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A total of 137 result was found. Results that relate to Path

Exploring the effect of astragalus polysaccharides on adriamycin-induced apoptosis of AC16 cardiomyocytes based on the TGF-β1/Smad3 signaling pathway

Published on Frontiers in Pharmaceutical Sciences 2025,29(12):2009-2016.
5036 times 1399 times

WANG Dui DANG Lijuan ZHANG Qiang ZHAO Xiaobin LI Xiaoyu ZHANG Zhengfeng

Astragalus polysaccharides Doxorubicin Myocardial injury TGF-β1/Smad3 signaling pathway Traditional Chinese medicine AC16 Cardiomyocytes Apoptosis
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Research progress in the treatment of simple obesity with traditional Chinese medicine compounds

Published on Frontiers in Pharmaceutical Sciences 2025,29(12):2137-2144.
9382 times 1520 times

ZHANG Xiali WANG Zhuo MI Li

Simple obesity Traditional Chinese medicine compounding Research progress Leptin resistance Insulin resistance Gut microbiota dysbiosis JAK2-STAT3 signaling pathway PI3K/Akt signaling pathway
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Exploring the in vitro anti-tumor effect and mechanism of Rumex chalepensis based on network pharmacology

Published on Frontiers in Pharmaceutical Sciences 2026,30(1):2-11.
4381 times 1133 times

GUO Changhong YAN Guangjun MIAO Qing LIU Limei XU Jing LIU Chong WANG Yejing XIANG Caiqiong

Rumex chalepensis Network pharmacology Gastric cancer PI3K/Akt signaling pathway Apoptosis Cell cycle arrest Multi-target action Natural anti-tumor drug
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Experimental study on the alleviation of chronic inflammatory pain in mice by schinifoline via the arachidonic acid metabolism pathway

Published on Frontiers in Pharmaceutical Sciences 2026,30(1):52-60.
4666 times 1046 times

ZHANG Xueqin YAN Baofei ZHENG Kang ZHANG Pengpeng

Schinifoline Complete Freund’s adjuvant Chronic inflammatory pain Metabolomics Arachidonic acid Analgesia Metabolic pathway
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The research progress of fibroblast growth factor 21 in retinal neovascularization diseases

Published on New Medicine 2026,36(1):97-102.
9172 times 1266 times

SHI Ruobing ZHU Fangyuan LIU Hang XIAO Xuan YANG Anhuai

Fibroblast growth factor 21 Retinal neovascularization Diabetic retinopathy Retinopathy of prematurity Age-related macular degeneration Retinal vein obstruction
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Network pharmacological exploration of the mechanism of Scutellaria baicalensis antigenic primary biliary cholangitis

Published on Frontiers in Pharmaceutical Sciences 2026,30(2):181-189.
4952 times 1153 times

WANG Chunxia ZHAO Zan GUO Qinghong

Primary biliary cholangitis Scutellaria baicalensis Network pharmacology Molecular docking Molecular dynamics simulation Signaling pathways GO function analysis KEGG pathway enrichment analysis
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Exploring the mechanism of action of Aconitum Heterophyllum in treating gout based on network pharmacology and molecular modeling

Published on Frontiers in Pharmaceutical Sciences 2026,30(2):190-200.
4886 times 1023 times

ZHANG Ruirui CHEN Quansheng ZHANG Bingyin WU Yuwen YAN Caifeng

Aconitum Heterophyllum Gout Network pharmacology Molecular docking Molecular dynamics simulation Active ingredients Signaling pathways Protein-protein interactions
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Research progress on TGF-β pathway inhibitors for treating hepatic fibrosis

Published on Frontiers in Pharmaceutical Sciences 2026,30(2):347-360.
5739 times 1149 times

WU Yalin TIAN Sha

Hepatic fibrosis TGF-β signaling pathway Hepatic stellate cells Inhibitors Therapeutic target Molecular mechanisms Drug delivery systems Traditional Chinese medicine compounds
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The mechanism of Cistanche phenylethanol glycosides in inhibiting tumor growth in nude mice bearing drug-resistant osteosarcoma

Published on Journal of Mathematical Medicine 2026,39(2):92-100.
4365 times 1186 times

DING Juxian XIE Xingwen LI Dingpeng LI Ning XU Wei WANG Kai FANG Yan XU Shihong WANG Xiaoqiang LI Jianguo SU Jiliang

Osteosarcoma Cistanche phenylethanol glycosides MG-63 Tumor cells Apoptosis Mechanism PI3K/AKT/mTOR signaling pathway
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Exploring the mechanism of astragaloside IV in the treatment of ischemic stroke based on integrated pharmacology

Published on Journal of Mathematical Medicine 2026,39(2):101-113.
4914 times 1227 times

LI Bo XU Hao HUANG Xiuxiu HOU Fen ZOU Ziqin LI Qun

Ischemic stroke Astragaloside IV Network pharmacology Molecular docking TNF/NF-κB signaling pathway
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Low-concentration Dexmedetomidine promotes the proliferation and invasion of osteosarcoma cells mediated by TRIO, PKN2 and CKAP5 via ERK1/2-dependent activation

Published on New Medicine 2026,36(2):179-187.
4256 times 1177 times

YANG Hui CHEN Leijie ZHAO Min WANG Zhonghui LIAO Shan CHEN Lianpu GONG Lingli LI Shanshan

Dexmedetomidine Osteosarcoma TRIO PKN2 CKAP5 ERK1/2 pathway
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Mechanism of the medicine pair of Sanhe Decoction in treatment of chronic prostatitis/chronic pelvic pain syndrome and benign prostatic hyperplasia with "homotherapy for heteropathy" based on network pharmacology and molecular docking

Published on Journal of Mathematical Medicine 2026,39(3):179-190.
5133 times 1322 times

LI Shenglong JING Shuaishuai LI Hui ZHANG Qingwei GONG Meisheng LIANG Yonglin ZHOU Jiuyun ZHAO Yongqiang

Chronic prostatitis Chronic pelvic pain syndrome Benign prostatic hy-perplasia Sanhe Decoction Homotherapy for heteropathy Network pharmacology Molecular docking
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Research on the distribution of the syndrome types of early diabetes nephropathy and medication rules of qi-yin deficiency syndrome based on data mining

Published on Journal of Mathematical Medicine 2026,39(3):200-210.
5697 times 1230 times

WANG Zhongjiang DONG Nengfeng LI Bo

Diabetes nephropathy Qi-yin deficiency type Data mining Medication rules Association rules Factor analysis
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The predictive value of AI-based retinal images model for diabetic retinopathy

Published on New Medicine 2026,36(3):282-288.
4956 times 1299 times

LIU Deyou JI Jiangdong LI Bo

Artificial intelligence Diabetic retinopathy Optical coherence tomography angiography Deep learning Predictive model
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Trend analysis and prediction of the disease burden of idiopathic epilepsy in China from 1990 to 2021

Published on New Medicine 2026,36(3):305-312.
4836 times 1332 times

JIA Zhaoxia WU Qian ZHANG Yun

Idiopathic epilepsy Disease burden Disability-adjusted life years Age-standardized rate
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