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Wuhan University
Zhongnan Hospital of Wuhan University
Center for Evidence-Based and Translational Medicine of Wuhan University
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A total of
2260
result was found. Results that relate to
M
SERPINE1 affects the metastasis of colon cancer by regulating MMP-9 and MMP-2
Published on
Journal of Mathematical Medicine
2026,39(4):252-262.
2914 times
717 times
CHEN Dehe
DING Pengpeng
LI Wending
LI Hongtao
Colon cancer
SERPINE1
M
M
P-9
M
M
P-2
M
etastasis
Details
A study on the mechanisms regulation of BIRC5 expression in prostate cancer and its potential targeted therapy
Published on
Journal of Mathematical Medicine
2026,39(4):263-272.
3020 times
775 times
YE Junjie
CHEN Yunyi
HUANG Yingxin
LI Yanliang
WANG Huifeng
Carcino
m
a of prostate
BIRC5 gene
Targeted therapy
M
echanis
m
Details
Efficacy analysis of extended curettage combined with denosumab adjuvant therapy for giant cell tumor of the bone
Published on
Journal of Mathematical Medicine
2026,39(4):273-281.
3548 times
807 times
WEN Riyou
LE Guoping
Giant cell tu
m
or of the bone
Extended curettage
Denosu
m
ab
Relapse rate
Details
Influencing factors of healthcare-seeking delay for pulmonary tuberculosis pa-tients in China from 2014 to 2024: a Meta-analysis
Published on
Journal of Mathematical Medicine
2026,39(4):282-293.
3611 times
752 times
HUANG Chen
AN Xuemei
YANG Tingyu
HONG Zhongxi
LUO Yongyuan
XIONG Xiya
ZHOU Xianyu
Tuberculosis
Healthcare-seeking delay
Influencing factors
M
eta-analysis
Details
Research progress of traditional Chinese medicine on the regulation of Notch signaling pathway in the treatment of rheumatoid arthritis
Published on
Journal of Mathematical Medicine
2026,39(4):294-300.
4064 times
844 times
LI Mingxia
CHEN Junlong
HE Bianqiang
HE Wenkui
GAO Wanpeng
Rheu
m
atoid arthritis
Notch signaling pathway
Traditional Chinese
m
edicine
M
echanis
m
Details
Hemostatic management during the perioperative period in a patient with severe hemophilia A and high-titer FⅧ inhibitors: a case report
Published on
Journal of Mathematical Medicine
2026,39(4):301-306.
3265 times
882 times
WANG Ziqing
ZHANG Xian
He
m
ophilia A
Factor Ⅷ inhibitor
Reco
m
binant activated factor Ⅶ
Os-teofascial Co
m
part
m
ent syndro
m
e
Details
Fertility-sparing treatment for ovarian yolk sac tumor in a woman of childbearing age: a case report
Published on
Journal of Mathematical Medicine
2026,39(4):307-313.
5091 times
858 times
HE Li
CHEN Yuyan
WEI Yi
ZHANG Fan
Ovarian yolk sac tu
m
or
Ovarian
m
alignant ger
m
cell tu
m
or
Childbearing age
Fertility-sparing treat
m
ent
Details
Klinefelter syndrome with diabetes ketoacidosis as the first manifestation: a case report and literature analysis
Published on
Journal of Mathematical Medicine
2026,39(4):314-318.
3460 times
956 times
LIU Xiaoyu
YANG Fan
WU Jing
YIN Wanling
Klinefelter syndro
m
e
Hypogonadis
m
Gyneco
m
astia
Diabetic ketoacidosis
Osteoporosis
Details
Expert consensus for off-label drug use of rare diseases (2026 edition)
Published on
Chinese Journal of Pharmacoepidemiology
2026,35(5):493-507.
3322 times
975 times
DUAN Yuehan
CHEN Chaoyang
ZHANG Yu
CUI Yi-min
WANG Shengfeng
DING Jie
Working Group of the Expert Consensus for Off-Label Drug Use of Rare Diseases
Rare disease
Off-label drug use
Expert consensus
Tho
m
son evidence grading syste
m
Details
Experimental study on the protective effect and safety of different doses of quercetin on the intestinal barrier in sepsis
Published on
Chinese Journal of Pharmacoepidemiology
2026,35(5):517-525.
2153 times
587 times
FENG Mingzhi
SUN Yan
ZHANG Jun
Quercetin
Sepsis
Intestinal epithelial barrier
Anti-infla
m
m
atory
Infection
Details
Cost-effectiveness analysis of sacituzumab tirumotecan versus platinum-based chemotherapy as second-line treatment for progressed EGFR-mutant non-small-cell lung cancer
Published on
Chinese Journal of Pharmacoepidemiology
2026,35(5):553-562.
2857 times
590 times
JIN Lijun
ZHANG Lele
HAN Lu
LYU Zhenye
Sacituzu
m
ab tiru
m
otecan
Non-s
m
all cell lung cancer
EGFR
m
utation
Quality adiusted life year
Incre
m
ental Cost-effectiveness ratio
Cost-effectiveness analysis
Scenaio analysis
Details
Visualization analysis of off-label drug use of Chinese patent medicine based on CiteSpace software
Published on
Chinese Journal of Pharmacoepidemiology
2026,35(5):563-570.
2122 times
599 times
SONG Yifei
WANG Hui
YANG Wenbao
CHEN Xin
JIA Shengwei
ZHANG Huiyue
Chinese patent
m
edicine
Off-label use
Biblio
m
etrics
Visual analysis
Rational drug use
Details
Research progress in pharmacological treatment of mitral regurgitation
Published on
Chinese Journal of Pharmacoepidemiology
2026,35(5):571-578.
2381 times
522 times
LU Qianhong
LYU Junxing
WU Yongjian
XU Haiyan
M
itral regurgitation
Phar
m
acological treat
m
ent
Valvular heart disease
Guideline-directed
m
edical therapy
Prognosis
Details
Environmental chemical exposure and antidepressant efficacy: mechanisms and advances in precision pharmacology prediction models
Published on
Chinese Journal of Pharmacoepidemiology
2026,35(5): 579-588.
2144 times
466 times
WANG Pei
CHEN Wanying
SHANG Nan
ZHANG Ruifen
Antidepressants
Environ
m
ental exposure
Blood-brain barrier
Drug efficacy
Envir-on
m
ental che
m
ical pollutants
Precision phar
m
acology
Details
Research on influencing factors of cognitive function in the middle-aged and elderly people: an empirical analysis based on CHARLS
Published on
Journal of Mathematical Medicine
2026,39(5):319-327.
2954 times
695 times
ZHU Xinya
FENG Jiayun
YE Sha
SHEN Jie
MAI Yiyi
RONG Fen
M
iddle-aged and elderly people
Cognitive function
Influencing factors
Logistic regression
m
odel
Rando
m
forest
m
odel
Details
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