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A total of 51 result was found. Results that relate to Target

Identification of potential drug targets for restless legs syndrome by Mendelian randomization analysis based on plasma proteomics

Published on New Medicine 2025,35(10):1181-1187.
6937 times 1343 times

ZHANG Qinli XU Hua HAN Xiuyan LIU Hong

Restless legs syndrome Mendelian randomization Drug targets Plasma proteomics
Details
Research advances in adverse drug reactions and their management in targeted therapy for driver gene-positive advanced non-small cell lung cancer

Published on Chinese Journal of Pharmacoepidemiology 2025,34(11):1320-1329.
8638 times 1366 times

FAN Jiameng PAN Lei

Non-small cell lung cancer Target therapy Adverse drug reactions Symptom management Biomarker
Details
Application and research progress of nanomaterials in ischemic stroke therapy

Published on New Medicine 2025,35(11):1355-1360.
6741 times 1237 times

LI Zhuoyuan PENG Zheng ZHU Xiaolong LI Wei HANG Chunhua

Ischemic stroke Nanomaterials Targeted therapy
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Exploring the anti-uterine fibroids mechanism of Rubia yunnanensis based on network pharmacology and molecular docking technology

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1801-1810.
7226 times 1290 times

WANG Hong LI Yanhua

Rubia yunnanensis Uterine fibroids Network pharmacology Molecular docking type Action mechanism Target Protein-protein interaction Signaling pathways
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Research progress on the chemical constituents and pharmacological effects of Chinese yam

Published on Frontiers in Pharmaceutical Sciences 2025,29(12):2098-2111.
8808 times 1443 times

ZHENG Xiaonan SUN Cuige DI Qing HU Liping ZHAO Xiangxuan

Chinese yam Chemical composition Pharmacological effects Chronic atrophic gastritis Drug target Network pharmacology Targeted drugs Natural products
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Exploring the in vitro anti-tumor effect and mechanism of Rumex chalepensis based on network pharmacology

Published on Frontiers in Pharmaceutical Sciences 2026,30(1):2-11.
3578 times 779 times

GUO Changhong YAN Guangjun MIAO Qing LIU Limei XU Jing LIU Chong WANG Yejing XIANG Caiqiong

Rumex chalepensis Network pharmacology Gastric cancer PI3K/Akt signaling pathway Apoptosis Cell cycle arrest Multi-target action Natural anti-tumor drug
Details
Guide on Methodological Standards in Pharmacoepidemiology (2nd edition) and their series interpretation (14): research designs and case studies of target trial emulation

Published on Chinese Journal of Pharmacoepidemiology 2026,35(2):121-132.
6722 times 1398 times

ZHAO Houyu CHENG Yinchu SUN Feng ZHAN Siyan

Target trial emulation Pharmacoepidemiology Methodology Guidelines Active comparator new-user design Sequential trial Clone-censor-weight
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Research progress on TGF-β pathway inhibitors for treating hepatic fibrosis

Published on Frontiers in Pharmaceutical Sciences 2026,30(2):347-360.
4494 times 789 times

WU Yalin TIAN Sha

Hepatic fibrosis TGF-β signaling pathway Hepatic stellate cells Inhibitors Therapeutic target Molecular mechanisms Drug delivery systems Traditional Chinese medicine compounds
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Effect of regular consumption of "medicine and food homology" traditional Chinese medicine on activities of daily living in the elderly: a target trial emulation

Published on New Medicine 2026,36(3):259-267.
3864 times 1046 times

WANG Zhaoyu LIAO Jiaojiao LI Zhaoji WANG Hui TAO Liyuan

Medicine and food homology Traditional Chinese medicine Activities of daily living Target trial emulation Cohort study
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Integrating network pharmacology and molecular docking to elucidate the therapeutic mechanisms of Foeniculum vulgare against hepatocellular carcinoma

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):361-370.
5239 times 841 times

DENG Xiaying ZHAO Xiangxuan

Foeniculum vulgare Network pharmacology Network targets Hepatocellular carcinoma Mechanism of action Molecular docking Targeted therapy Natural products
Details
Analysis of the safety profile of zavegepant based on the FAERS database and comparison with CGRP-targeted drugs

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):455-465.
4161 times 800 times

XIE Jinlian WANG Qing ZHANG Xingfei ZHANG Yaxin WU Qian MA Junlong KUANG Yun GUO Chengxian

Calcitonin gene-related peptide-targeted medication Zavegepant FAERS database Signal mining Disproportionality analysis Bayesian confidence propagation neural network Adverse events Pharmacovigilance
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Research progress on the function of FKBP5 and its role in neuropsychiatric disorders

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):502-511.
4088 times 901 times

XING Jiaxin ZHAO Mingyi SONG Rui LI Hong

FK506 binding protein 5 Neuropsychiatric disorders Protein structure Molecular function Expression regulation Therapeutic target Drug research Clinical application prospects
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Recent advances of non-viral vectors in DNA drug delivery field

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):520-529.
4310 times 866 times

LIU Hanxiao YANG Xuehua LIU Zhengping MAO Kaifan XUE Song LI Dawei TANG Xuan

Non-viral vectors DNA drugs Delivery systems Targeted delivery Nanocarriers Biocompatibility Gene therapy Clinical translation
Details
Research advances in targeted protein degradation technologies

Published on New Medicine 2026,36(4):464-470.
3217 times 804 times

PI Chuan HAO Xuanrun XIAO Haiting LUO Xing ZHANG Qixiong

Targeted protein degradation Proteolysis targeting chimera Molecular glue Lysosome-targeting chimera Autophagy-targeting chimera Autophagosome-tethering compound
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Mechanism of Gualou Xiebai decoction in treating myocardial infarction based on UPLC-Orbitrap-MS/MS and network pharmacology

Published on Frontiers in Pharmaceutical Sciences 2026,30(4):555-565.
3048 times 778 times

YAN Muxian LAN Yikun ZHOU Yaliang TAN Wanchuang LIN Junjie

Gualou Xiebai decoction Myocardial infarction Network pharmacology Ul-tra-performance liquid chromatography-orbitrap tandem mass spectrometry Mechanism of action Active components Target prediction
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