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A total of 92 result was found. Results that relate to Signal

Research progress on TGF-β pathway inhibitors for treating hepatic fibrosis

Published on Frontiers in Pharmaceutical Sciences 2026,30(2):347-360.
4495 times 789 times

WU Yalin TIAN Sha

Hepatic fibrosis TGF-β signaling pathway Hepatic stellate cells Inhibitors Therapeutic target Molecular mechanisms Drug delivery systems Traditional Chinese medicine compounds
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The mechanism of Cistanche phenylethanol glycosides in inhibiting tumor growth in nude mice bearing drug-resistant osteosarcoma

Published on Journal of Mathematical Medicine 2026,39(2):92-100.
3518 times 925 times

DING Juxian XIE Xingwen LI Dingpeng LI Ning XU Wei WANG Kai FANG Yan XU Shihong WANG Xiaoqiang LI Jianguo SU Jiliang

Osteosarcoma Cistanche phenylethanol glycosides MG-63 Tumor cells Apoptosis Mechanism PI3K/AKT/mTOR signaling pathway
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Exploring the mechanism of astragaloside IV in the treatment of ischemic stroke based on integrated pharmacology

Published on Journal of Mathematical Medicine 2026,39(2):101-113.
3965 times 995 times

LI Bo XU Hao HUANG Xiuxiu HOU Fen ZOU Ziqin LI Qun

Ischemic stroke Astragaloside IV Network pharmacology Molecular docking TNF/NF-κB signaling pathway
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Role and mechanism of RGS14 in improving acute myocardial infarction by inhibiting TAK1 activation

Published on New Medicine 2026,36(2):169-178.
3917 times 1010 times

WU Qinghua DUAN Shaofeng TAN Chongyuan ZHANG Lirong ZHANG Jiaxing HU Yufeng SHE Zhigang LI Hongliang

Regulator of G-protein signaling 14 Acute myocardial infarction Inflammation Apoptosis TAK1
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Analysis of the safety profile of zavegepant based on the FAERS database and comparison with CGRP-targeted drugs

Published on Frontiers in Pharmaceutical Sciences 2026,30(3):455-465.
4161 times 800 times

XIE Jinlian WANG Qing ZHANG Xingfei ZHANG Yaxin WU Qian MA Junlong KUANG Yun GUO Chengxian

Calcitonin gene-related peptide-targeted medication Zavegepant FAERS database Signal mining Disproportionality analysis Bayesian confidence propagation neural network Adverse events Pharmacovigilance
Details
Signal mining and analysis of lanadelumab-associated adverse events based on the FAERS database

Published on Chinese Journal of Pharmacoepidemiology 2026,35(5):535-541.
2803 times 660 times

WU Jiayu SU Rui REN Quanwei GONG Jiannan

Lanadelumab FAERS database Adverse adverse events Hereditary angioedema Signal mining Pharmacovigilance
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Signal mining and analysis of adverse events associated with the use of beta-1 blockers in children based on the FAERS database

Published on Chinese Journal of Pharmacoepidemiology 2026,35(5):542-552.
2083 times 571 times

CHANG Qiuyue SHANG Shenglan ZHAO Yan YU Mengchen YU Airong

Metoprolol Bisoprolol Atenolol Esmolol Adverse drug events Signal mining Pharmacovigilance
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Research progress of traditional Chinese medicine on the regulation of Notch signaling pathway in the treatment of rheumatoid arthritis

Published on Journal of Mathematical Medicine 2026,39(4):294-300.
4064 times 844 times

LI Mingxia CHEN Junlong HE Bianqiang HE Wenkui GAO Wanpeng

Rheumatoid arthritis Notch signaling pathway Traditional Chinese medicine Mechanism
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Research progress on the treatment of sarcopenia by traditional Chinese medicine regulating the PI3K/Akt/mTOR signaling pathway

Published on Chinese Journal of Pharmacoepidemiology 2026,35(6):689-699.
2301 times 451 times

ZHAO Rongcan ZHAO Liang

Sarcopenia PI3K/Akt/mTOR signaling pathway Traditional Chinese medicine monomer Traditional Chinese medicine compound Mechanism of action
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Study on the effect and mechanism of Polygoni Orientalis Fructus on nonalcoholic fatty liver disease based on network pharmacology and experimental validation

Published on Frontiers in Pharmaceutical Sciences 2026,30(6):901-909.
1808 times 434 times

GAO Shuchang HAN Danrui MA Donglai WANG Xiaona DUAN Xuhong

Polygoni Orientalis Fructus NAFLD Network pharmacology Molecular docking Signaling pathway Mechanism of action Zebrafish model Lipid metabolism
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The mechanism of silybin in treating against gastric cancer based on systematic network pharmacology analysis

Published on Journal of Mathematical Medicine 2026,39(6):445-453.
1199 times 396 times

MI Jiali SHI Lei WANG Lina WU Chaocai

Silybin Gastric cancer Network pharmacology PI3K/AKT signaling pathway Cell proliferation Cell migration Mechanism
Details
Mining and analysis of adverse event signals for three novel lipoglycopeptide antibiotics based on the FAERS and WHO-VigiAccess database

Published on Chinese Journal of Pharmacoepidemiology 2026,35(7):773-782.
924 times 318 times

ZHANG Yao HU Zhansong ZHAO Xiaoyun CHEN Lijuan

Lipoglycopeptide antibiotics Adverse events FAERS WHO-VigiAccess Signal mining
Details
Signal mining and analysis of adverse events of mirikizumab based on FAERS and EudraVigilance databases

Published on Chinese Journal of Pharmacoepidemiology 2026,35(7):783-791.
917 times 310 times

YAN Xu SUN Kun JI Zhaoshuai NIE Guangmeng

Mirikizumab Crohn's disease Ulcerative colitis FAERS EudraVigilance Signal mining
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Signal analysis of adverse events associated with pertuzumab-trastuzumab based on the FAERS database

Published on Chinese Journal of Pharmacoepidemiology 2026,35(7):792-799.
976 times 275 times

ZHANG Juan ZHU Haizhou ZHANG Xue GUO Kaixing

Pertuzumab-trastuzumab FAERS database Adverse drug events Signal mining Reporting odds ratio Pharmacovigilance
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Application of R language in pharmacovigilance signal detection

Published on Chinese Journal of Pharmacoepidemiology 2026,35(7):827-835.
973 times 292 times

FU Yali BA Lei ZHOU Jian SHI Wenhui

Pharmacovigilance Signal detection Adverse drug reaction Adverse events R language
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