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Comparison of the efficacy of different fluid resuscitation regimens on traumatic hemorrhagic shock

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):779-786.
7220 times 1086 times

HE Mengxi PAN Aidi CHEN Linglong YE Ru

Fluid resuscitation Therapeutic hypothermia Traumatic hemorrhagic shock
Details
The clinical efficacy of piperacillin-tazobactam sodium combined with budesonide in the treatment of patients with AECOPD

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):772-778.
7408 times 1071 times

WANG Xiaofang WU Yueming PAN Liuhua

Piperacillin-tazobactam sodium Budesonide Acute exacerbation of chronic obstructive pulmonary disease Inflammatory factors
Details
Effect of GnRH antagonist combined with rLH on IVF outcomes in patients with low LH levels

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):764-771.
6809 times 1028 times

CHEN Mei YANG Lihua WANG Rong

Gonadotropin-releasing hormone antagonist Recombinant luteinizing hormone Low luteinizing hormone Ovarian responsiveness In vitro fertilization pregnancy
Details
Feasibility study on mercury-free green testing of hydrochloride salt drugs in the Chinese Pharmacopoeia

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):756-763.
7164 times 1144 times

LIU Huiying LI Shangying HUANG Hai XU Wankui

Hydrochloride drugs Method substitution Mercury salt elimination Green drug testing Quality control
Details
Optimization of the matrix formulation of Shangjin Zhitong gel patch by Box-Behnken response surface methodology

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):747-755.
7779 times 1095 times

LONG Zechun LIU Yang SHI Qiongzhi LIU Hui XIONG Chengjie HU Hua

Shangjin Zhitong gel Gel patch Formulation optimization Box-Behnken response surface methodology
Details
Protection mechanism of myocardial tissues of Wnt/β-catenin signaling inhibition by GAS5 in rats with coronary artery disease

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):739-746.
7811 times 1054 times

WANG Qunye LI Chunhong XU Lu

Growth arrest-specific 5 Wnt/β-catenin signaling pathway Coronary heart disease Myocardial injury Myocardial enzymes Apoptosis
Details
Mechanism of Xianju Xiaozhen decoction in treating atopic dermatitis based on network pharmacology and molecular docking

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):730-738.
6998 times 1136 times

CHEN Wendong ZHOU Chao XU Xinchang FENG Shuhang GUAN Jiaqi WANG Lei ZHA Weifeng

Xianju Xiaozhen decoction Atopic dermatitis Molecular mechanism Network pharmacology Molecular docking
Details
The effect of butylphthalein regulating the PI3K/Akt/CREB signaling pathway on cisplatin-induced inflammation and apoptosis in PC12 cells

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):721-729.
6716 times 1114 times

YAO Mengyuan WEN Min HUANG Zhengyuan CHEN Peng ZHOU Benhong

Butylphthalide Neuroprotection Apoptosis Chemotherapy-related cognitive impairment PC12 cells
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Analysis of a case of 5-hydroxytryptamine syndrome caused by oxycodone hydrochloride sustained-release tablets

Published on Chinese Journal of Pharmacoepidemiology 2025,34(6):715-719.
11591 times 3371 times

ZHANG Mengyu XING Xiaomin WANG Jikai LI Jinfeng ZHANG Yuan JING Fanbo

Oxycodone hydrochloride sustained-release tablets 5-Hydroxytryptamine Syndrome Morphine sulfate sustained-release tablets Adverse drug reaction
Details
Subcutaneous hematoma complicated with rhabdomyolysis caused by sudden overdose of warfarin: a case report

Published on Chinese Journal of Pharmacoepidemiology 2025,34(6):720-724.
10526 times 3310 times

ZHAO Yinping ZHAO Xiuping QIN Xialing HE Haihua DAI Tao

Warfarin Subcutaneous hematoma Rhabdomyolysis Medication errors
Details
Pharmaceutical care of a child with high-risk neuroblastoma using naxitamab

Published on Chinese Journal of Pharmacoepidemiology 2025,34(5):595-599.
11860 times 3010 times

CHEN Yin LIU Xin YU Liting ZHANG Min

Neuroblastoma Naxitamab Adverse drug reaction Pharmaceutical care Pain
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The research progress of siRNA drugs in obesity

Published on Chinese Journal of Pharmacoepidemiology 2025,34(5):589-594.
14960 times 3640 times

JIANG Fengxuan LU Qingmiao LU Yibing

siRNA drugs Obesity Weight loss Delivery system
Details
Efficacy and safety of azithromycin versus amoxicillin and clavulanate potassium in the treatment of children with otitis media: a systematic review and Meta-analysis

Published on Chinese Journal of Pharmacoepidemiology 2025,34(5):567-577.
12252 times 2957 times

JIAN Jiejun LI Ni CHEN Zhe YU Zizhong

Azithromycin Amoxicillin and clavulanate potassium Otitis media Meta-analysis Systematic review Randomized controlled trial
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Evidence map analysis of Chinese medicine treatment of premature ovarian insufficiency

Published on Chinese Journal of Pharmacoepidemiology 2025,34(5):556-566.
13949 times 3055 times

CHEN Kan WAN Li WANG Fang LIU Yingxue TANG Jinyan HAN Lu

Traditional Chinese medicine Premature ovarian insufficiency Meta-analysis Evidence map Overview of systematic review
Details
Study on the effect of fumigation decoction on the expression of aggrecan and type II collagen in a rat model of intervertebral disc degeneration

Published on Chinese Journal of Pharmacoepidemiology 2025,34(5):548-555.
11334 times 3132 times

XIONG Guang DONG Chenpeng YANG Guoyu XU Zhiqiang WU Xinghuo

Fumigation decoction Fumigation Intervertebral disc degeneration Aggrecan Type II collagen Lumbar degenerative diseases
Details
Evaluation of off-label use of flupentixol melitracen based on evidence-based medicine

Published on Chinese Journal of Pharmacoepidemiology 2025,34(5):539-547.
15257 times 3923 times

WANG Chuanquan CAO Di ZHANG Shiyang

Flupentixol melitracen Evidence-based medicine Gastritis Vertigo Off-label drug use
Details
Effect of butylphthalide on the risk of post-stroke epilepsy in patients with cerebral infarction

Published on Chinese Journal of Pharmacoepidemiology 2025,34(5):532-538.
12065 times 3093 times

YU Qi YUAN Junfeng CHEN Kai LI Xiuyun LI Zhanyong

Butylphthalide Cerebral infarction Post-stroke epilepsy
Details
Analysis of the correlation between glucocorticoids and prognosis of severe viral pneumonia patients

Published on Chinese Journal of Pharmacoepidemiology 2025,34(5):524-531.
14278 times 3184 times

WU Xiayang HONG Suru CHEN Yushuang SU Yanqing

Glucocorticoids Severe viral pneumonia Prognosis Survival analysis MIMIC-Ⅳ database
Details
Signal mining and analysis of adverse events of basiliximab used in solid organ transplantation based on FAERS database

Published on Chinese Journal of Pharmacoepidemiology 2025,34(5):515-523.
13849 times 3366 times

CHENG Saisai ZHU Feng ZHOU Bi

Basiliximab Solid organ transplantation Adverse drug event FAERS database Data mining
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Clinical characteristics and drug resistance analysis of 408 patients with Escherichia coli bloodstream infection

Published on Chinese Journal of Pharmacoepidemiology 2025,34(5):507-514.
14486 times 3254 times

HU Peng CAI Tongjian WANG Yi CHENG Yao LIU Qiuqian XIAO Hong

Bloodstream infection Escherichia coli Extended-spectrum β-lactamases Clinical features Drug resistance
Details