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A total of 1727 result was found. Results

The effect of butylphthalein regulating the PI3K/Akt/CREB signaling pathway on cisplatin-induced inflammation and apoptosis in PC12 cells

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):721-729.
2031 times 333 times

YAO Mengyuan WEN Min HUANG Zhengyuan CHEN Peng ZHOU Benhong

Butylphthalide Neuroprotection Apoptosis Chemotherapy-related cognitive impairment PC12 cells
Details
Mechanism of Xianju Xiaozhen decoction in treating atopic dermatitis based on network pharmacology and molecular docking

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):730-738.
2126 times 334 times

CHEN Wendong ZHOU Chao XU Xinchang FENG Shuhang GUAN Jiaqi WANG Lei ZHA Weifeng

Xianju Xiaozhen decoction Atopic dermatitis Molecular mechanism Network pharmacology Molecular docking
Details
Protection mechanism of myocardial tissues of Wnt/β-catenin signaling inhibition by GAS5 in rats with coronary artery disease

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):739-746.
2098 times 310 times

WANG Qunye LI Chunhong XU Lu

Growth arrest-specific 5 Wnt/β-catenin signaling pathway Coronary heart disease Myocardial injury Myocardial enzymes Apoptosis
Details
Optimization of the matrix formulation of Shangjin Zhitong gel patch by Box-Behnken response surface methodology

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):747-755.
1967 times 297 times

LONG Zechun LIU Yang SHI Qiongzhi LIU Hui XIONG Chengjie HU Hua

Shangjin Zhitong gel Gel patch Formulation optimization Box-Behnken response surface methodology
Details
Feasibility study on mercury-free green testing of hydrochloride salt drugs in the Chinese Pharmacopoeia

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):756-763.
2051 times 321 times

LIU Huiying LI Shangying HUANG Hai XU Wankui

Hydrochloride drugs Method substitution Mercury salt elimination Green drug testing Quality control
Details
Effect of GnRH antagonist combined with rLH on IVF outcomes in patients with low LH levels

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):764-771.
2074 times 286 times

CHEN Mei YANG Lihua WANG Rong

Gonadotropin-releasing hormone antagonist Recombinant luteinizing hormone Low luteinizing hormone Ovarian responsiveness In vitro fertilization pregnancy
Details
The clinical efficacy of piperacillin-tazobactam sodium combined with budesonide in the treatment of patients with AECOPD

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):772-778.
2136 times 290 times

WANG Xiaofang WU Yueming PAN Liuhua

Piperacillin-tazobactam sodium Budesonide Acute exacerbation of chronic obstructive pulmonary disease Inflammatory factors
Details
Comparison of the efficacy of different fluid resuscitation regimens on traumatic hemorrhagic shock

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):779-786.
2160 times 306 times

HE Mengxi PAN Aidi CHEN Linglong YE Ru

Fluid resuscitation Therapeutic hypothermia Traumatic hemorrhagic shock
Details
Analysis of influencing factors and construction of risk prediction model for adverse bleeding reactions in patients with acute cerebral infarction treated with alteplase

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):787-793.
2067 times 291 times

LIN Qiao YANG Jingying ZHOU Yayan ZHOU Weibin MA Xiaotong

Acute cerebral infarction Alteplase Thrombolysis Bleeding Risk factors Risk prediction model
Details
Placebo effect in children with acute upper respiratory infection: a systematic review and Meta-analysis

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):794-801.
2113 times 321 times

YANG Jinyu NIU Liqing CAI Qiuhan XU Yaqian CHEN Lulu HU Siyuan

Children Upper respiratory infection Placebo effect Systematic review Meta-analysis
Details
Exploration of the pharmacological activities and medicinal values of different parts of Sea buckthorn

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):802-815.
2552 times 384 times

LIU Qiuyue ZHANG Zhendong LIU Shumin LU Fang

Sea buckthorn fruit Sea buckthorn leaves Sea buckthorn seeds Pharmacological effects Development and utilization
Details
Research progress on toxicological evaluation and pharmacological effects of Sweet potato (Ipomaea batatas L.) leaves

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):816-831.
2352 times 313 times

LYU Haihua HUANG Chenchen TANG Qiuyan LIANG Sen QIN Linfeng FENG Junzhou GAO Xingxin

Sweet potato leaves Toxicological evaluation Pharmacological effects Research progress Development and utilization
Details
Research progress on the hepatoprotective mechanism of Berberis and its active components

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):832-848.
2265 times 365 times

YANG Guibin GUI Mingan GUO Hao ZHUOMA Dongzhi YUAN Ruiying

Berberis Active ingredient Liver disease Hepatoprotective effect
Details
Research progress on the structural modification and anti-lung cancer activity of natural product erianin

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):849-858.
2068 times 283 times

LIU Jing ZHANG Na LI Xiaolu ZHAO Bin

Erianin Structural modification Anti-lung cancer Molecular mechanisms Research progress
Details
Research of progress medicinal components and quality control of Sambucus L. plants

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):859-867.
2369 times 355 times

YANG Liu ZHAO Chenxi CHEN Anxin WANG Dongna WANG Meihua LI Tingting

Sambucus L. Application Chemical constituents Pharmacological effects Quality standard
Details