANG Haochun MENG Jun

Anti-tumor drugs Dose rounding Drug cost Cost saving Healthcare expenses Economic burden Monoclonal antibody
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Pharmacovigilance analysis of drug-related extrapyramidal symptoms based on the FAERS database

Published on Frontiers in Pharmaceutical Sciences 2025,29(12):2056-2064.
4195 times 1111 times

WU Lihua WANG Huiying CHEN Yangyi PAN Lu RAO Mei

Drug related extrapyramidal symptoms Adverse drug reactions Pharmacovigilance Signal Mining FAERS database Logistic regression
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Research hotspots and trends of Gardenia jasminoides based on bibliometric analysis

Published on Frontiers in Pharmaceutical Sciences 2025,29(12):2046-2055.
4789 times 1071 times

HU Siqi HONG Hailan LIU Wei ZHU Jizhou WAN Na LIU Hongqin WANG Fenghuan LI Hui

Gardenia jasminoides Bibliometrics Research status Hotspot analysis CiteSpace Pharmacological effects Traditional Chinese medicine Network pharmacology
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Effective analysis of adverse drug events and toxicological mechanisms of octreotide based on the FAERS database and network toxicology

Published on Frontiers in Pharmaceutical Sciences 2025,29(12):2036-2045.
4216 times 988 times

WANG Changwen WANG Huiru XU Shibo SUN Fanfan YAN Junzhen

Octreotide Adverse drug events Network toxicology Signal mining FAERS Tumor necrosis factor Ransforming growth factor β Protein-protein interaction
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Construction of a shortage risk early warning model based on risk matrix evaluation and Bayesian belief propagation neural network

Published on Frontiers in Pharmaceutical Sciences 2025,29(12):2027-2035.
4050 times 929 times

SUN Yiyuan LIU Junjiao NI Ying LIANG Liangliang LIU Yunmei ZHAO Guohong ZHANG Jingbo YANG Yang LI Qiang

Drug shortage Drug use monitoring Risk warning Signal detection Bayesian confidence propagation neural network
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Optimization and verification of the inclusion process of volatile oil from Xinyi Tongqiao granules

Published on Frontiers in Pharmaceutical Sciences 2025,29(12):2017-2026.
5028 times 1014 times

ZHU Yuyan LI Ting HUANG Zhijun ZHOU Qi

Xinyi Tongqiao granules β-cyclodextrin Inclusion complexes Volatile oils Patchouli alcohol Saturated water solution method Characterization Orthogonal test
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Exploring the effect of astragalus polysaccharides on adriamycin-induced apoptosis of AC16 cardiomyocytes based on the TGF-β1/Smad3 signaling pathway

Published on Frontiers in Pharmaceutical Sciences 2025,29(12):2009-2016.
3895 times 946 times

WANG Dui DANG Lijuan ZHANG Qiang ZHAO Xiaobin LI Xiaoyu ZHANG Zhengfeng

Astragalus polysaccharides Doxorubicin Myocardial injury TGF-β1/Smad3 signaling pathway Traditional Chinese medicine AC16 Cardiomyocytes Apoptosis
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The multi-target mechanism of Portulaca oleracea's hypoglycemic effect: network pharmacology prediction and molecular docking analysis

Published on Frontiers in Pharmaceutical Sciences 2025,29(12):2000-2008.
4909 times 1013 times

HU Pingping XIA Wei LI Yanpeng CHEN Ting HE Juan

Portulaca oleracea Hypoglycaemia Network pharmacology Molecular docking Quercetin Kaempferol IL-6 TNF AKT1
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Investigating the effects of silibinin on proliferation, apoptosis, migration, invasion, and ferroprelation of HepG2 hepatocellular carcinoma cells based on network pharmacology

Published on Frontiers in Pharmaceutical Sciences 2025,29(12):1990-1999.
4159 times 1046 times

DING Houwei SHENG Hua ZHANG Ping CHEN Meihui

Silibinin Liver cancer Cell proliferation Cell apoptosis Cell migration Cell invasion Ferroptosis Network pharmacology
Details
Integrated network pharmacology and molecular docking to explore the potential molecular mechanisms of diosmin against prostatic hyperplasia complicated with chronic prostatitis

Published on Frontiers in Pharmaceutical Sciences 2025,29(12):1981-1989.
4507 times 1087 times

TANG Liu JIANG Xiao LUO Guangwen WANG Lei

Diosmin Benign prostatic hyperplasia Chronic prostatitis Network pharmacology Molecular docking Signaling pathway GO funnction analysis KEGG pathway analysis
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Signal mining and sex-specific subgroup analysis of donepezil-associated adverse events based on the FAERS database

Published on Chinese Journal of Pharmacoepidemiology 2026,35(1):51-61.
4355 times 1010 times

NING Siming SUN Bao ZOU Hao QI Fengyu YANG Ruixia QIAO Yi

Donepezil FAERS database Adverse drug event Signal mining
Details
Effect of dexmedetomidine on the cognitive function of elderly patients after colorectal cancer surgery: a Meta-analysis

Published on Chinese Journal of Pharmacoepidemiology 2026,35(1):94-103.
4072 times 973 times

ZHAN Qunbo ZHANG Hongfen REN Jing

Dexmedetomidine Colorectal neoplasms Postoperative cognitive dysfunction Meta-analysis Systematic review
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Exploration of the pathways for integrating curriculum ideological and political education into pharmaceutical experiment courses

Published on Journal of Mathematical Medicine 2025,38(12):958-962.
4863 times 998 times

YIN Xinqiang JING Yuanyuan

Curriculum ideological and political education Pharmaceutical experiment Pharmaceutical education Teaching Collaborative education
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Postoperative wound management in adults with anal fistula: best evidence summary

Published on Journal of Mathematical Medicine 2025,38(12):949-957.
7669 times 1261 times

GUO Feng LI Yixuan GAO Jihua GUO Yinfang FENG Jiangxue

Anal fistula Wound management Wound care Wound healing Evidence-based nursing Best evidence
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Analysis of key genes for gemcitabine resistance and their pan-cancer expression, immune infiltration and survival associations

Published on Journal of Mathematical Medicine 2025,38(12):936-948.
4580 times 944 times

SHEN Ruibo YANG Yulin ZHANG Xin LIANG Xinyi YANG Huan DU Juan

Gemcitabine Drug resistance Key genes Pan-cancer Immune infiltration Survival associations
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Exploring the molecular mechanisms of green tea polyphenols against pancreatic adenocarcinoma based on network topology, Bulk transcriptomics and spatial transcriptomics

Published on Journal of Mathematical Medicine 2025,38(12):923-935.
4704 times 1017 times

YANG Yang YANG Jie GUO Baoliang JI Xianhui DAI Ziyun ZHANG Zhirui DU Juan

Green tea polyphenols Pancreatic adenocarcinoma Network topology Bulk transcriptomics Spatial transcriptomics Immune microenvironment
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