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Wuhan University
Zhongnan Hospital of Wuhan University
Center for Evidence-Based and Translational Medicine of Wuhan University
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A total of
37
result was found. Results that relate to
Signaling
Exploring the in vitro anti-tumor effect and mechanism of Rumex chalepensis based on network pharmacology
Published on
Frontiers in Pharmaceutical Sciences
2026,30(1):2-11.
1543 times
342 times
GUO Changhong
YAN Guangjun
MIAO Qing
LIU Limei
XU Jing
LIU Chong
WANG Yejing
XIANG Caiqiong
Rumex chalepensis
Network pharmacology
Gastric cancer
PI3K/Akt
signaling
pathway
Apoptosis
Cell cycle arrest
Multi-target action
Natural anti-tumor drug
Details
Network pharmacological exploration of the mechanism of Scutellaria baicalensis antigenic primary biliary cholangitis
Published on
Frontiers in Pharmaceutical Sciences
2026,30(2):181-189.
1239 times
282 times
WANG Chunxia
ZHAO Zan
GUO Qinghong
Primary biliary cholangitis
Scutellaria baicalensis
Network pharmacology
Molecular docking
Molecular dynamics simulation
Signaling
pathways
GO function analysis
KEGG pathway enrichment analysis
Details
Exploring the mechanism of action of Aconitum Heterophyllum in treating gout based on network pharmacology and molecular modeling
Published on
Frontiers in Pharmaceutical Sciences
2026,30(2):190-200.
1270 times
258 times
ZHANG Ruirui
CHEN Quansheng
ZHANG Bingyin
WU Yuwen
YAN Caifeng
Aconitum Heterophyllum
Gout
Network pharmacology
Molecular docking
Molecular dynamics simulation
Active ingredients
Signaling
pathways
Protein-protein interactions
Details
Research progress on TGF-β pathway inhibitors for treating hepatic fibrosis
Published on
Frontiers in Pharmaceutical Sciences
2026,30(2):347-360.
1172 times
192 times
WU Yalin
TIAN Sha
Hepatic fibrosis
TGF-β
signaling
pathway
Hepatic stellate cells
Inhibitors
Therapeutic target
Molecular mechanisms
Drug delivery systems
Traditional Chinese medicine compounds
Details
The mechanism of Cistanche phenylethanol glycosides in inhibiting tumor growth in nude mice bearing drug-resistant osteosarcoma
Published on
Journal of Mathematical Medicine
2026,39(2):92-100.
1140 times
315 times
DING Juxian
XIE Xingwen
LI Dingpeng
LI Ning
XU Wei
WANG Kai
FANG Yan
XU Shihong
WANG Xiaoqiang
LI Jianguo
SU Jiliang
Osteosarcoma
Cistanche phenylethanol glycosides
MG-63
Tumor cells
Apoptosis
Mechanism
PI3K/AKT/mTOR
signaling
pathway
Details
Exploring the mechanism of astragaloside IV in the treatment of ischemic stroke based on integrated pharmacology
Published on
Journal of Mathematical Medicine
2026,39(2):101-113.
1329 times
355 times
LI Bo
XU Hao
HUANG Xiuxiu
HOU Fen
ZOU Ziqin
LI Qun
Ischemic stroke
Astragaloside IV
Network pharmacology
Molecular docking
TNF/NF-κB
signaling
pathway
Details
Role and mechanism of RGS14 in improving acute myocardial infarction by inhibiting TAK1 activation
Published on
New Medicine
2026,36(2):169-178.
1746 times
297 times
WU Qinghua
DUAN Shaofeng
TAN Chongyuan
ZHANG Lirong
ZHANG Jiaxing
HU Yufeng
SHE Zhigang
LI Hongliang
Regulator of G-protein
signaling
14
Acute myocardial infarction
Inflammation
Apoptosis
TAK1
Details
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