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Influencing factors of the therapeutic effect of PD-1 inhibitor pembrolizumab on cervical cancer

Published on Frontiers in Pharmaceutical Sciences 2024,27(8):1375-1382.
8499 times 1640 times

HU Jinghua SANG Xuemei QIAO Wei ZHANG Miao

Programmed death-1 Programmed death-ligand 1 Pabolizumab Cervical carcinoma Tumor mutation burden Tumor infiltrating lymphocytes Neoantigen intra-tumoral heterogeneity
Details
Efficacy of postoperative self-controlled analgesia pump with esketamine after colorectal cancer radical surgery on the psychological status and early cognitive function of elderly patients

Published on Frontiers in Pharmaceutical Sciences 2024,27(8):1368-1374.
8457 times 1706 times

HE Han WANG Huide WU Ruigang ZHONG Qing

Esketamine Sufentanil Self-controlled analgesic pump Colorectal cancer Psychological state Early cognitive function
Details
Effect of metformin in patients with obese polycystic ovary infertility

Published on Frontiers in Pharmaceutical Sciences 2024,27(8):1360-1367.
8314 times 1571 times

ZHU Mengni TIAN Ping XU Hui GUO Jian

Metformin Obesity Polycystic ovary syndrome Infertility Clinical efficacy Reproduction Pregnancy Glucolipid metabolism
Details
Clinical efficacy and safety of azithromycin sequential therapy combined with risk management in the treatment of mycoplasma pneumoniae pneumonia in children

Published on Frontiers in Pharmaceutical Sciences 2024,27(8):1353-1359.
8619 times 1507 times

WANG Yongmei GONG Min XU Meiyan JIANG Rong

Azithromycin Risk management Mycoplasma pneumoniae pneumonia Inflammatory cytokines Drug related adverse reactions Nursing Satisfaction
Details
Efficacy of low molecular weight heparin combined with intervention of integrated medical-nursing enhanced recovery after surgery in preventing deep vein thrombosis after colorectal cancer surgery

Published on Frontiers in Pharmaceutical Sciences 2024,27(8):1343-1352.
7989 times 1591 times

WU Lili ZHANG Yantao

Low molecular weight heparin Integrated medical-nursing Enhanced recovery after surgery Deep vein thrombosis Colorectal cancer Thrombosis prevention
Details
Efficacy and safety of tislelizumab combined with sorafenib in the treatment for unresectable hepatocellular carcinoma

Published on Frontiers in Pharmaceutical Sciences 2024,27(8):1136-1342.
8795 times 1659 times

JIANG Jinghua HU Yiting

Tirilizumab Sorafenib Unresectable Hepatocellular carcinoma Objective response rate Disease control rate Progression-free survival Overall survival
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Application value of papaverine combined with staged rehabilitation in patients after free flap transplantation for hand trauma

Published on Frontiers in Pharmaceutical Sciences 2024,27(8):1327-1335.
8528 times 1655 times

ZHANG Yuehong JIANG Chunyan ZHAO Xueyan ZHONG Su XUE Chunmei CHEN Xuanchen

Papaverine Stage rehabilitation Hand trauma Postoperative rehabilitation Free flap
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Clinical effect of bone melon extract combined with loronoxicam in elderly patients after total hip arthroplasty

Published on Frontiers in Pharmaceutical Sciences 2024,27(8):1320-1326.
8480 times 1635 times

ZHANG Kaili FAN Xin SUN Lingtong

Bone melon extract Clonoxicam Total hip arthroplasty Efficacy Femoral neck fracture Elderly C-reactive protein Tumor necrosis factor-α
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Application of micro-macroscopical identification in quality acceptance of Chinese herbal pieces in medical institutions

Published on Frontiers in Pharmaceutical Sciences 2024,27(8):1309-1319.
10657 times 2143 times

ZHANG Lulu LOU Zhaohuan ZHU Xuemei CHEN Yongcai ZHU Jingjing HUANG Leyan

Micro-macroscopical identification Chinese herbal pieces Quality acceptance Application value Pharmacy administration Medical institution Eriocauli flos Aurantii fructus Chaenomelis fructus Perillae fructus Astragali complanati semen Selaginellae herba Lysimachiae herba Cyrtomium fortunei Root of Valvate actinidi
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Determination of element impurities in medicinal excipient potassium sorbate by ICP-MS

Published on Frontiers in Pharmaceutical Sciences 2024,27(8):1303-1308.
8411 times 1794 times

PANG Sai JIANG Kun WANG Ping

Potassium sorbate Medicinal excipient Inductively coupled plasma-mass spectrometry Element impurities The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use Q3D
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Research on the rheological properties of terbinafine hydrochloride cream

Published on Frontiers in Pharmaceutical Sciences 2024,27(8):1296-1302.
10905 times 2118 times

CHEN Qianqian LIU Zhengping LI Shuolei XUE Song LI Dawei

Terbinafine hydrochloride cream Rheology Original drug Generic drug Yield stress Viscosity Modulus Creep recovery
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Extraction process optimization of naphthoquinone from Walnut green husk based on Box-Behnken design-response surface methodology and back propagation neural network

Published on Frontiers in Pharmaceutical Sciences 2024,27(8):1286-1295.
8422 times 1710 times

GAO Jie MA Jingyi

Walnut green husk Naphthoquinone Extraction process optimization Box-Behnken design-response surface methodology Neural network In vitro antioxidant
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Mechanism of "Astragalus-Leech" medicine pair for treatment of cerebral ischemia-reperfusion injury by regulating ferroptosis

Published on Frontiers in Pharmaceutical Sciences 2024,27(8):1273-1285.
9563 times 1937 times

YANG Zhiqian JIANG Jie LIU Wei WANG Jingju YANG Hong

Astragalus Leech Network pharmacology Molecular docking Cerebral ischemia-reperfusion injury Ferroptosis Oxidative stress Inflammation Mechanism
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Current situation and reform trend of medical practical course teaching mode in the "AI+Education" era

Published on New Medicine 2024,34(8):950-956.
21998 times 3397 times

CHENG Shan CONG Lin HU Wendong XIONG Kaiwen MA Jin

Artificial intelligence Medical practice course Teaching reform Teaching concept Accurate evaluation Thinking training
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A case report of the treatment and nursing of diabetic foot ulcers complicated with infection

Published on New Medicine 2024,34(8):943-949.
9951 times 2153 times

HUANG Yugu ZHANG Juyun MENG Xubiao HUANG Chanjuan

Diabetic foot ulcers Treatment plan Multi-dimensional comprehensive nursing Case report
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Research progress on the role and treatment of CD24 in the tumor microenvironment

Published on New Medicine 2024,34(8):936-942.
10971 times 2343 times

YU Xinjing QIAO Xiaojuan

CD24 Tumor microenvironment Malignant tumors
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Characteristics of lower limb surface electromyography in patients with knee osteoarthritis and progress in their exercise rehabilitation

Published on New Medicine 2024,34(8):927-935.
12936 times 2042 times

SHAO Yunbo GUO Jiayi LI Feng LI Jianqiang YAO Kexin

Knee osteoarthritis Degenerative joint disease Surface electromyography Sports rehabilitation Quadriceps muscle
Details
Efficacy and safety of sacubitril/valsartan in the treatment of atrial fibrillation after ablation: a Meta-analysis

Published on New Medicine 2024,34(8):916-926.
11015 times 2107 times

BI Longfei LIU Yao YU Dan DAN Xuechuan LI Kui

Sacubitril/valsartan Atrial fibrillation Angiotensin converting enzyme inhibitors Angiotensin receptor blockers Ablation Meta-analysis
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An analysis of the latent classification and influencing factors of the characteristic symptoms in patients with maintenance hemodialysis

Published on New Medicine 2024,34(8):906-915.
13900 times 2145 times

FENG Meiqin CHEN Hongfang ZHANG Jiayang ZHANG Layin

Maintenance hemodialysis Symptom Latent profile analysis Influencing factor
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Relationship between the serum miR-21, PANDER, PAPP-A levels and adverse pregnancy outcomes in gestational diabetes mellitus

Published on New Medicine 2024,34(8):897-905.
8949 times 1803 times

JIANG Chunrong TANG Minxin LI Chen ZHANG Pei

Gestational diabetes mellitus Adverse pregnancy outcomes Pancreatic derived factor Pregnancy-associated plasma protein A MicroRNA-21
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