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Popular literature

Predictive analysis of quality markers of Poria cocos based on fingerprint and network pharmacology

Published on Frontiers in Pharmaceutical Sciences 2025,29(9):1482-1491.
2666 times 354 times

HUANG Guangwei HOU Li WU Xinhua

Poria cocos Fingerprint Chemical pattern recognition Network pharmacology Molecular docking Quality marker
Details
Mechanism of agiophyllum oligo saccharides in improving type 2 diabetes mellitus related liver injury based on proteomics method

Published on Frontiers in Pharmaceutical Sciences 2025,29(8):1261-1270.
2656 times 548 times

ZHANG Zihan ZHANG Xiaojie YANG Yuze YANG Tianshuo XING Dongyang MA Qianqian BAO Shuyin

Agiophyllum oligo saccharides Type 2 diabetes mellitus Liver injury Proteomics
Details
A case report of acute kidney injury associated with pegylated recombinant human granulocyte colony-stimulating factor injection

Published on Chinese Journal of Pharmacoepidemiology 2025,34(9):1104-1107.
2653 times 610 times

ZHONG Hong QIU Hongbo ZHANG Xuanyi KONG Wenqiang

Pegylated recombinant human granulocyte colony-stimulating factor Acute kidney injury Adverse drug reaction
Details
Study on the integrated processing technology of Isatidis radix based on response surface method

Published on Frontiers in Pharmaceutical Sciences 2025,29(8):1288-1295.
2647 times 504 times

LU Shasha WANG Ning WANG Yumei BAI Zhongjie HE Yuanyuan DAI Wenqian

Isatidis radix Integrated processing and processing of origin Response surface method High performance liquid chromatography
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Mining of adverse reaction signals of amlodipine based on the FAERS database and the construction of a digital and intelligent pharmacovigilance platform

Published on Chinese Journal of Pharmacoepidemiology 2025,34(8):846-854.
2641 times 649 times

HU Yanghui QIU Ziyan ZHANG Bingsong

Amlodipine Adverse drug event Signal mining FAERS database Digital intelligent platform
Details
Study on the mechanism of Runzao Zhiyang capsule in the treatment of atopic dermatitis based on UPLC-MS/MS and network pharmacology combined with molecular docking

Published on Frontiers in Pharmaceutical Sciences 2025,29(9):1460-1468.
2638 times 342 times

HOU Suyue LI Mengmeng WU Guijuan WANG Chun TANG Liu

Runzao Zhiyang capsule Atopic dermatitis Ultra performance liquid chromatography tandem mass spectrometry Network Pharmacology Mechanisms
Details
Tetrahydropalmatine activates the Nrf2/ARE pathway to alleviate oxidative stress and improve high glucose-induced insulin resistance in HepG2 cells

Published on Frontiers in Pharmaceutical Sciences 2025,29(8):1360-1367.
2618 times 402 times

YE Xiaoting CHEN Xiaohai XU Shuang

Tetrahydropalmatine HepG2 Insulin resistance Nrf2/ARE Oxidative stress
Details
Mechanism of houttuynia cordata aqueous extract inhibiting endotoxin-induced uveitis in rats based on the anti-inflammatory signaling pathways of PI3K, Wnt and NF-κB

Published on Frontiers in Pharmaceutical Sciences 2025,29(8):1271-1279.
2595 times 459 times

ZHANG Cheng GAO Chenfei FEI Chunxia QU Fei

Houttuynia cordata aqueous extract Uveitis Inflammatory factor PI3K/AKT/mTOR Wnt/β-catenin NF-κB/MAPK
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Research progress on big-data-driven analysis strategies for imbalanced data of rare events

Published on Chinese Journal of Pharmacoepidemiology 2025,34(8):952-961.
2568 times 612 times

ZHOU Jiangjie WANG Yutong FENG Tian MENG Xianglong LIANG Baosheng WANG Shengfeng

Rare events Imbalanced data Data-driven Deep learning
Details
Influence of external application of modified Qingliang Huohua powder at different temperatures on patients with damp-heat accumulation type of knee osteoarthritis

Published on Frontiers in Pharmaceutical Sciences 2025,29(8):1336-1342.
2537 times 411 times

SHU Qiongyan YE Haixia FENG Yanqin WANG Jian ZHAO Wanjun WANG Junjie

Modified qingliang huohua powder Knee osteoarthritis Temperature External application Damp-heat accumulation type
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Application status and development prospect of digital intelligence technology in the diagnosis and treatment of rare diseases

Published on Chinese Journal of Pharmacoepidemiology 2025,34(8):972-985.
2535 times 590 times

YANG Yujie QI Leyuan CAO Yanbo WEN Xiaotian LIU Jicong CHEN Bixiao LIU Yawei HE Guohua TIAN Yu

Rare diseases Digital intelligence Full life-cycle
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Clinical observation on the efficacy of sacral-4 acupuncture therapy combined with tadalafil in the treatment of erectile dysfunction

Published on Frontiers in Pharmaceutical Sciences 2025,29(9):1516-1522.
2525 times 349 times

WANG Yongwei ZHAO Liangwei LI Shenghua

Erectile dysfunction Sacral-4 acupuncture Tadalafil Pudendal nerve electrical stimulation International index of erectile function Erection hardness score
Details
Construction of a prediction model for medication non-adherence of anti- parkinsonian drugs in patients with Parkinson's disease

Published on Frontiers in Pharmaceutical Sciences 2025,29(8):1343-1351.
2503 times 408 times

JI Yuanyuan ZHANG Xiaobei [FLJ

Parkinson's disease Medication adherence Influencing factors Prediction model
Details
Research progress on the role and mechanism of Chitooligosaccharides in improving metabolic dysfunction-associated fatty liver disease

Published on Frontiers in Pharmaceutical Sciences 2025,29(8):1422-1430.
2496 times 420 times

ZHONG Li HUANG Guidong

Chitooligosaccharides Metabolic dysfunction-associated fatty liver disease Lipid-Lowering mechanism Research progress
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The disease burden of infertility in China from 1992 to 2021 based on an age-period-cohort model

Published on New Medicine 2025,35(9):1041-1047.
2485 times 453 times

HUANG Bingyi ZHAO Qin YAO Libo WANG Manyi ZHAO Qianwen

Infertility Burden of disease Prevalence Age-period-cohort model
Details
Observation on the efficacy of Huoluo Xiaotong capsules in treating cervical spondylosis radiculopathy: a real-world study

Published on Chinese Journal of Pharmacoepidemiology 2025,34(9):1025-1031.
2479 times 436 times

LAN Xiangzhou ZENG Weike ZHOU Shasha KUANG Gaoyan GUO Cheng CHEN Qing

Cervical spondylosis radiculopathy Huoluo Xiaotong capsules Real-world study Efficacy evaluation
Details
Cognitive trajectories modeling of rare reversion in mild cognitive impairment

Published on Chinese Journal of Pharmacoepidemiology 2025,34(8):877-886.
2476 times 624 times

QIN Yao HUO Yanji ZHOU Jing ZHOU Yan HAN Hongjuan CUI Jing YU Hongmei

Mild cognitive impairment Reversion Rare events Functional principal component analysis Multi-state model
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Perioperative rare adverse reactions discovery: real-world data foundations and methodological advances

Published on Chinese Journal of Pharmacoepidemiology 2025,34(8):917-925.
2462 times 579 times

YIN Xuan HUANG Ruijian KONG Siyu ZHOU Jifang

Adverse drug reaction Perioperative Pharmacovigilance Digital and intelligent integration Real-world study Methodology
Details
The association of sodium benzoate and the potential risk of benzene contamination in oral liquid preparations

Published on Frontiers in Pharmaceutical Sciences 2025,29(8):1321-1328.
2451 times 425 times

SUN Li HUANG Ping ZHANG Rong WU Min

Oral liquid preparations Sodium benzoate Benzene Headspace gas chromatography–mass spectrometry Risk evaluation
Details
Relationship between the ratio of non-HDL-C and HDL-C and the risk of all-cause mortality in a population with abnormal glucose metabolism: base on CHARLS database

Published on New Medicine 2025,35(8):878-884.
2447 times 648 times

ZHANG Jie FANG Kui CHEN Hongyan

Non-high density lipoprotein cholesterol High density lipoprotein cholesterol NHHR Abnormal glucose metabolism Dyslipidemia Risk of all-cause mortality Cohort studies
Details