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Progress of SNAC for improving oral bioavailability of macromolecular drugs

Published on Frontiers in Pharmaceutical Sciences 2025,29(7):1254-1260.
13989 times 1654 times

SHI Qiongzhi XIE Xiangyang LI Yinke XU Hengjun LIU Hui

SNAC Permeation enhancer Macromolecular drugs Oral bioavailability Drug delivery
Details
Research progress of UPLC-MS technology in the field of traditional Chinese medicine processing

Published on Frontiers in Pharmaceutical Sciences 2025,29(7):1245-1253.
11483 times 1403 times

CAO Xingxing LI Xiaojuan ZHAO Feicui

Ultra-performance liquid chromatography-mass spectrometry Traditional Chinese medicine processing Chemical components Toxic components Pesticide residues Pharmacokinetics Research progress
Details
Research progress on antitumor mechanism of quercetin and its nano formulation

Published on Frontiers in Pharmaceutical Sciences 2025,29(7):1235-1244.
10787 times 1466 times

QIAO Yuenan LI Xin

Quercetin Anti-tumor Mechanism of action Nano formulation
Details
Research progress of flavonoids against injury induced by acute high-altitude hypoxia exposure

Published on Frontiers in Pharmaceutical Sciences 2025,29(7):1224-1234.
10339 times 1284 times

WANG Gege XIN Yu CHEN Keming JING Linlin

Flavonoids High altitude Acute hypobaric hypoxia Oxidative stress Inflammatory response
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Bibliometric analysis of the research hotspots and trends related to Zheng Gan decoction

Published on Frontiers in Pharmaceutical Sciences 2025,29(7):1215-1223.
9846 times 1450 times

SONG Tianli WANG Yiming LIU Xu XIANG Dehuang HUANG Sheng RAN Yun

Bibliometrics Zheng Gan decoction Hepatocellular carcinoma Anti-tumour Apoptosis
Details
Construction and practice of individualized medication guidance for cardiovascular chronic disease patients based on informatization

Published on Frontiers in Pharmaceutical Sciences 2025,29(7):1209-1214.
9147 times 1229 times

YU Tianjian ZHANG Jing YU Xiongjie CHEN Jinhua

Cardiovascular drugs Medication guidance Informatization construction Individuation
Details
Application of QFD innovative quality control circle to construct a management model for chemotherapy-induced vomiting in oncology patients

Published on Frontiers in Pharmaceutical Sciences 2025,29(7):1201-1208.
9968 times 1291 times

ZHANG Menghua MEI Fei XU Jie LI Zhou WANG Wanqing GU Jihong

Chemotherapy-induced nausea and vomiting Quality control circle Quality function deployment Pharmaceutical care
Details
Charcteristics and medication rules in pescriptions of Taiping Huimin Heji Jufang for external preparation based on data mining

Published on Frontiers in Pharmaceutical Sciences 2025,29(7):1192-1200.
9494 times 1261 times

ZHANG Jianjun HE Xueling

Taiping Huimin Heji Jufang External preparations Function characteristics Mian efficacy Medication rules Data mining
Details
Analysis of immune checkpoint inhibitor induced hypothyroidism based on the U.S. FAERS database

Published on Frontiers in Pharmaceutical Sciences 2025,29(7):1186-1191.
9603 times 1283 times

WANG Huiru YANG Hua REN Yanfei CAO Zhibao LI Xue

Immune checkpoint inhibitors Hypothyroidism FDA Adverse Event Reporting System Drug vigilance
Details
Cost-utility analysis of albumin paclitaxel combined with atezolizumab for the treatment of PD-L1-positive advanced triple-negative breast cancer

Published on Frontiers in Pharmaceutical Sciences 2025,29(7):1179-1185.
9842 times 1315 times

HU Xiuping TAN Lunan LI Hongbo YAO Huitao

Albumin paclitaxel Atezolizumab Pharmacoeconomics Cost-utility analysis
Details
Influencing factors of abnormal liver function induced by enoxaparin sodium and construction of Logistic risk prediction model

Published on Frontiers in Pharmaceutical Sciences 2025,29(7):1172-1178.
9614 times 1220 times

ZHOU Xiaoling ZHAO Mengxi HU Yali XU Jing

Enoxaparin sodium Abnormal liver function Risk factors Prediction model Cumulative drug dose
Details
Efficacy and prediction model construction of aripiprazole combined with Sertraline in the treatment of adolescent depression

Published on Frontiers in Pharmaceutical Sciences 2025,29(7):1163-1171.
10675 times 1310 times

YE Haiyan CHEN Liang MIN Guoqing YE Xiaofang

Aripiprazole Sertraline Adolescent depression Treatment efficacy prediction model
Details
Application analysis of butylphthalide combined with programmed intervention in patients with cerebrovascular disease-induced hemiplegia

Published on Frontiers in Pharmaceutical Sciences 2025,29(7):1155-1162.
9580 times 1228 times

WANG Xuelian LIU Ying HU Rui ]LUO Wenjiao

Butylphthalide Programmed intervention Cerebrovascular disease-induced hemiplegia Neurological function Motor ability Self-care ability
Details
Efficacy of Guanxinning combined with nimodipine tablets in the treatment of vascular dementia

Published on Frontiers in Pharmaceutical Sciences 2025,29(7):1147-1154.
10448 times 1244 times

XU An WANG Zhuiqin

Guanxinning Nimodipine tablets Vascular dementia
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Efficacy of Linggui Zhugan formula combined with food restriction therapy on patients with metabolic syndrome

Published on Frontiers in Pharmaceutical Sciences 2025,29(7):1140-1146.
10070 times 1285 times

XIANG Yuyang XIE Yuye JIN Binbin

Linggui Zhugan formula Food restriction therapy Metabolic syndrome Traditional Chinese medicine syndrome Metabolism
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Efficacy of calcitriol soft capsules combined with progressive resistance training in senile sarcopenia

Published on Frontiers in Pharmaceutical Sciences 2025,29(7):1132-1139.
10033 times 1258 times

CHEN Juan CHEN Xiufang WANG Xiaoxue LU Sujuan YE Danru CHEN Wenwen

Calcitriol soft capsules Progressive resistance training Sarcopenia Inflammatory factors
Details
Preparation and characterization of hyaluronic acid-rebamipide conjugate and the conjugate self-assembled nanoparticles

Published on Frontiers in Pharmaceutical Sciences 2025,29(7):1126-1131.
9706 times 1301 times

MAO Kaifan XUE Song WANG Lili LIU Zhengping YANG Xuehua ZHANG Hongqian WANG Yingchao WANG Jinhu LI Dawei

Hyaluronic acid-rebamipide conjugate Rebamipide Nanoparticles
Details
Quality evaluation of Zhike Huatan mixture based on HPLC fingerprint combined with chemometrics

Published on Frontiers in Pharmaceutical Sciences 2025,29(7):1119-1125.
9601 times 1276 times

GUO Hongxing WANG Xianyong CHEN Fei LUO Yiyuan

Zhike Huatan mixture Fingerprint Chemometrics Quality evaluation
Details
Optimization of inclusion process for Ramulus cinnamomi volatile oil using Plackett-Burman design combined with Box-Behnken response surface methodology

Published on Frontiers in Pharmaceutical Sciences 2025,29(7):1108-1118.
10204 times 1328 times

JIANG Mingyue QI Shuang CAO Jixiang LIU Zhenyuan WU Tianqi WANG Changqi BAI Xue HAN Pei ZHANG Wei

Ramulus cinnamomi volatile oil Inclusion process Plackett-Burman Box-Behnken response surface analysis
Details
Geographical variation in seed traits, germination characteristics, and dihydromyricetin content of Hovenia dulcis seeds

Published on Frontiers in Pharmaceutical Sciences 2025,29(7):1099-1107.
9670 times 1269 times

DONG Xiaoxiao CHEN Meizhu XIA Mang CHENG Miao ZENG Changli

Hovenia dulcis Seed traits Germination characteristic High performance liquid chromatography Dihydromyricetin
Details