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A total of 62 result was found. Results that relate to Signal

Signals mining and analysis of adverse drug events of anifrolumab based on FAERS database

Published on Chinese Journal of Pharmacoepidemiology 2025,34(6):650-656.
5568 times 829 times

YAN Fanbin WANG Jia XU Lujie LIU Chang

Anifrolumab Adverse drug events Signal mining Ratio imbalance method Pharmacovigilance
Details
Mining and analysis of thalidomide adverse reaction signals based on FAERS database

Published on Frontiers in Pharmaceutical Sciences 2025,29(6):1025-1032.
5588 times 686 times

YE Dingxun DI Wei

Thalidomide FDA adverse event reporting system database Adverse drug events Signal mining
Details
Research progress on mTOR signaling pathway in depression

Published on Journal of Mathematical Medicine 2025,38(8):620-628.
2375 times 569 times

LIU Xinyu WANG Zhijian SHEN Zhongfei GUO Yanjun

mTOR signaling pathway Depression Neuroinflammation Synaptic plasticity
Details
Mining of adverse reaction signals of amlodipine based on the FAERS database and the construction of a digital and intelligent pharmacovigilance platform

Published on Chinese Journal of Pharmacoepidemiology 2025,34(8):846-854.
2651 times 650 times

HU Yanghui QIU Ziyan ZHANG Bingsong

Amlodipine Adverse drug event Signal mining FAERS database Digital intelligent platform
Details
Effect and mechanism of FOXP1 on the viability and apoptosis of cisplatin resistant cervical cancer cells

Published on New Medicine 2025,35(9):1057-1065.
1745 times 387 times

WANG Xiao DONG Qianjing

FOXP1 Cervical cancer Drug resistance Apoptosis Autophagy Wnt/β-catenin signaling
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A pharmacovigilance study for drug-associated ischaemic stroke based on FAERS database

Published on Frontiers in Pharmaceutical Sciences 2025,29(9):1553-1560.
1996 times 282 times

MA Xiaoling WU Fang GE Weihong YU Feng

Ischaemic stroke Pharmacovigilance Adverse drug events Signal detection Risk of stroke FAERS
Details
Mechanism of isoliquiritigenin in the treatment of oral submucous fibrosis based on network pharmacology and experimental validation

Published on Journal of Mathematical Medicine 2025,38(9):665-677.
2170 times 359 times

LIU Gen GUO Sheng PENG Jiamei LI Yijie LU Ruqing

Isoliquiritigenin Oral submucous fibrosis Network pharmacology Molecular docking Signaling pathway Cell experiment
Details
Signal mining and analysis of gender distribution of adverse events of PCSK9 inhibitors based on the FAERS database

Published on Chinese Journal of Pharmacoepidemiology 2025,34(10):1169-1177.
1399 times 262 times

WANG Lan ZENG Zhujun BIAN Yuan

PCSK9 inhibitor Signal mining Gender distribution Adverse drug events
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Anti-respiratory syncytial virus effect of Dandelion and investigation of mechanism based on network pharmacology

Published on Frontiers in Pharmaceutical Sciences 2025,29(10):1621-1631.
1723 times 297 times

LIU Chunhui CUI Qinghua

Dandelion Respiratory syncytial virus Network pharmacology Epidermal growth factor receptor Signal transducer and activator of transcription 3 Mitogen-activated protein kinase 3 Interleukin 6
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Research progress on the mechanism of physiological and pathological cardiac hypertrophy and the intervention of traditional Chinese medicine

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1954-1964.
1319 times 190 times

ZHOU Shiguo HE Wenjie CHEN Pingping LU Fang

Cardiac hypertrophy Physiological and pathological Molecular regulation mechanism Signaling pathway Chinese medicine intervention mTOR PGC-1α miRNA
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Research status of active ingredients in traditional Chinese medicine on the regulation of Notch signaling pathway in the treatment of prostate cancer

Published on Journal of Mathematical Medicine 2025,38(10):780-786.
1339 times 267 times

LI Shenglong LI Hui LIANG Yonglin GONG Meisheng ZHAO Yongqiang ZHOU Jiuyun ZHANG Qingwei

Prostate cancer Notch Signaling pathway Active ingredients of traditional Chinese medicine
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Exploring the anti-uterine fibroids mechanism of Rubia yunnanensis based on network pharmacology and molecular docking technology

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1801-1810.
643 times 112 times

WANG Hong LI Yanhua

Rubia yunnanensis Uterine fibroids Network pharmacology Molecular docking type Action mechanism Target Protein-protein interaction Signaling pathways
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Exploring the potential mechanism of Codonopsis pilosula in treating myocardial injury based on network pharmacology and molecular docking

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1811-1820.
676 times 103 times

ZHENG Huanqin SHI Xiaodong SHI Wenyin CHENG Shuai

Codonopsis pilosula Myocardial injury Network pharmacology Molecular docking Protein-protein interaction Signaling pathways Inflammation Apoptosis Metabolic homeostasis
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The action mechanism of Shaoyao decoction in the treatment of knee osteoarthritis based on network pharmacology and Mendelian randomization

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1821-1829.
642 times 93 times

SONG Yang XU Fei LIU Hansen ZHANG Houjian

Shaoyao decoction Knee osteoarthritis Network pharmacology Mendelian randomization Protein-protein interaction Genome-wide association studies Single nucleotide polymorphisms Signaling pathway
Details
Analysis of adverse reaction signals of denosumab combined with vitamin D based on the FAERS database

Published on Frontiers in Pharmaceutical Sciences 2025,29(11):1898-1905.
626 times 86 times

SHEN Yang CHEN Jihang

Denosumab Vitamin D FAERS database Adverse drug events Osteoporosis Signal mining Off-label use Benign giant cell tumor of bone Myalgia
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