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Wuhan University
Zhongnan Hospital of Wuhan University
Center for Evidence-Based and Translational Medicine of Wuhan University
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A total of
2251
result was found. Results
Research advances in targeted protein degradation technologies
Published on
New Medicine
2026,36(4):464-470.
657 times
202 times
PI Chuan
HAO Xuanrun
XIAO Haiting
LUO Xing
ZHANG Qixiong
Targeted protein degradation
Proteolysis targeting chimera
Molecular glue
Lysosome-targeting chimera
Autophagy-targeting chimera
Autophagosome-tethering compound
Details
Research advances in metabolic reprogramming-mediated macrophage polarization in gout
Published on
New Medicine
2026,36(4):471-478.
617 times
188 times
LIU Xinru
YAN Jin
MA Jing
LI Chunlei
MAN Dafu
LI Huilin
DA Gula
ZHAO Jing
WANG Jing
LI Hongbin
HOU Yunxia
WANG Yong
Gout
Metabolic reprogramming
Macrophage polarization
Glycolysis
Details
Exploration and reflection on evidence-based medicine teaching for practical training of research capacity in medical undergraduates under the "five-dimensional" paradigm
Published on
New Medicine
2026,36(4):479-486.
1728 times
201 times
LI Zhenxin
WU Junru
ZHUANG Quan
YUAN Hong
LU Yao
CAI Jingjing
Clinical medicine undergraduates
Evidence-based medicine
Educational reform
Research capability development
Teaching model
Details
Mechanism of formulas containing the Astragali Radix-Anemarrhenae Rhizoma herb pair in treating chronic heart failure based on Apriori algorithm, network pharmacology, and molecular docking
Published on
Frontiers in Pharmaceutical Sciences
2026,30(4):541-554.
1095 times
242 times
ZHANG Mengqian
PANG Jianying
WANG Chaohui
HOU Jiahao
ZHANG Yajing
LI Jing
SONG Yongxing
MA Donglai
Chronic heart failure
Astragali Radix-Anemarrhenae Rhizoma
Herb pair
Apriori algorithm
Network pharmacology
Molecular docking
Details
Mechanism of Gualou Xiebai decoction in treating myocardial infarction based on UPLC-Orbitrap-MS/MS and network pharmacology
Published on
Frontiers in Pharmaceutical Sciences
2026,30(4):555-565.
933 times
228 times
YAN Muxian
LAN Yikun
ZHOU Yaliang
TAN Wanchuang
LIN Junjie
Gualou Xiebai decoction
Myocardial infarction
Network pharmacology
Ul-tra-performance liquid chromatography-orbitrap tandem mass spectrometry
Mechanism of action
Active components
Target prediction
Details
Target screening and efficacy evaluation of lotusine against pancreatic cancer: prediction based on network pharmacology and validation by animal experiments
Published on
Frontiers in Pharmaceutical Sciences
2026,30(4):566-574.
875 times
228 times
QI Fei
CHEN Qi
Lotusine
Pancreatic cancer
Network pharmacology
Therapeutic targets
Molecular docking
Animal experiment
GO functional enrichment analysis
KEGG pathway enrichment analysis
Details
Mechanism of bisphenol A regulating the immune microenvironment of atopic dermatitis through the BPA/HRH1 axis
Published on
Frontiers in Pharmaceutical Sciences
2026,30(4):575-583.
888 times
204 times
LI Chunhua
LIANG Qinghua
FU Qinqin
ZHAO Kaizheng
LU Jun
Bisphenol A
Atopic dermatitis
Endocrine disruptor
Immune microenvironment
Histamine receptor H1
Lymphocyte-specific protein tyrosine kinase
Platelet-activating factor receptor
Details
Study on the material basis and mechanism of Gualou Xiebai Banxia decoction in promoting mitophagy to ameliorate myocardial hypoxia/reoxygenation injury
Published on
Frontiers in Pharmaceutical Sciences
2026,30(4):584-594.
1015 times
253 times
ZHU Jiaxuan
SONG Xiansheng
YANG Ziqi
XIAN Leyao
ZHOU Hua
HE Fan
HUANG Yufeng
Gualou Xiebai Banxia decoction
Chrysoeriol
Hypoxia/reoxygenation myocardial cell injury
Mitophagy
Apoptosis
Caspase-3
Parkin
FUNDC1
Details
Comparative study of the pharmacokinetics of Abelmoschus manihot (L.) Medic. flowers in directly taken decoction pieces and traditional decoction pieces of hyperoside in normal and nephrotic syndrome rats
Published on
Frontiers in Pharmaceutical Sciences
2026,30(4):595-602.
878 times
196 times
NIU Kailin
LUO Heng
ZHOU Jing
BAI Xiaolu
WEN Qing
CHEN Chu
WU Yan
ZHANG Hong
MENG Huix-in
ZHANG Lei
Abelmoschus manihot (L.) Medic.
Hyperoside
Nephrotic syndrome
Directly taken decoction pieces
Traditional decoction pieces
HPLC-QqQ/MS
Pharmacokinetics
Drug metabolism
Rats
Details
Analysis and evaluation of inorganic elements in Rhododendron anthopogonoides Maxim. from different regions
Published on
Frontiers in Pharmaceutical Sciences
2026,30(4):603-612.
852 times
180 times
XU Sisi
ZHANG Rui
WANG Kefeng
FAN Minxia
TIAN Yongqiang
Rhododendron anthopogonoides Maxim.
Inorganic elements
ICP-AES
ICP-MS
FAAS
Details
Correlation study of ferulic acid and ligustilide levels with plant growth regulator residues in Angelica sinensis
Published on
Frontiers in Pharmaceutical Sciences
2026,30(4):613-623.
941 times
203 times
ZHANG Shengjie
MA Yantao
ZHAO Shangyi
JIA Jinru
MA Xiao
LI Donghua
Angelica sinensis
Ferulic acid
Ligustilide
Plant growth regulator
Residues
Dose-effect relationship
Details
Optimization of extraction process for total polyphenols from Uyghur medicinal material Ocimum basilicum L. seeds and evaluation of its in vitro antioxidant activity
Published on
Frontiers in Pharmaceutical Sciences
2026,30(4):624-631.
932 times
233 times
WANG Lei
WANG Fanhong
CHEN Mo
LI Zhen
Ocimum basilicum L. seeds
Total polyphenols
Ultrasonic-assisted extraction
Orthogonal experiment
Single-factor test
DPPH
ABTS
Antioxidant activity
Details
Study on differences in inorganic element contents between raw and processed Rubia cordifolia
Published on
Frontiers in Pharmaceutical Sciences
2026,30(4):632-638.
844 times
209 times
ZHAO Duanwei
ZHANG Mingtong
LIU Zhirong
Rubia cordifolia
Processed products
Multivariate statistical analysis
Inorganic elements
Hierarchical clustering analysis
Principal component analysis
Orthogonal partial least squares-discriminant analysis
Inductively coupled plasma mass spectrometry
Details
Visualization analysis on research progress and trends of Radix Bupleuri
Published on
Frontiers in Pharmaceutical Sciences
2026,30(4):639-648.
981 times
202 times
ZHANG Xiuna
FANG Jing
TIAN Hui
ZHAO Chaoyue
YANG Yidi
QU Fanna
Chinese medicinal materials
Radix Bupleuri
Bibliometrics
Visualization analysis
CiteSpace
Network pharmacology
Quality control
Details
Adverse event signal mining and analysis of tucatinib based on the FAERS database
Published on
Frontiers in Pharmaceutical Sciences
2026,30(4):649-656.
851 times
188 times
ZHAO Jun
ZHAO Zhenying
WANG Meisa
LI Weiya
JIANG Yuan
YANG Fengkun
Tucatinib
Breast cancer
HER2 inhibitor
FAERS database
Adverse event
Disproportionality method
Details
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