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A total of 35 result was found. Results that relate to Signaling pathway

Research progress on quercetin and organ ischemia/reperfusion injury

Published on Frontiers in Pharmaceutical Sciences 2025,29(3):506-515.
7747 times 1670 times

DONG Jingyu WANG Wenbo LIU Yang LI Na

Quercetin Ischemia/reperfusion injury Research progress Signaling pathways
Details
Research progress on the role of vitamin D and its signaling pathway in disease development

Published on Chinese Journal of Pharmacoepidemiology 2025,34(4):456-466.
15749 times 4511 times

ZHANG Xiaomei YE Hui YANG Fang MIN Rui TONG Yeqing

Vitamin D Signaling pathways Occurrence of disease
Details
Protection mechanism of myocardial tissues of Wnt/β-catenin signaling inhibition by GAS5 in rats with coronary artery disease

Published on Frontiers in Pharmaceutical Sciences 2025,29(5):739-746.
8549 times 1173 times

WANG Qunye LI Chunhong XU Lu

Growth arrest-specific 5 Wnt/β-catenin signaling pathway Coronary heart disease Myocardial injury Myocardial enzymes Apoptosis
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Research progress on mTOR signaling pathway in depression

Published on Journal of Mathematical Medicine 2025,38(8):620-628.
6186 times 1360 times

LIU Xinyu WANG Zhijian SHEN Zhongfei GUO Yanjun

mTOR signaling pathway Depression Neuroinflammation Synaptic plasticity
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Mechanism of isoliquiritigenin in the treatment of oral submucous fibrosis based on network pharmacology and experimental validation

Published on Journal of Mathematical Medicine 2025,38(9):665-677.
5785 times 1109 times

LIU Gen GUO Sheng PENG Jiamei LI Yijie LU Ruqing

Isoliquiritigenin Oral submucous fibrosis Network pharmacology Molecular docking Signaling pathway Cell experiment
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Research progress on the mechanism of physiological and pathological cardiac hypertrophy and the intervention of traditional Chinese medicine

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1954-1964.
5284 times 763 times

ZHOU Shiguo HE Wenjie CHEN Pingping LU Fang

Cardiac hypertrophy Physiological and pathological Molecular regulation mechanism Signaling pathway Chinese medicine intervention mTOR PGC-1α miRNA
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Research status of active ingredients in traditional Chinese medicine on the regulation of Notch signaling pathway in the treatment of prostate cancer

Published on Journal of Mathematical Medicine 2025,38(10):780-786.
5173 times 984 times

LI Shenglong LI Hui LIANG Yonglin GONG Meisheng ZHAO Yongqiang ZHOU Jiuyun ZHANG Qingwei

Prostate cancer Notch Signaling pathway Active ingredients of traditional Chinese medicine
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Exploring the anti-uterine fibroids mechanism of Rubia yunnanensis based on network pharmacology and molecular docking technology

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1801-1810.
4696 times 766 times

WANG Hong LI Yanhua

Rubia yunnanensis Uterine fibroids Network pharmacology Molecular docking type Action mechanism Target Protein-protein interaction Signaling pathways
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Exploring the potential mechanism of Codonopsis pilosula in treating myocardial injury based on network pharmacology and molecular docking

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1811-1820.
5156 times 836 times

ZHENG Huanqin SHI Xiaodong SHI Wenyin CHENG Shuai

Codonopsis pilosula Myocardial injury Network pharmacology Molecular docking Protein-protein interaction Signaling pathways Inflammation Apoptosis Metabolic homeostasis
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The action mechanism of Shaoyao decoction in the treatment of knee osteoarthritis based on network pharmacology and Mendelian randomization

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1821-1829.
5003 times 746 times

SONG Yang XU Fei LIU Hansen ZHANG Houjian

Shaoyao decoction Knee osteoarthritis Network pharmacology Mendelian randomization Protein-protein interaction Genome-wide association studies Single nucleotide polymorphisms Signaling pathway
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Integrated network pharmacology and molecular docking to explore the potential molecular mechanisms of diosmin against prostatic hyperplasia complicated with chronic prostatitis

Published on Frontiers in Pharmaceutical Sciences 2025,29(12):1981-1989.
3050 times 643 times

TANG Liu JIANG Xiao LUO Guangwen WANG Lei

Diosmin Benign prostatic hyperplasia Chronic prostatitis Network pharmacology Molecular docking Signaling pathway GO funnction analysis KEGG pathway analysis
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Exploring the effect of astragalus polysaccharides on adriamycin-induced apoptosis of AC16 cardiomyocytes based on the TGF-β1/Smad3 signaling pathway

Published on Frontiers in Pharmaceutical Sciences 2025,29(12):2009-2016.
2596 times 548 times

WANG Dui DANG Lijuan ZHANG Qiang ZHAO Xiaobin LI Xiaoyu ZHANG Zhengfeng

Astragalus polysaccharides Doxorubicin Myocardial injury TGF-β1/Smad3 signaling pathway Traditional Chinese medicine AC16 Cardiomyocytes Apoptosis
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Research progress in the treatment of simple obesity with traditional Chinese medicine compounds

Published on Frontiers in Pharmaceutical Sciences 2025,29(12):2137-2144.
4049 times 603 times

ZHANG Xiali WANG Zhuo MI Li

Simple obesity Traditional Chinese medicine compounding Research progress Leptin resistance Insulin resistance Gut microbiota dysbiosis JAK2-STAT3 signaling pathway PI3K/Akt signaling pathway
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Exploring the in vitro anti-tumor effect and mechanism of Rumex chalepensis based on network pharmacology

Published on Frontiers in Pharmaceutical Sciences 2026,30(1):2-11.
2198 times 476 times

GUO Changhong YAN Guangjun MIAO Qing LIU Limei XU Jing LIU Chong WANG Yejing XIANG Caiqiong

Rumex chalepensis Network pharmacology Gastric cancer PI3K/Akt signaling pathway Apoptosis Cell cycle arrest Multi-target action Natural anti-tumor drug
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Network pharmacological exploration of the mechanism of Scutellaria baicalensis antigenic primary biliary cholangitis

Published on Frontiers in Pharmaceutical Sciences 2026,30(2):181-189.
2039 times 404 times

WANG Chunxia ZHAO Zan GUO Qinghong

Primary biliary cholangitis Scutellaria baicalensis Network pharmacology Molecular docking Molecular dynamics simulation Signaling pathways GO function analysis KEGG pathway enrichment analysis
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