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A total of 2533 result was found. Results

Protection mechanism of myocardial tissues of Wnt/β-catenin signaling inhibition by GAS5 in rats with coronary artery disease

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):739-746.
11537 times 1857 times

WANG Qunye LI Chunhong XU Lu

Growth arrest-specific 5 Wnt/β-catenin signaling pathway Coronary heart disease Myocardial injury Myocardial enzymes Apoptosis
Details
Optimization of the matrix formulation of Shangjin Zhitong gel patch by Box-Behnken response surface methodology

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):747-755.
11651 times 1947 times

LONG Zechun LIU Yang SHI Qiongzhi LIU Hui XIONG Chengjie HU Hua

Shangjin Zhitong gel Gel patch Formulation optimization Box-Behnken response surface methodology
Details
Feasibility study on mercury-free green testing of hydrochloride salt drugs in the Chinese Pharmacopoeia

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):756-763.
10647 times 1993 times

LIU Huiying LI Shangying HUANG Hai XU Wankui

Hydrochloride drugs Method substitution Mercury salt elimination Green drug testing Quality control
Details
Effect of GnRH antagonist combined with rLH on IVF outcomes in patients with low LH levels

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):764-771.
9735 times 1771 times

CHEN Mei YANG Lihua WANG Rong

Gonadotropin-releasing hormone antagonist Recombinant luteinizing hormone Low luteinizing hormone Ovarian responsiveness In vitro fertilization pregnancy
Details
The clinical efficacy of piperacillin-tazobactam sodium combined with budesonide in the treatment of patients with AECOPD

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):772-778.
10937 times 1825 times

WANG Xiaofang WU Yueming PAN Liuhua

Piperacillin-tazobactam sodium Budesonide Acute exacerbation of chronic obstructive pulmonary disease Inflammatory factors
Details
Comparison of the efficacy of different fluid resuscitation regimens on traumatic hemorrhagic shock

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):779-786.
10198 times 1790 times

HE Mengxi PAN Aidi CHEN Linglong YE Ru

Fluid resuscitation Therapeutic hypothermia Traumatic hemorrhagic shock
Details
Analysis of influencing factors and construction of risk prediction model for adverse bleeding reactions in patients with acute cerebral infarction treated with alteplase

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):787-793.
10282 times 1845 times

LIN Qiao YANG Jingying ZHOU Yayan ZHOU Weibin MA Xiaotong

Acute cerebral infarction Alteplase Thrombolysis Bleeding Risk factors Risk prediction model
Details
Placebo effect in children with acute upper respiratory infection: a systematic review and Meta-analysis

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):794-801.
11781 times 1992 times

YANG Jinyu NIU Liqing CAI Qiuhan XU Yaqian CHEN Lulu HU Siyuan

Children Upper respiratory infection Placebo effect Systematic review Meta-analysis
Details
Exploration of the pharmacological activities and medicinal values of different parts of Sea buckthorn

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):802-815.
16398 times 2686 times

LIU Qiuyue ZHANG Zhendong LIU Shumin LU Fang

Sea buckthorn fruit Sea buckthorn leaves Sea buckthorn seeds Pharmacological effects Development and utilization
Details
Research progress on toxicological evaluation and pharmacological effects of Sweet potato (Ipomaea batatas L.) leaves

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):816-831.
14521 times 2156 times

LYU Haihua HUANG Chenchen TANG Qiuyan LIANG Sen QIN Linfeng FENG Junzhou GAO Xingxin

Sweet potato leaves Toxicological evaluation Pharmacological effects Research progress Development and utilization
Details
Research progress on the hepatoprotective mechanism of Berberis and its active components

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):832-848.
11091 times 2199 times

YANG Guibin GUI Mingan GUO Hao ZHUOMA Dongzhi YUAN Ruiying

Berberis Active ingredient Liver disease Hepatoprotective effect
Details
Research progress on the structural modification and anti-lung cancer activity of natural product erianin

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):849-858.
11626 times 1853 times

LIU Jing ZHANG Na LI Xiaolu ZHAO Bin

Erianin Structural modification Anti-lung cancer Molecular mechanisms Research progress
Details
Research of progress medicinal components and quality control of Sambucus L. plants

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):859-867.
12276 times 2444 times

YANG Liu ZHAO Chenxi CHEN Anxin WANG Dongna WANG Meihua LI Tingting

Sambucus L. Application Chemical constituents Pharmacological effects Quality standard
Details
Research progress on decolorization methods of saponins

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):868-876.
14275 times 2100 times

LIAO Binbin ZHANG Jianying ZHANG Xinjian WANG Hongyun CAI Qunhu ZUO Aixue

Saponins Extraction Decolorization method Oxidative decolorization Reduction decolorization Adsorption decolorization Process decolorization Research progress
Details
Research progress of antibody-drug conjugates and analysis of their current application status in gastric cancer patients

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):877-886.
10156 times 1901 times

ZHU Wenbing GUO Chao DAI Yujie QIN Yue ZHOU Jiangping ZHU Wenjing

Antibody-drug conjugates Targeted therapy Gastric cancer patients Research progress Application Status
Details