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A total of 44 result was found. Results that relate to Signaling

Exploring the in vitro anti-tumor effect and mechanism of Rumex chalepensis based on network pharmacology

Published on Frontiers in Pharmaceutical Sciences 2026,30(1):2-11.
4400 times 1138 times

GUO Changhong YAN Guangjun MIAO Qing LIU Limei XU Jing LIU Chong WANG Yejing XIANG Caiqiong

Rumex chalepensis Network pharmacology Gastric cancer PI3K/Akt signaling pathway Apoptosis Cell cycle arrest Multi-target action Natural anti-tumor drug
Details
Network pharmacological exploration of the mechanism of Scutellaria baicalensis antigenic primary biliary cholangitis

Published on Frontiers in Pharmaceutical Sciences 2026,30(2):181-189.
4969 times 1158 times

WANG Chunxia ZHAO Zan GUO Qinghong

Primary biliary cholangitis Scutellaria baicalensis Network pharmacology Molecular docking Molecular dynamics simulation Signaling pathways GO function analysis KEGG pathway enrichment analysis
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Exploring the mechanism of action of Aconitum Heterophyllum in treating gout based on network pharmacology and molecular modeling

Published on Frontiers in Pharmaceutical Sciences 2026,30(2):190-200.
4906 times 1028 times

ZHANG Ruirui CHEN Quansheng ZHANG Bingyin WU Yuwen YAN Caifeng

Aconitum Heterophyllum Gout Network pharmacology Molecular docking Molecular dynamics simulation Active ingredients Signaling pathways Protein-protein interactions
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Research progress on TGF-β pathway inhibitors for treating hepatic fibrosis

Published on Frontiers in Pharmaceutical Sciences 2026,30(2):347-360.
5763 times 1158 times

WU Yalin TIAN Sha

Hepatic fibrosis TGF-β signaling pathway Hepatic stellate cells Inhibitors Therapeutic target Molecular mechanisms Drug delivery systems Traditional Chinese medicine compounds
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The mechanism of Cistanche phenylethanol glycosides in inhibiting tumor growth in nude mice bearing drug-resistant osteosarcoma

Published on Journal of Mathematical Medicine 2026,39(2):92-100.
4384 times 1191 times

DING Juxian XIE Xingwen LI Dingpeng LI Ning XU Wei WANG Kai FANG Yan XU Shihong WANG Xiaoqiang LI Jianguo SU Jiliang

Osteosarcoma Cistanche phenylethanol glycosides MG-63 Tumor cells Apoptosis Mechanism PI3K/AKT/mTOR signaling pathway
Details
Exploring the mechanism of astragaloside IV in the treatment of ischemic stroke based on integrated pharmacology

Published on Journal of Mathematical Medicine 2026,39(2):101-113.
4935 times 1233 times

LI Bo XU Hao HUANG Xiuxiu HOU Fen ZOU Ziqin LI Qun

Ischemic stroke Astragaloside IV Network pharmacology Molecular docking TNF/NF-κB signaling pathway
Details
Role and mechanism of RGS14 in improving acute myocardial infarction by inhibiting TAK1 activation

Published on New Medicine 2026,36(2):169-178.
4816 times 1279 times

WU Qinghua DUAN Shaofeng TAN Chongyuan ZHANG Lirong ZHANG Jiaxing HU Yufeng SHE Zhigang LI Hongliang

Regulator of G-protein signaling 14 Acute myocardial infarction Inflammation Apoptosis TAK1
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Research progress of traditional Chinese medicine on the regulation of Notch signaling pathway in the treatment of rheumatoid arthritis

Published on Journal of Mathematical Medicine 2026,39(4):294-300.
5900 times 1168 times

LI Mingxia CHEN Junlong HE Bianqiang HE Wenkui GAO Wanpeng

Rheumatoid arthritis Notch signaling pathway Traditional Chinese medicine Mechanism
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Research progress on the treatment of sarcopenia by traditional Chinese medicine regulating the PI3K/Akt/mTOR signaling pathway

Published on Chinese Journal of Pharmacoepidemiology 2026,35(6):689-699.
3676 times 888 times

ZHAO Rongcan ZHAO Liang

Sarcopenia PI3K/Akt/mTOR signaling pathway Traditional Chinese medicine monomer Traditional Chinese medicine compound Mechanism of action
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Study on the effect and mechanism of Polygoni Orientalis Fructus on nonalcoholic fatty liver disease based on network pharmacology and experimental validation

Published on Frontiers in Pharmaceutical Sciences 2026,30(6):901-909.
3143 times 873 times

GAO Shuchang HAN Danrui MA Donglai WANG Xiaona DUAN Xuhong

Polygoni Orientalis Fructus NAFLD Network pharmacology Molecular docking Signaling pathway Mechanism of action Zebrafish model Lipid metabolism
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The mechanism of silybin in treating against gastric cancer based on systematic network pharmacology analysis

Published on Journal of Mathematical Medicine 2026,39(6):445-453.
2217 times 751 times

MI Jiali SHI Lei WANG Lina WU Chaocai

Silybin Gastric cancer Network pharmacology PI3K/AKT signaling pathway Cell proliferation Cell migration Mechanism
Details
Mechanism study of glycyrrhizin in the treatment of oral squamous cell carcinoma based on network pharmacology and in vitro cell experiments

Published on Frontiers in Pharmaceutical Sciences 2026,30(7):1081-1091.
2237 times 705 times

TIAN Zhongjia LEI Yintao LI Junfu WANG Qian

Glycyrrhizin Oral squamous cell carcinoma Network pharmacology Molecular docking Notch signaling pathway
Details
Study on the action mechanism of Herba Verbenae-Campsis Flos herb pair in treating thyroid nodules based on network pharmacology and molecular docking

Published on Frontiers in Pharmaceutical Sciences 2026,30(9):1457-1468.
764 times 224 times

LI Chang GAO Shuchang HAN Danrui DUAN Xuhong

Thyroid nodules Herba Verbenae-Campsis Flos herb pair Network pharmacology Molecular docking Signaling pathway Mechanism of action
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Exploration of the potential mechanism of Zhuling decoction in the intervention of diabetic kidney disease based on network pharmacology, molecular docking and molecular dynamics simulation

Published on Frontiers in Pharmaceutical Sciences 2026,30(9):1469-1483.
713 times 197 times

CHEN Jiaqi WU Binxin LING Kai'en

Zhuling decoction Diabetic kidney disease Network pharmacology PI3K-Akt signaling pathway
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