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Structure-activity characteristics and safety signal analysis of thrombopoietin receptor agonists

Published on Chinese Journal of Pharmacoepidemiology 2026,35(4):398-408.
2199 times 617 times

YAN Qianci SHANG Nan YUE Xiunan CHEN Wanying ZHENG Xiaojun

Thrombopoietin receptor agonists Immune thrombocytopenia Quantitative structure-activity relationship Network pharmacology Pharmacovigilance
Details
Bibliometric analysis of ethical review of clinical research in the context of public health emergency caused by emerging infectious diseases in China

Published on Journal of Mathematical Medicine 2026,39(5):328-338.
2175 times 584 times

LIU Lu CAO Lili

Emerging infectious diseases Clinical research Ethical review Bibliometrics
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Research progress on the hepatoprotective effects and safety evaluation of sophocarpine

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):692-698.
2166 times 531 times

JIANG Jingjing WANG Changlin SONG Chunhong LI Yanan

Sophocarpine Hepatoprotective effect Safety evaluation Lipid metabolism An-ti-fibrosis Anti-inflammatory Anti-tumor Hepatotoxicity Acute toxicity
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Comparative analysis of antibacterial activity of Perilla Folium with different leaf colors and its correlation with leaf color values and chemical constituents

Published on Frontiers in Pharmaceutical Sciences 2026,30(5):787-794.
2159 times 440 times

LIU Wenli YANG Meiqin LI Lingxi NIE Lixing KANG Shuai YU Jiandong CHENG Xianlong LIN Yongqiang WEI Feng

Perilla Folium Antibacterial activity Color values Chemical composition Correlation
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Optimization of fresh-cutting processing for Cistanche deserticola using AHP-CRITIC method combined with Box-Behnken design-response surface method

Published on Frontiers in Pharmaceutical Sciences 2026,30(5):759-766.
2140 times 396 times

LIU Zhaofu XU Lifang HU Xiaoli LI Junxian DENG Kun YE Xide ZHONG Lingyun

Cistanche deserticola Fresh-cutting Analytic hierarchy process-criteria importance through intercriteria correlation method Box-Behnken design-response surface method Echinacoside Verbascoside
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Experimental study on the protective effect and safety of different doses of quercetin on the intestinal barrier in sepsis

Published on Chinese Journal of Pharmacoepidemiology 2026,35(5):517-525.
2140 times 576 times

FENG Mingzhi SUN Yan ZHANG Jun

Quercetin Sepsis Intestinal epithelial barrier Anti-inflammatory Infection
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Giant hepatocellular adenoma in an adolescent male: a case report

Published on Journal of Mathematical Medicine 2026,39(5):388-392.
2132 times 610 times

CAI Ao ZHOU Rui

Hepatocellular adenoma Adolescent male Laparoscopic hemihepatectomy Focal nodular hyperplasia Hepatic adenomatosis Hepatic artery embolization
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Environmental chemical exposure and antidepressant efficacy: mechanisms and advances in precision pharmacology prediction models

Published on Chinese Journal of Pharmacoepidemiology 2026,35(5): 579-588.
2120 times 462 times

WANG Pei CHEN Wanying SHANG Nan ZHANG Ruifen

Antidepressants Environmental exposure Blood-brain barrier Drug efficacy Envir-onmental chemical pollutants Precision pharmacology
Details
Retrospective study on the efficacy of insulin degludec/insulin aspart combined with dietary management in patients with type 2 diabetes mellitus

Published on Frontiers in Pharmaceutical Sciences 2026,30(5):813-819.
2103 times 427 times

XIANG Yuyang XIE Yuye LIN Zhihao

Type 2 diabetes mellitus Insulin degludec/insulin aspart Integrated diet management model Efficacy observation
Details
Visualization analysis of off-label drug use of Chinese patent medicine based on CiteSpace software

Published on Chinese Journal of Pharmacoepidemiology 2026,35(5):563-570.
2094 times 585 times

SONG Yifei WANG Hui YANG Wenbao CHEN Xin JIA Shengwei ZHANG Huiyue

Chinese patent medicine Off-label use Bibliometrics Visual analysis Rational drug use
Details
Association between oxygenation status and pressure injury in intensive care unit patients: a Meta-analysis

Published on New Medicine 2026,36(4):457-463.
2086 times 763 times

DONG Pingping LIU Fangfang CAO Hunan

Pressure injury Intensive care unit Arterial partial pressure of oxygen Meta-Analysis
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Study on the authenticity identification of Fructus Viticis Negundo and the quality transfer law of decoction pieces to standard decoction based on UPLC characteristic chromatogram and multi-index content determination

Published on Frontiers in Pharmaceutical Sciences 2026,30(5):777-786.
2079 times 505 times

HE Jiaying WU Wenping LIN Han ZHONG Chunlin SUO Caixian LIU Xiaohan LI Guowei CHEN Xiangdong SUN Dongmei

Fructus Viticis Negundo Vitex Fructus Standard decoction Characteristic chromatogram Content determination Quality and quantity transfer Cluster analysis Partial least squares discriminant analysis
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Multi-strategy exploration on the molecular mechanism of Paeonia Radix Rubra against endometrial carcinoma by integrating multi-omics and computational simulation

Published on Frontiers in Pharmaceutical Sciences 2026,30(5):721-736.
2076 times 467 times

ZHANG Xueke BAI Haozhen CHEN Mengjia GAO Xinyi HU Yufan XIE Jumin WAN Shuqiong

Paeonia Radix Rubra Endometrial carcinoma Molecular dynamics simulation Baicalein Breast cancer resistance protein Insulin receptor PI3k/Akt Tumor microenvironment
Details
Signal mining and analysis of adverse events associated with the use of beta-1 blockers in children based on the FAERS database

Published on Chinese Journal of Pharmacoepidemiology 2026,35(5):542-552.
2067 times 559 times

CHANG Qiuyue SHANG Shenglan ZHAO Yan YU Mengchen YU Airong

Metoprolol Bisoprolol Atenolol Esmolol Adverse drug events Signal mining Pharmacovigilance
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Analysis of one case of almolertinib-induced interstitial lung disease in a lung cancer patient

Published on Frontiers in Pharmaceutical Sciences 2026,30(5):895-900.
2031 times 416 times

FAN Xinxing LI Ling ZHENG Menying BAI Juan

Almonertinib Interstitial lung disease Lung cancer Adverse drug reaction
Details
Investigation of the mechanisms of action of Shuanghuanglian in treating res-piratory syncytial virus infection based on network pharmacology, molecular docking and molecular dynamics simulations

Published on Frontiers in Pharmaceutical Sciences 2026,30(5):737-747.
2028 times 407 times

REN Shuanshan ZHANG Yuqin MOU Jing YIN Shuqing WANG Lingling

Shuanghuanglian Respiratory syncytial virus GEO data Network pharmacology Molecular docking Molecular dynamics simulation Protein-protein interaction
Details
The effect of virtual reality technology on symptoms and quality of life in multiple sclerosis patients: a Meta-analysis

Published on Journal of Mathematical Medicine 2026,39(5):373-382.
2027 times 551 times

WANG Qingyuan YUAN Hong MING Xiangying LIN Lunwei ZHOU Ye MA Li

Multiple sclerosis Virtual reality Cognitive function Quality of life Meta-analysis
Details
Establishment of drug utilization evaluation criteria for bemiparin sodium and its clinical application

Published on Frontiers in Pharmaceutical Sciences 2026,30(5):820-827.
2013 times 443 times

YE Chenli HONG Weimin HAN Yutong CAO Weiling

Bemiparin sodium Drug utilization evaluation Delphi method Off-label use Rational drug use
Details
Impact of interactive devices in nursing on the motor ability of patients with ischemic stroke: a systematic review and Meta-analysis

Published on New Medicine 2026,36(5):567-573.
2013 times 455 times

ZHANG Xiaoxia WANG Wenfang MA Hongmei

Ischemic stroke Virtual reality Brain-computer interface Nursing model Meta-analysis
Details
Multi-component determination and chemometric quality evaluation of Rhododendron anthopogonoides

Published on Frontiers in Pharmaceutical Sciences 2026,30(5):767-776.
2009 times 421 times

ZHANG Rui XU Sisi TIAN Yongqiang FAN Minxia

Rhododendron anthopogonoides TLC HPLC Flavonoids Principal component analysis Quality evaluation
Details